Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   CUGBS08_RS10525 Genome accession   NZ_CP010874
Coordinates   2065975..2067204 (+) Length   409 a.a.
NCBI ID   WP_000728356.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain CU_GBS_08     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2060975..2072204
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CUGBS08_RS10500 (CUGBS08_02122) - 2062135..2064714 (+) 2580 WP_000154433.1 YfhO family protein -
  CUGBS08_RS10520 (CUGBS08_02126) rlmH 2065295..2065774 (-) 480 WP_000768335.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  CUGBS08_RS10525 (CUGBS08_02127) htrA 2065975..2067204 (+) 1230 WP_000728356.1 S1C family serine protease Regulator
  CUGBS08_RS10530 (CUGBS08_02128) spo0J 2067302..2068075 (+) 774 WP_000456088.1 ParB/RepB/Spo0J family partition protein Regulator
  CUGBS08_RS10535 (CUGBS08_02129) dnaA 2068284..2069645 (+) 1362 WP_000138202.1 chromosomal replication initiator protein DnaA -
  CUGBS08_RS10540 (CUGBS08_02130) dnaN 2069800..2070936 (+) 1137 WP_000581132.1 DNA polymerase III subunit beta -
  CUGBS08_RS10545 (CUGBS08_02131) - 2070994..2071887 (+) 894 WP_000987448.1 diacylglycerol/lipid kinase family protein -
  CUGBS08_RS10550 (CUGBS08_02132) - 2071897..2072094 (+) 198 WP_000285199.1 DUF951 domain-containing protein -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 43104.56 Da        Isoelectric Point: 9.5271

>NTDB_id=140475 CUGBS08_RS10525 WP_000728356.1 2065975..2067204(+) (htrA) [Streptococcus agalactiae strain CU_GBS_08]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVASPSDLQSLLYGHQVGDSITVTFYRGENKQTITIKLTKTSK
DLAKQRANN

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=140475 CUGBS08_RS10525 WP_000728356.1 2065975..2067204(+) (htrA) [Streptococcus agalactiae strain CU_GBS_08]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCTGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAGGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGCATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGAGATTCCATAACAGTAACCTTTTACCGTGGTGAAAATAAACAAACAATCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(106-251)

PDZ domain (PDZ_2)

(300-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

63.104

96.088

0.606
  htrA Streptococcus gordonii str. Challis substr. CH1

57.357

98.044

0.562
  htrA Streptococcus mitis NCTC 12261

56.533

97.311

0.55
  htrA Streptococcus pneumoniae TIGR4

55.037

99.511

0.548
  htrA Streptococcus pneumoniae Rx1

55.037

99.511

0.548
  htrA Streptococcus pneumoniae D39

55.037

99.511

0.548
  htrA Streptococcus pneumoniae R6

55.037

99.511

0.548

Multiple sequence alignment