Detailed information NTG0123580

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: FE90_RS03805
• Genome accession: NZ_CP008695
• Coordinates: 722107..722943 (-)
• Length: 278 a.a.
• NCBI ID: WP_030127252.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain M23ND
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 717107..727943

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FE90_RS03795 (FE90_0754)	trmFO	718390..719736 (-)	1347	WP_021340038.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
FE90_RS03800 (FE90_0755)	topA	719871..722000 (-)	2130	WP_038433403.1	type I DNA topoisomerase	-
FE90_RS03805 (FE90_0756)	dprA	722107..722943 (-)	837	WP_030127252.1	DNA-processing protein DprA	Machinery gene
FE90_RS03810 (FE90_0757)	-	723008..723799 (-)	792	WP_038433404.1	ribonuclease HII	-
FE90_RS03815 (FE90_0758)	ylqF	723789..724637 (-)	849	WP_038433405.1	ribosome biogenesis GTPase YlqF	-
FE90_RS03820 (FE90_0759)	-	724856..725296 (+)	441	WP_011017769.1	DUF1836 domain-containing protein	-
FE90_RS03825 (FE90_0760)	trhA	725293..725943 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
FE90_RS03830 (FE90_0761)	-	726060..726971 (+)	912	WP_038433406.1	diacylglycerol/lipid kinase family protein	-
FE90_RS03835 (FE90_0762)	-	727021..727455 (-)	435	WP_038433407.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31087.09 Da
• Isoelectric Point: 9.2565

>NTDB_id=123580 FE90_RS03805 WP_030127252.1 722107..722943(-) (dprA) [Streptococcus pyogenes strain M23ND]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSNTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=123580 FE90_RS03805 WP_030127252.1 722107..722943(-) (dprA) [Streptococcus pyogenes strain M23ND]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTTGGCTCCAGACGCTCAAGCAATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367