Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   FE90_RS07260 Genome accession   NZ_CP008695
Coordinates   1431941..1432651 (-) Length   236 a.a.
NCBI ID   WP_002985645.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M23ND     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1426941..1437651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FE90_RS07245 (FE90_1455) rnc 1428648..1429340 (-) 693 WP_002985639.1 ribonuclease III -
  FE90_RS07250 (FE90_1456) vicX 1429783..1430592 (-) 810 WP_002985641.1 MBL fold metallo-hydrolase Regulator
  FE90_RS07255 (FE90_1457) vicK 1430596..1431948 (-) 1353 WP_002990673.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FE90_RS07260 (FE90_1458) vicR 1431941..1432651 (-) 711 WP_002985645.1 response regulator YycF Regulator
  FE90_RS07265 (FE90_1459) - 1432813..1433847 (-) 1035 WP_011184290.1 DUF3114 domain-containing protein -
  FE90_RS07270 (FE90_1460) - 1433903..1435150 (-) 1248 WP_038433654.1 AMP-binding protein -
  FE90_RS07275 (FE90_1461) - 1435107..1436255 (-) 1149 WP_002985651.1 acetyl-CoA C-acyltransferase -
  FE90_RS07280 (FE90_1462) - 1436650..1436799 (-) 150 WP_038433655.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27083.99 Da        Isoelectric Point: 4.9038

>NTDB_id=123601 FE90_RS07260 WP_002985645.1 1431941..1432651(-) (vicR) [Streptococcus pyogenes strain M23ND]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=123601 FE90_RS07260 WP_002985645.1 1431941..1432651(-) (vicR) [Streptococcus pyogenes strain M23ND]
ATGAAAAAAATACTTATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGTTGTCGGCT
AAAGATAGTGAGTTTGACAAGGTTATTGGACTTGAAATTGGGGCTGATGATTACGTGACCAAGCCCTTTTCTAATCGGGA
ATTGCTGGCGCGTGTCAAGGCTCATCTGCGTCGTACCGAAACTATTGAGACGGCTGTTGCAGAAGAAAATGCTTCTTCAG
GTACACAGGAACTAACCATTGGTAATTTACAGATTTTACCAGATGCGTTTGTTGCTAAAAAACATGGTCAAGAGGTAGAG
TTGACCCATCGTGAATTTGAACTATTGCATCATCTAGCTAACCATATGGGTCAGGTGATGACACGAGAACACTTATTGGA
AATTGTTTGGGGATATGATTATTTTGGCGATGTGCGCACGGTTGATGTGACTGTTCGTCGTCTCCGTGAAAAAATTGAAG
ATACACCAAGTCGTCCTGAGTATATTTTAACAAGACGTGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

36.91

98.729

0.364

Multiple sequence alignment