Detailed information NTG0152676

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: A4265_RS02205
• Genome accession: NZ_CP015238
• Coordinates: 416673..418826 (-)
• Length: 717 a.a.
• NCBI ID: WP_063631789.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NS53
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 411673..423826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A4265_RS02185 (A4265_02035)	comE/blpR	412864..413613 (+)	750	WP_002992578.1	response regulator transcription factor	Regulator
A4265_RS02190 (A4265_02040)	-	413614..414948 (+)	1335	WP_063631787.1	sensor histidine kinase	-
A4265_RS02195 (A4265_08580)	-	415096..415221 (-)	126	WP_011017462.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
A4265_RS02200 (A4265_02045)	-	415298..416662 (-)	1365	WP_063631788.1	bacteriocin secretion accessory protein	-
A4265_RS02205 (A4265_02050)	comA/nlmT	416673..418826 (-)	2154	WP_063631789.1	peptide cleavage/export ABC transporter	Regulator
A4265_RS02215 (A4265_02060)	-	419277..419962 (+)	686	Protein_402	transposase	-
A4265_RS02220 (A4265_02065)	-	420182..420364 (-)	183	WP_002987564.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
A4265_RS02225 (A4265_02070)	-	420379..420624 (-)	246	WP_002994504.1	Blp family class II bacteriocin	-
A4265_RS02230 (A4265_02075)	-	420812..421497 (-)	686	Protein_405	transposase	-
A4265_RS02235 (A4265_02080)	-	421814..422041 (+)	228	WP_021775509.1	Blp family class II bacteriocin	-
A4265_RS02240 (A4265_02085)	-	422054..422254 (+)	201	WP_003060803.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
A4265_RS09275 (A4265_02090)	-	422615..422743 (+)	129	WP_257571835.1	hypothetical protein	-
A4265_RS02260 (A4265_02100)	-	423267..423668 (+)	402	WP_023605036.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80516.43 Da
• Isoelectric Point: 7.0109

>NTDB_id=152676 A4265_RS02205 WP_063631789.1 416673..418826(-) (comA/nlmT) [Streptococcus pyogenes strain NS53]
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHVNKEGKFQHYYVVYQNKKNYLIIGDPDPTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVDYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIETGSHQELMTKQGFYHHLFSG

Nucleotide

• Length: 2154 bp

>NTDB_id=152676 A4265_RS02205 WP_063631789.1 416673..418826(-) (comA/nlmT) [Streptococcus pyogenes strain NS53]
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGCA
TCGTCAAAGCTGCCAAATTAATGGGATTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATGTTAATAAAGAAGGTAAATTCCAACACTACTATGTCGTCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTGACCCGACAGTAAAAGTCACTAAGATGACAAAGGAGCGTTTTACTTCTGAATGGACGGGTG
TCGCTATTTTTCTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGACAAAAAGAACGGTCTAATAAGCTTTTTACCTCTC
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGCATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCGAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAT
GTTATTTTATCCTATATTCGTCATATTTTTGAGCTTCCCATGTCTTTCTTTGCAACACGTCGGACAGGAGAAATCATTTC
ACGGTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCTACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTCCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATATCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGACTATCTGGATAAATCTTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACCAAACTTCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAATTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGGATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGAGGCCAAAAGCAACGAATTGCGCTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAAAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGCA
AAATTATTGAAACAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTGGTTAA

Domains

Predicted by InterProScan.

• ABC transporter transmembrane region (ABC_membrane) (168-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.867	99.721	0.727
comA	Streptococcus mitis NCTC 12261	67.792	99.163	0.672
comA	Streptococcus mitis SK321	67.37	99.163	0.668
comA	Streptococcus pneumoniae Rx1	67.37	99.163	0.668
comA	Streptococcus pneumoniae D39	67.37	99.163	0.668
comA	Streptococcus pneumoniae R6	67.37	99.163	0.668
comA	Streptococcus pneumoniae TIGR4	67.089	99.163	0.665
comA	Streptococcus gordonii str. Challis substr. CH1	66.154	99.721	0.66