Detailed information NTG0130736

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: HKU360_RS04615
• Genome accession: NZ_CP009612
• Coordinates: 915923..916759 (+)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain HKU360
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 910923..921759

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HKU360_RS04585 (HKU360_00940)	-	911405..911845 (+)	441	WP_024623381.1	hypothetical protein	-
HKU360_RS04590 (HKU360_00941)	-	911895..912806 (-)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
HKU360_RS04595 (HKU360_00942)	trhA	912923..913573 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
HKU360_RS04600 (HKU360_00943)	-	913570..914010 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
HKU360_RS04605 (HKU360_00944)	ylqF	914229..915077 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
HKU360_RS04610 (HKU360_00945)	-	915067..915858 (+)	792	WP_002989771.1	ribonuclease HII	-
HKU360_RS04615 (HKU360_00946)	dprA	915923..916759 (+)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
HKU360_RS04620 (HKU360_00947)	topA	916866..918995 (+)	2130	WP_002989768.1	type I DNA topoisomerase	-
HKU360_RS10305	-	919070..919927 (-)	858	Protein_876	LysR family transcriptional regulator	-
HKU360_RS04630 (HKU360_00949)	-	919967..920533 (+)	567	Protein_877	PTS sugar transporter subunit IIC	-
HKU360_RS04635 (HKU360_00950)	-	920548..921540 (+)	993	WP_002989762.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=130736 HKU360_RS04615 WP_002989770.1 915923..916759(+) (dprA) [Streptococcus pyogenes strain HKU360]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=130736 HKU360_RS04615 WP_002989770.1 915923..916759(+) (dprA) [Streptococcus pyogenes strain HKU360]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367