Detailed information NTG0120844

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DI45_RS04535
• Genome accession: NZ_CP007560
• Coordinates: 865228..866064 (-)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NGAS743
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 860228..871064

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DI45_RS04515 (DI45_04705)	-	860462..861454 (-)	993	WP_047235282.1	D-lactate dehydrogenase	-
DI45_RS04520	-	861469..862034 (-)	566	Protein_856	PTS sugar transporter subunit IIC	-
DI45_RS10315	-	862074..862916 (+)	843	Protein_857	LysR family transcriptional regulator	-
DI45_RS04530 (DI45_04725)	topA	862992..865121 (-)	2130	WP_047235284.1	type I DNA topoisomerase	-
DI45_RS04535 (DI45_04730)	dprA	865228..866064 (-)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
DI45_RS04540 (DI45_04735)	-	866129..866920 (-)	792	WP_047235285.1	ribonuclease HII	-
DI45_RS04545 (DI45_04740)	ylqF	866910..867758 (-)	849	WP_047235286.1	ribosome biogenesis GTPase YlqF	-
DI45_RS04550 (DI45_04745)	-	867977..868417 (+)	441	WP_011017769.1	DUF1836 domain-containing protein	-
DI45_RS04555 (DI45_04750)	trhA	868414..869064 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
DI45_RS04560 (DI45_04755)	-	869181..870092 (+)	912	WP_047235287.1	diacylglycerol/lipid kinase family protein	-
DI45_RS04565 (DI45_04760)	-	870142..870516 (-)	375	WP_023611058.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=120844 DI45_RS04535 WP_002995009.1 865228..866064(-) (dprA) [Streptococcus pyogenes strain NGAS743]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=120844 DI45_RS04535 WP_002995009.1 865228..866064(-) (dprA) [Streptococcus pyogenes strain NGAS743]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367