Detailed information NTG0136480

Bioinformatically predicted

Overview

• Name: comGH
• Type: Machinery gene
• Locus tag: SanJ4211_RS01270
• Genome accession: NZ_CP012805
• Coordinates: 229288..230241 (+)
• Length: 317 a.a.
• NCBI ID: WP_021001235.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain J4211
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 224288..235241

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SanJ4211_RS01230 (SanJ4211_0217)	-	225181..225546 (+)	366	WP_003027003.1	DUF1033 family protein	-
SanJ4211_RS01235 (SanJ4211_0218)	comGA	225616..226557 (+)	942	WP_003027001.1	competence type IV pilus ATPase ComGA	Machinery gene
SanJ4211_RS01240 (SanJ4211_0219)	comGB	226499..227521 (+)	1023	WP_041783985.1	competence type IV pilus assembly protein ComGB	Machinery gene
SanJ4211_RS01245 (SanJ4211_0220)	comGC	227518..227835 (+)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
SanJ4211_RS01250 (SanJ4211_0221)	comGD	227795..228223 (+)	429	WP_021001232.1	competence type IV pilus minor pilin ComGD	Machinery gene
SanJ4211_RS01255 (SanJ4211_0222)	comGE/cglE	228195..228488 (+)	294	WP_021001233.1	competence type IV pilus minor pilin ComGE	Machinery gene
SanJ4211_RS01260 (SanJ4211_0223)	comGF/cglF	228472..228909 (+)	438	WP_041783987.1	competence type IV pilus minor pilin ComGF	Machinery gene
SanJ4211_RS01265	comGG/cglG	228890..229216 (+)	327	WP_021001234.1	competence type IV pilus minor pilin ComGG	Machinery gene
SanJ4211_RS01270 (SanJ4211_0225)	comGH	229288..230241 (+)	954	WP_021001235.1	class I SAM-dependent methyltransferase	Machinery gene
SanJ4211_RS01275 (SanJ4211_0226)	-	230288..231487 (+)	1200	WP_057489560.1	acetate kinase	-
SanJ4211_RS01280 (SanJ4211_0227)	glmS	231874..233688 (+)	1815	WP_049533317.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 36049.93 Da
• Isoelectric Point: 4.3472

>NTDB_id=136480 SanJ4211_RS01270 WP_021001235.1 229288..230241(+) (comGH) [Streptococcus anginosus strain J4211]
MNFEKIEQAYTLLLENVQEIQNDLLTSFYDALIEQNGSYLDGDIELDSVRQNNEKLKALKLSKEEWRRAYQFLLMKAAQT
EPLQANHQFTPDSIGFILTFLIDQLSKKEHIDILEIGSGMGNLAETILNNTKKNVDYLGLELDDLLIDISASIADVMDAK
VSFVQGDAVRPQVLKESDVIISDLPVGFYPDDNIAMRYEVASRQEHTYAHHLLMEQSLKYLKSDGYAIFLAPNDLLTSSQ
SDLLKKWLQKHAQIVAMIALPESLFGNAAYAKTIFVLKKQDEQAIQPFVYALSDLQNQADLLTFSEKFQNWSQESEI

Nucleotide

• Length: 954 bp

>NTDB_id=136480 SanJ4211_RS01270 WP_021001235.1 229288..230241(+) (comGH) [Streptococcus anginosus strain J4211]
ATGAATTTTGAAAAAATTGAACAGGCTTATACGCTCTTGTTAGAAAATGTCCAAGAAATCCAAAATGATCTTTTAACGAG
CTTTTATGATGCTTTGATAGAGCAAAATGGCAGCTATTTGGACGGGGATATCGAACTAGATAGTGTTCGGCAGAACAATG
AAAAACTGAAAGCGTTGAAATTAAGTAAAGAAGAATGGCGTCGAGCCTACCAATTTTTGCTGATGAAAGCAGCTCAAACA
GAGCCTTTGCAAGCCAATCATCAATTTACTCCAGATTCTATCGGGTTTATCTTAACTTTTCTCATTGACCAATTGAGTAA
AAAAGAACACATTGATATTTTGGAAATTGGTAGCGGAATGGGGAATTTAGCAGAGACCATTCTCAATAATACAAAGAAAA
ATGTGGATTATCTAGGACTGGAATTGGACGATCTGCTAATTGATATATCAGCCAGTATCGCAGATGTGATGGATGCAAAA
GTTAGTTTTGTGCAAGGTGATGCAGTGCGTCCGCAAGTATTGAAAGAAAGCGATGTGATTATCAGTGATTTACCAGTTGG
CTTTTATCCTGATGATAACATTGCGATGCGCTATGAAGTGGCTAGTAGACAGGAGCATACTTATGCTCATCATTTGTTAA
TGGAACAATCGCTCAAGTATCTCAAATCGGATGGTTATGCTATTTTCCTTGCACCGAATGATTTATTGACTAGTTCGCAA
AGTGATTTATTGAAGAAATGGCTACAAAAGCATGCACAAATAGTTGCAATGATTGCGTTACCAGAGTCTCTTTTTGGAAA
TGCAGCATACGCTAAAACAATTTTTGTACTGAAAAAGCAAGATGAACAAGCTATCCAACCATTTGTTTATGCTTTATCTG
ATTTGCAGAATCAAGCGGATTTATTGACATTTAGCGAAAAGTTTCAAAATTGGAGCCAAGAAAGTGAAATTTAA

Domains

Predicted by InterProScan.

• N-6 DNA Methylase (N6_Mtase) (68-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGH	Streptococcus mutans UA140	61.905	99.369	0.615
comGH	Streptococcus mutans UA159	61.587	99.369	0.612