Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   AVT04_RS05775 Genome accession   NZ_CP013939
Coordinates   1070108..1070401 (+) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain S9     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1065108..1075401
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AVT04_RS05750 (AVT04_05750) - 1067059..1067421 (+) 363 WP_011226630.1 DUF1033 family protein -
  AVT04_RS05755 (AVT04_05755) comGA/cglA/cilD 1067502..1068443 (+) 942 WP_011226629.1 competence type IV pilus ATPase ComGA Machinery gene
  AVT04_RS05760 (AVT04_05760) comGB 1068325..1069425 (+) 1101 WP_148148900.1 competence type IV pilus assembly protein ComGB Machinery gene
  AVT04_RS05765 (AVT04_05765) comGC 1069422..1069748 (+) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  AVT04_RS05770 (AVT04_05770) comGD 1069708..1070136 (+) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  AVT04_RS05775 (AVT04_05775) comGE 1070108..1070401 (+) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  AVT04_RS05780 (AVT04_05780) comGF 1070385..1070822 (+) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  AVT04_RS05785 (AVT04_05785) comGG 1070800..1071117 (+) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  AVT04_RS05790 (AVT04_05790) comGH 1071162..1072118 (+) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  AVT04_RS05795 (AVT04_05795) - 1072174..1073367 (+) 1194 Protein_1053 acetate kinase -
  AVT04_RS05800 (AVT04_05800) - 1073616..1073813 (+) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  AVT04_RS11170 (AVT04_05805) - 1074056..1074481 (+) 426 WP_041827107.1 CPBP family intramembrane glutamic endopeptidase -
  AVT04_RS05810 (AVT04_05810) - 1074555..1075003 (+) 449 Protein_1056 CAAX protease -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=143228 AVT04_RS05775 WP_011226625.1 1070108..1070401(+) (comGE) [Streptococcus thermophilus strain S9]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=143228 AVT04_RS05775 WP_011226625.1 1070108..1070401(+) (comGE) [Streptococcus thermophilus strain S9]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361