Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   JT17_RS03540 Genome accession   NZ_CP009237
Coordinates   733218..734480 (-) Length   420 a.a.
NCBI ID   WP_005712502.1    Uniprot ID   -
Organism   Glaesserella parasuis strain KL0318     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 728218..739480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JT17_RS03505 (JT17_03650) - 728231..728650 (+) 420 WP_005714137.1 hotdog fold thioesterase -
  JT17_RS12465 - 729202..729489 (-) 288 WP_016528248.1 hypothetical protein -
  JT17_RS03515 (JT17_03665) trxA 730034..730348 (-) 315 WP_005712493.1 thioredoxin -
  JT17_RS03520 (JT17_03670) - 730645..731274 (-) 630 WP_010785950.1 LysE family transporter -
  JT17_RS03525 (JT17_03675) - 731276..731746 (-) 471 WP_005712497.1 phosphatidylglycerophosphatase A -
  JT17_RS03530 (JT17_03680) thiL 731749..732717 (-) 969 WP_021110497.1 thiamine-phosphate kinase -
  JT17_RS03535 (JT17_03685) nusB 732726..733139 (-) 414 WP_010785952.1 transcription antitermination factor NusB -
  JT17_RS03540 (JT17_03690) comE 733218..734480 (-) 1263 WP_005712502.1 type IV pilus secretin PilQ Machinery gene
  JT17_RS03545 (JT17_03695) comD 734490..734831 (-) 342 WP_232422217.1 hypothetical protein Machinery gene
  JT17_RS03550 (JT17_03700) comC 734876..735406 (-) 531 WP_021119496.1 hypothetical protein Machinery gene
  JT17_RS03555 (JT17_03705) comB 735403..735924 (-) 522 WP_021112068.1 hypothetical protein Machinery gene
  JT17_RS03560 (JT17_03710) comA 735900..736577 (-) 678 WP_021113429.1 hypothetical protein Machinery gene
  JT17_RS03565 (JT17_03715) - 736731..739286 (+) 2556 WP_044009119.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 47051.05 Da        Isoelectric Point: 8.9182

>NTDB_id=127467 JT17_RS03540 WP_005712502.1 733218..734480(-) (comE) [Glaesserella parasuis strain KL0318]
MRYLFLLFFATFPVLANQQISLSIKNAPTAEIIGYLAEETGKNITISDEIKDTKNFRVEKSHFDEILNSLIKTHQLNLKK
ENGIYYIHQAQEHKQHTTAQLVNALPKLITKTIKLHYSKASEVIESLTKGQGNLLSENGYLHFDDRSNSIIVKDSAASVK
NFTQLIETLDKPTEQIAIEARIVTISSEHLQQLGVRWGLFSPNENHYKLAGNLEGNGLTTNNLNVNFPVNPSASVALQIA
AINSRVLHLELTALESENNIEIIASPRLLTTDKKPASIKQGTEIPYAMYSKKKEITDIEFREAVLGLEVTPHISKQNQIL
LDLAISQNSPNNQMNNMMATIDKQEINTQVLAKHGETIVLGGIFQHLIAKGEDKVPLLGSIPVIKRLFSQNRDKISKREL
VIFVTPYIVKSEKMGAEKQK

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=127467 JT17_RS03540 WP_005712502.1 733218..734480(-) (comE) [Glaesserella parasuis strain KL0318]
ATGCGTTATTTATTCCTGCTATTCTTTGCTACTTTTCCTGTATTAGCAAACCAACAAATTTCGCTTTCTATAAAAAATGC
CCCTACGGCAGAAATTATTGGTTATTTAGCTGAAGAAACGGGAAAAAATATTACGATTTCAGATGAAATTAAAGATACAA
AAAATTTCAGAGTAGAAAAAAGCCATTTTGATGAGATATTAAATAGTTTAATCAAAACACATCAATTAAATTTAAAAAAA
GAAAATGGCATTTACTATATTCATCAAGCCCAAGAACATAAACAACATACTACGGCACAATTAGTTAATGCTCTGCCTAA
ATTAATCACCAAAACAATCAAGTTACACTATTCCAAAGCCTCTGAAGTAATAGAGTCTTTGACAAAAGGGCAAGGCAACT
TGCTATCAGAGAATGGTTATCTTCATTTTGATGATCGCAGTAATAGTATTATCGTCAAAGACAGTGCCGCATCGGTTAAA
AACTTTACTCAACTTATTGAAACCCTAGATAAACCAACGGAACAAATTGCAATTGAAGCCCGAATTGTCACGATCAGCAG
TGAACATTTACAACAACTTGGCGTGCGTTGGGGCTTATTTTCCCCTAACGAAAATCACTACAAATTGGCAGGCAATTTAG
AAGGCAACGGATTAACTACCAACAACTTAAACGTAAATTTTCCAGTAAATCCGTCCGCTTCTGTTGCCTTACAAATTGCC
GCTATCAACAGCCGTGTACTTCATTTAGAACTCACCGCATTAGAAAGCGAAAATAACATAGAGATCATTGCAAGCCCTCG
CTTACTCACAACAGATAAAAAACCAGCGAGTATCAAACAAGGTACAGAGATTCCTTATGCAATGTACAGTAAGAAAAAGG
AAATCACCGATATTGAATTTCGTGAAGCGGTTTTGGGGCTAGAAGTCACGCCACATATTTCTAAACAAAATCAGATTTTG
TTAGATCTTGCCATTAGCCAAAATTCGCCAAATAACCAGATGAACAATATGATGGCAACGATTGATAAACAAGAAATTAA
TACACAAGTCCTTGCTAAACACGGCGAAACCATCGTATTAGGCGGTATTTTTCAACATCTGATCGCCAAAGGCGAAGATA
AAGTCCCGCTGTTAGGCAGTATCCCCGTGATTAAACGCTTATTTAGCCAAAACCGAGATAAAATCTCTAAACGAGAATTA
GTGATTTTTGTTACGCCTTATATTGTAAAATCTGAAAAAATGGGAGCGGAAAAGCAGAAATAA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(110-175)

Bacterial type II and III secretion system protein (Secretin)

(253-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

96.667

100

0.967
  comE Haemophilus influenzae Rd KW20

52.706

100

0.533
  comE Haemophilus influenzae 86-028NP

51.765

100

0.524
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

37.44

98.571

0.369
  pilQ Vibrio cholerae strain A1552

37.44

98.571

0.369
  pilQ Vibrio campbellii strain DS40M4

36.019

100

0.362

Multiple sequence alignment