Detailed information NTG0124146

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SP5448_RS04965
• Genome accession: NZ_CP008776
• Coordinates: 963761..964597 (-)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 5448
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 958761..969597

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP5448_RS04945 (SP5448_05155)	-	959003..959995 (-)	993	WP_010922317.1	D-lactate dehydrogenase	-
SP5448_RS04950	-	960010..960555 (-)	546	Protein_942	PTS sugar transporter subunit IIC	-
SP5448_RS09735	-	960568..961450 (+)	883	Protein_943	LysR family transcriptional regulator	-
SP5448_RS04960 (SP5448_05175)	topA	961525..963654 (-)	2130	WP_010922315.1	type I DNA topoisomerase	-
SP5448_RS04965 (SP5448_05180)	dprA	963761..964597 (-)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
SP5448_RS04970 (SP5448_05185)	-	964662..965453 (-)	792	WP_011285534.1	ribonuclease HII	-
SP5448_RS04975 (SP5448_05190)	ylqF	965443..966291 (-)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
SP5448_RS04980 (SP5448_05195)	-	966510..966950 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
SP5448_RS04985 (SP5448_05200)	-	966947..967597 (+)	651	WP_002984629.1	hemolysin III family protein	-
SP5448_RS04990 (SP5448_05205)	-	967714..968625 (+)	912	WP_010922311.1	diacylglycerol kinase family protein	-
SP5448_RS04995 (SP5448_05210)	-	968675..969043 (-)	369	WP_010922310.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=124146 SP5448_RS04965 WP_010922314.1 963761..964597(-) (dprA) [Streptococcus pyogenes strain 5448]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=124146 SP5448_RS04965 WP_010922314.1 963761..964597(-) (dprA) [Streptococcus pyogenes strain 5448]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367