Detailed information NTG0139504

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: HSISS4_RS06035
• Genome accession: NZ_CP013216
• Coordinates: 1272551..1273462 (+)
• Length: 303 a.a.
• NCBI ID: WP_021143976.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain HSISS4
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 1267551..1278462

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HSISS4_RS06010 (HSISS4_01164)	-	1268071..1268991 (-)	921	WP_021143980.1	multidrug resistance efflux transporter family protein	-
HSISS4_RS06015 (HSISS4_01165)	-	1269116..1269637 (-)	522	WP_235586038.1	RDD family protein	-
HSISS4_RS06020 (HSISS4_01166)	comR	1269854..1270774 (+)	921	WP_021143979.1	helix-turn-helix domain-containing protein	Regulator
HSISS4_RS06025 (HSISS4_01167)	-	1270847..1271683 (+)	837	WP_021143978.1	ABC transporter ATP-binding protein	-
HSISS4_RS06030 (HSISS4_01168)	-	1271676..1272395 (+)	720	WP_059749195.1	ABC transporter permease	-
HSISS4_RS06035 (HSISS4_01169)	comR	1272551..1273462 (+)	912	WP_021143976.1	helix-turn-helix domain-containing protein	Regulator
HSISS4_RS09910	-	1273550..1273648 (-)	99	Protein_1169	XRE family transcriptional regulator	-
HSISS4_RS06040 (HSISS4_01170)	-	1273826..1274338 (-)	513	WP_021143975.1	NAD(P)H-dependent oxidoreductase	-
HSISS4_RS09915 (HSISS4_01171)	-	1274371..1274567 (+)	197	Protein_1171	transposase	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35766.25 Da
• Isoelectric Point: 4.7579

>NTDB_id=139504 HSISS4_RS06035 WP_021143976.1 1272551..1273462(+) (comR) [Streptococcus salivarius strain HSISS4]
MSEDIKIEIGKRIREERERQGLTREHVCDTEEELTVKQLMRIELGRSLPTIVKLQYISDKLGVSLNYLLGETKLDIPEDY
YQAKYKLMKSPVYGDLERIKKKLQDIEEIYEKYIDILPEDELLTIDIIERTLNFISEEKKEDLVEIVFEDYLNQVLKKEE
YTLNDLLLIKYYSVQCQGSSYDKATIEHFRMKLIKQRLQGDELSNVELLGALSAIAGIYVMHHDYKNMKTIVDKMYEVMH
SIMQHSYQPGIAMLEAKYYLFYENNRDKATDLYNKAILLAEAFGDQVFIKNLKIEIEKDLNIE

Nucleotide

• Length: 912 bp

>NTDB_id=139504 HSISS4_RS06035 WP_021143976.1 1272551..1273462(+) (comR) [Streptococcus salivarius strain HSISS4]
ATGTCTGAAGATATTAAAATCGAGATTGGAAAAAGAATTCGTGAAGAACGTGAGCGTCAAGGATTAACACGTGAGCACGT
TTGTGATACCGAAGAAGAATTAACTGTCAAACAGTTGATGAGAATCGAGCTTGGACGTTCTTTACCAACCATTGTCAAAC
TGCAGTATATCAGTGATAAATTGGGAGTTTCCCTCAACTATTTGTTAGGTGAAACAAAACTAGACATTCCTGAAGACTAT
TATCAGGCTAAATATAAACTCATGAAATCTCCTGTCTATGGCGACCTCGAACGTATCAAGAAAAAGCTGCAGGACATTGA
AGAAATTTATGAAAAATATATTGACATTCTACCAGAGGACGAGCTGCTAACCATTGATATCATTGAAAGAACCCTGAATT
TTATATCTGAAGAGAAGAAAGAAGATCTTGTTGAGATTGTATTTGAAGACTATTTGAATCAGGTATTAAAAAAAGAAGAG
TATACCCTGAATGACCTTTTGTTGATAAAATACTACTCTGTACAATGTCAAGGGTCTTCATATGATAAAGCTACAATTGA
GCATTTTCGAATGAAGTTAATAAAACAAAGATTGCAAGGTGATGAATTATCCAATGTGGAACTATTGGGGGCTTTATCAG
CTATAGCTGGGATTTATGTCATGCATCATGACTATAAAAACATGAAAACTATTGTTGATAAAATGTATGAGGTCATGCAT
TCTATTATGCAACATTCCTATCAACCTGGGATAGCAATGCTTGAAGCAAAATATTATCTGTTCTATGAGAACAATAGAGA
TAAAGCAACTGATCTATATAATAAAGCTATCCTACTAGCGGAGGCTTTTGGCGACCAAGTCTTCATCAAAAATCTTAAAA
TAGAAATAGAAAAAGATTTAAATATAGAATAG

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (77-295)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	41.924	96.04	0.403
comR	Streptococcus salivarius strain HSISS4	41.924	96.04	0.403
comR	Streptococcus thermophilus LMD-9	41.581	96.04	0.399
comR	Streptococcus salivarius SK126	41.754	94.059	0.393
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	39.865	97.69	0.389
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	38.356	96.37	0.37