Detailed information NTG0145808

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SpyM6D471_RS04670
• Genome accession: NZ_CP011415
• Coordinates: 945957..946793 (-)
• Length: 278 a.a.
• NCBI ID: WP_011184519.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain D471
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 940957..951793

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SpyM6D471_RS04660 (SpyM6D471_04655)	trmFO	942240..943586 (-)	1347	WP_021340038.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
SpyM6D471_RS04665 (SpyM6D471_04660)	topA	943721..945850 (-)	2130	WP_011184520.1	type I DNA topoisomerase	-
SpyM6D471_RS04670 (SpyM6D471_04665)	dprA	945957..946793 (-)	837	WP_011184519.1	DNA-processing protein DprA	Machinery gene
SpyM6D471_RS04675 (SpyM6D471_04670)	-	946858..947649 (-)	792	WP_011184518.1	ribonuclease HII	-
SpyM6D471_RS04680 (SpyM6D471_04675)	ylqF	947639..948487 (-)	849	WP_011184517.1	ribosome biogenesis GTPase YlqF	-
SpyM6D471_RS04685 (SpyM6D471_04680)	-	948706..949146 (+)	441	WP_011017769.1	DUF1836 domain-containing protein	-
SpyM6D471_RS04690 (SpyM6D471_04685)	-	949143..949793 (+)	651	WP_002984629.1	hemolysin III family protein	-
SpyM6D471_RS04695 (SpyM6D471_04690)	-	949910..950821 (+)	912	WP_011184516.1	diacylglycerol kinase family protein	-
SpyM6D471_RS04700 (SpyM6D471_04695)	-	950871..951305 (-)	435	WP_011017767.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31136.17 Da
• Isoelectric Point: 9.2335

>NTDB_id=145808 SpyM6D471_RS04670 WP_011184519.1 945957..946793(-) (dprA) [Streptococcus pyogenes strain D471]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMYILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=145808 SpyM6D471_RS04670 WP_011184519.1 945957..946793(-) (dprA) [Streptococcus pyogenes strain D471]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCTATTGTTGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGTATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363