Detailed information NTG0125698

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ID09_RS04920
• Genome accession: NZ_CP008921
• Coordinates: 1008329..1009171 (-)
• Length: 280 a.a.
• NCBI ID: WP_009909860.1
• Uniprot ID: A0A075SDJ3
• Organism: Streptococcus suis 6407
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1003329..1014171

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ID09_RS04900 (ID09_05025)	-	1003774..1004523 (-)	750	WP_024381858.1	HAD family hydrolase	-
ID09_RS04905 (ID09_05030)	rplL	1004648..1005013 (-)	366	WP_002936483.1	50S ribosomal protein L7/L12	-
ID09_RS04910 (ID09_05035)	rplJ	1005079..1005573 (-)	495	WP_002936486.1	50S ribosomal protein L10	-
ID09_RS04915 (ID09_05040)	topA	1006143..1008236 (-)	2094	WP_024381859.1	type I DNA topoisomerase	-
ID09_RS04920 (ID09_05045)	dprA	1008329..1009171 (-)	843	WP_009909860.1	DNA-processing protein DprA	Machinery gene
ID09_RS04925 (ID09_05050)	-	1009230..1009787 (-)	558	WP_009909862.1	sugar O-acetyltransferase	-
ID09_RS04930 (ID09_05055)	-	1009798..1010058 (-)	261	WP_009909865.1	metal-sensitive transcriptional regulator	-
ID09_RS04935 (ID09_05060)	-	1010177..1010500 (+)	324	WP_002936495.1	rhodanese-like domain-containing protein	-
ID09_RS04940 (ID09_05065)	-	1010497..1012149 (+)	1653	WP_002936496.1	FAD-dependent oxidoreductase	-
ID09_RS04945 (ID09_05070)	-	1012257..1012808 (+)	552	WP_024381860.1	DUF1836 domain-containing protein	-
ID09_RS04950 (ID09_05075)	trhA	1012798..1013448 (+)	651	WP_004195686.1	PAQR family membrane homeostasis protein TrhA	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31260.13 Da
• Isoelectric Point: 8.6529

>NTDB_id=125698 ID09_RS04920 WP_009909860.1 1008329..1009171(-) (dprA) [Streptococcus suis 6407]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAVVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGVQSVQKIIKELNNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDKIYPKENRELQTYIGKHHLVLTEYGPGTDPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF

Nucleotide

• Length: 843 bp

>NTDB_id=125698 ID09_RS04920 WP_009909860.1 1008329..1009171(-) (dprA) [Streptococcus suis 6407]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCGGGTTTGACCAATCTTAATGTGAACAAAGTTTTGGCCTATCAAGA
AAAACACGGTAAAAAATTGACCTTGCGAAATGTCGCTGTAGTGTCTGAATGTAAAAATCCAGTTCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCTTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCGCTCAAACAGATTTACAATCCACCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
GGCAGTTGTTGGTACACGAAATGCCAGTAAAAATGGCGTTCAGTCTGTTCAGAAGATTATCAAAGAACTCAACAATCGCT
TTGTCATTGTCAGTGGTTTGGCAAGAGGAATTGATACAGCTGCCCATATTGCTAGCCTGAAAAATGGTGGACAAACCATT
GCCGTTATTGGAACAGGTTTGGATAAGATATATCCCAAAGAAAATAGAGAATTACAGACCTACATCGGAAAACATCATTT
GGTTCTGACTGAATATGGACCAGGTACAGACCCTCTCAAGTACCATTTCCCAGAACGCAATCGCATAATAGCTGGTTTGG
TGGAAGGATTGGTAGTCTGTGAAGCTAAGATGCGGTCTGGTAGCCTCATTACCTGTGAACGTGCCTTGGAAGAAGGAAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGAGCAAAGTG
CGTTACATCCGGCTTGGACATCATTTCAGAGTATCAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

3D structure

• AlphaFold DB: A0A075SDJ3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	69.286	100	0.693
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.571	100	0.636
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.571	100	0.636
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	63.571	100	0.636
dprA/cilB/dalA	Streptococcus mitis SK321	63.571	100	0.636
dprA	Lactococcus lactis subsp. cremoris KW2	60.357	100	0.604
dprA	Bacillus subtilis subsp. subtilis str. 168	51.741	71.786	0.371
dprA	Legionella pneumophila strain ERS1305867	41.7	88.214	0.368