Detailed information NTG0154056

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DE8669_RS00675
• Genome accession: NZ_CP012391
• Coordinates: 126037..127224 (+)
• Length: 395 a.a.
• NCBI ID: WP_002218551.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain DE8669
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 121037..132224

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DE8669_RS00660 (DE8669_0118)	-	121957..122556 (+)	600	WP_002216221.1	DUF4390 domain-containing protein	-
DE8669_RS00665 (DE8669_0119)	-	122556..124676 (+)	2121	WP_002223289.1	sensor histidine kinase	-
DE8669_RS00670 (DE8669_0120)	-	124669..125946 (+)	1278	WP_002218550.1	sigma-54-dependent transcriptional regulator	-
DE8669_RS00675 (DE8669_0121)	dprA	126037..127224 (+)	1188	WP_002218551.1	DNA-processing protein DprA	Machinery gene
DE8669_RS00680 (DE8669_0122)	-	127250..127711 (+)	462	WP_002215351.1	DUF494 domain-containing protein	-
DE8669_RS00685 (DE8669_0123)	topA	127783..130089 (+)	2307	WP_002218552.1	type I DNA topoisomerase	-
DE8669_RS11570	-	130167..130436 (-)	270	WP_206696354.1	YkgJ family cysteine cluster protein	-
DE8669_RS00690 (DE8669_0124)	-	130433..130852 (-)	420	WP_002218553.1	hypothetical protein	-
DE8669_RS00695 (DE8669_0125)	-	130852..131799 (-)	948	WP_002218555.1	hypothetical protein	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 41801.77 Da
• Isoelectric Point: 5.9333

>NTDB_id=154056 DE8669_RS00675 WP_002218551.1 126037..127224(+) (dprA) [Neisseria meningitidis strain DE8669]
MTEDERFAWLQLAFTPYIGAESFLLLLRRFGSASNALSAPAEQVAPAVRHKQAAEAWRNAEKRASARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGKSLGGQNIPVVSGMASGIDT
AAHQGALEAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLVECLDDILNECPGLLQNTGASSYSINKDTPDTGSRAVQT
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=154056 DE8669_RS00675 WP_002218551.1 126037..127224(+) (dprA) [Neisseria meningitidis strain DE8669]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGCTTCCTGCTGCTGCT
GCGCCGTTTCGGCAGCGCGTCAAACGCCCTGTCCGCACCGGCGGAACAGGTCGCCCCGGCGGTGCGGCACAAGCAGGCGG
CCGAGGCTTGGCGCAATGCGGAAAAACGCGCCTCGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGTCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAAGTCGTTGGGCGGGCAAAATATCCCCGTTGTGTCGGGTATGGCTTCCGGTATCGATACT
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGTATAGACCGCATTTACCCGCC
GTCCAATAAAAACCTTGCCTATGAAATCGCCGAAAAAGGATTGATTGTCAGCGAGTTTCCCATCGGTACGCGCCCGTATG
CCGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGCAGGTTACGCTGGTGGTTGAAGCTGCGTTGGAATCC
GGTTCGCTGATTACCGCCGGCTTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGTTCGATAGACAATCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAATTGGTGGAATGCCTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCATCATATTCTATAAATAAGGATACGCCCGACACGGGCAGTCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (341-388)

• DNA recombination-mediator protein A (DNA_processg_A) (79-283)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae MS11	96.203	100	0.962
dprA	Neisseria gonorrhoeae strain FA1090	95.949	100	0.959
dprA	Neisseria meningitidis MC58	90.176	100	0.906
dprA	Neisseria meningitidis strain C311	90.176	100	0.906
dprA	Glaesserella parasuis strain SC1401	40.576	96.709	0.392
dprA	Vibrio cholerae strain A1552	37.531	100	0.377
dprA	Vibrio campbellii strain DS40M4	36.856	98.228	0.362