Detailed information NTG0143227

Bioinformatically predicted

Overview

• Name: comGD
• Type: Machinery gene
• Locus tag: AVT04_RS05770
• Genome accession: NZ_CP013939
• Coordinates: 1069708..1070136 (+)
• Length: 142 a.a.
• NCBI ID: WP_011226626.1
• Uniprot ID: Q5M2G1
• Organism: Streptococcus thermophilus strain S9
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1064708..1075136

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AVT04_RS05750 (AVT04_05750)	-	1067059..1067421 (+)	363	WP_011226630.1	DUF1033 family protein	-
AVT04_RS05755 (AVT04_05755)	comGA/cglA/cilD	1067502..1068443 (+)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
AVT04_RS05760 (AVT04_05760)	comGB	1068325..1069425 (+)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
AVT04_RS05765 (AVT04_05765)	comGC	1069422..1069748 (+)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
AVT04_RS05770 (AVT04_05770)	comGD	1069708..1070136 (+)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
AVT04_RS05775 (AVT04_05775)	comGE	1070108..1070401 (+)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	Machinery gene
AVT04_RS05780 (AVT04_05780)	comGF	1070385..1070822 (+)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
AVT04_RS05785 (AVT04_05785)	comGG	1070800..1071117 (+)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	Machinery gene
AVT04_RS05790 (AVT04_05790)	comGH	1071162..1072118 (+)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
AVT04_RS05795 (AVT04_05795)	-	1072174..1073367 (+)	1194	Protein_1053	acetate kinase	-
AVT04_RS05800 (AVT04_05800)	-	1073616..1073813 (+)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
AVT04_RS11170 (AVT04_05805)	-	1074056..1074481 (+)	426	WP_041827107.1	CPBP family intramembrane glutamic endopeptidase	-
AVT04_RS05810 (AVT04_05810)	-	1074555..1075003 (+)	449	Protein_1056	CAAX protease	-

Sequence

Protein

• Length: 142 a.a.
• Molecular weight: 15859.45 Da
• Isoelectric Point: 10.3330

>NTDB_id=143227 AVT04_RS05770 WP_011226626.1 1069708..1070136(+) (comGD) [Streptococcus thermophilus strain S9]
MRNMVVKAAQWPIRAFTLLESLMTLAVVVFLTLSLSGSVTGIFQQVEINLFYLRFEYLYRDSQRLASAEGSNVELQLTKD
KVSNGRSSLLIPKSIHLDKGQTLVFDAKGGNSSLTKIRFSSDKEVVTYLLNMGSGKYKKTIS

Nucleotide

• Length: 429 bp

>NTDB_id=143227 AVT04_RS05770 WP_011226626.1 1069708..1070136(+) (comGD) [Streptococcus thermophilus strain S9]
ATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGCCAATTAGAGCTTTCACCTTGTTGGAGAGCCTGATGACACTAGCAGT
GGTTGTCTTTCTCACTCTGAGTTTGTCAGGCTCAGTCACAGGTATTTTTCAGCAGGTCGAGATTAATCTTTTTTATCTGC
GTTTTGAGTACCTATATCGAGATAGTCAGCGCTTGGCATCAGCGGAAGGATCTAATGTTGAATTGCAGTTAACTAAGGAT
AAGGTTAGTAATGGAAGGTCTAGTCTGCTTATTCCTAAAAGTATTCATCTGGATAAGGGGCAGACGCTAGTGTTTGATGC
TAAAGGAGGCAACTCTAGCCTCACGAAAATTCGTTTTTCAAGTGATAAGGAGGTGGTGACCTATCTGCTTAACATGGGCA
GTGGTAAATATAAAAAGACGATCTCTTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: Q5M2G1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGD	Streptococcus mutans UA140	52.672	92.254	0.486
comGD	Streptococcus mutans UA159	52.672	92.254	0.486
comGD	Streptococcus gordonii str. Challis substr. CH1	41.429	98.592	0.408
comGD/cglD	Streptococcus pneumoniae Rx1	44.094	89.437	0.394
comGD/cglD	Streptococcus pneumoniae D39	44.094	89.437	0.394
comGD/cglD	Streptococcus pneumoniae R6	44.094	89.437	0.394
comGD/cglD	Streptococcus mitis NCTC 12261	44.094	89.437	0.394
comGD/cglD	Streptococcus pneumoniae TIGR4	44.094	89.437	0.394
comGD/cglD	Streptococcus mitis SK321	43.307	89.437	0.387
comGD	Lactococcus lactis subsp. cremoris KW2	40.909	92.958	0.38