Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   SanJ4211_RS01240 Genome accession   NZ_CP012805
Coordinates   226499..227521 (+) Length   340 a.a.
NCBI ID   WP_041783985.1    Uniprot ID   -
Organism   Streptococcus anginosus strain J4211     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 221499..232521
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4211_RS01215 (SanJ4211_0214) - 222641..223171 (+) 531 WP_003032280.1 FUSC family protein -
  SanJ4211_RS01220 (SanJ4211_0215) - 223248..223607 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  SanJ4211_RS01225 (SanJ4211_0216) glnA 223646..224992 (+) 1347 WP_003027006.1 type I glutamate--ammonia ligase -
  SanJ4211_RS01230 (SanJ4211_0217) - 225181..225546 (+) 366 WP_003027003.1 DUF1033 family protein -
  SanJ4211_RS01235 (SanJ4211_0218) comGA 225616..226557 (+) 942 WP_003027001.1 competence type IV pilus ATPase ComGA Machinery gene
  SanJ4211_RS01240 (SanJ4211_0219) comGB 226499..227521 (+) 1023 WP_041783985.1 competence type IV pilus assembly protein ComGB Machinery gene
  SanJ4211_RS01245 (SanJ4211_0220) comGC 227518..227835 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  SanJ4211_RS01250 (SanJ4211_0221) comGD 227795..228223 (+) 429 WP_021001232.1 competence type IV pilus minor pilin ComGD Machinery gene
  SanJ4211_RS01255 (SanJ4211_0222) comGE/cglE 228195..228488 (+) 294 WP_021001233.1 competence type IV pilus minor pilin ComGE Machinery gene
  SanJ4211_RS01260 (SanJ4211_0223) comGF/cglF 228472..228909 (+) 438 WP_041783987.1 competence type IV pilus minor pilin ComGF Machinery gene
  SanJ4211_RS01265 comGG/cglG 228890..229216 (+) 327 WP_021001234.1 competence type IV pilus minor pilin ComGG Machinery gene
  SanJ4211_RS01270 (SanJ4211_0225) comGH 229288..230241 (+) 954 WP_021001235.1 class I SAM-dependent methyltransferase Machinery gene
  SanJ4211_RS01275 (SanJ4211_0226) - 230288..231487 (+) 1200 WP_057489560.1 acetate kinase -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 39122.46 Da        Isoelectric Point: 9.6306

>NTDB_id=136474 SanJ4211_RS01240 WP_041783985.1 226499..227521(+) (comGB) [Streptococcus anginosus strain J4211]
MQQDMSLLSRQKRKKLSIVRQKKVVELLNNLFSSGFHLAEMIDFLKRSALLEKTYVEKMKEGLATGKPFSEIMASLGFSD
SVVTQLSLAELHGNLSLSLTKIEEYLENVSKVKKKLIEVATYPFILLIFLVFIMLGLRNYLLPQLERQNSATQLISQLPQ
IFLGSLVVVLVLLAIGFYWFRKSSKIVVFSFLARLPFCGTFIQTYLTAYYAREWGNMIGQGLELSQIFQMMQGQRSAMFQ
EIGKDLEIALQNGQEFSQVVKYYPFFKKELGLIIEYGEVKSKLGCELEVYAQKTWETFFKRVHQAMNVIQPLVFVFVALM
IVLLYAAMLLPIYQNMEVQL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=136474 SanJ4211_RS01240 WP_041783985.1 226499..227521(+) (comGB) [Streptococcus anginosus strain J4211]
ATGCAGCAGGACATGTCACTTTTGAGCAGGCAGAAACGGAAAAAATTATCCATAGTTAGGCAGAAAAAAGTCGTAGAGTT
GCTGAATAATCTTTTTTCTAGCGGCTTTCATTTAGCAGAAATGATTGATTTTTTGAAGCGGAGTGCCCTCCTAGAAAAAA
CCTATGTGGAAAAGATGAAAGAGGGTTTAGCAACAGGAAAACCTTTTTCAGAAATTATGGCTAGTTTAGGATTTTCAGAT
AGTGTTGTCACTCAGCTTTCACTGGCAGAGCTACATGGGAATCTCTCACTCAGCCTGACTAAGATTGAGGAATACTTGGA
AAATGTCTCAAAAGTCAAGAAAAAGTTAATTGAGGTAGCCACTTATCCATTCATTTTACTTATTTTTTTAGTATTCATTA
TGTTAGGGCTGCGCAATTATTTACTTCCGCAGTTAGAACGCCAAAATAGTGCAACGCAGCTGATTAGTCAGTTGCCGCAA
ATTTTTCTGGGTTCACTAGTAGTAGTCCTTGTTTTGTTAGCGATAGGTTTTTATTGGTTTAGAAAAAGCTCAAAAATAGT
AGTGTTTAGCTTCTTGGCTCGACTTCCTTTTTGTGGAACTTTTATTCAAACCTATTTGACAGCTTATTATGCGAGAGAAT
GGGGGAATATGATTGGTCAAGGTTTAGAACTTAGTCAGATTTTTCAAATGATGCAAGGGCAACGCTCTGCTATGTTTCAA
GAAATTGGAAAAGATTTAGAAATTGCGTTGCAAAATGGTCAGGAATTTTCACAAGTAGTGAAATATTATCCGTTTTTTAA
AAAGGAATTGGGCTTGATAATTGAATACGGTGAAGTGAAATCCAAATTGGGGTGTGAATTAGAAGTTTATGCCCAAAAAA
CATGGGAGACATTTTTTAAACGTGTTCATCAAGCGATGAATGTCATTCAACCACTAGTGTTTGTCTTTGTGGCTCTAATG
ATTGTATTGTTGTATGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGGTTCAATTATGA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Streptococcus gordonii str. Challis substr. CH1

73.529

100

0.735
  comGB/cglB Streptococcus mitis NCTC 12261

69.527

99.412

0.691
  comGB/cglB Streptococcus mitis SK321

67.857

98.824

0.671
  comGB/cglB Streptococcus pneumoniae TIGR4

67.56

98.824

0.668
  comGB/cglB Streptococcus pneumoniae R6

67.56

98.824

0.668
  comGB/cglB Streptococcus pneumoniae Rx1

67.56

98.824

0.668
  comGB/cglB Streptococcus pneumoniae D39

67.56

98.824

0.668
  comGB Streptococcus mutans UA159

60.882

100

0.609
  comGB Streptococcus mutans UA140

60.588

100

0.606
  comGB Lactococcus lactis subsp. cremoris KW2

52.802

99.706

0.526