Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   SPAP1_RS04465 Genome accession   NZ_CP007537
Coordinates   854685..854873 (+) Length   62 a.a.
NCBI ID   WP_011285559.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain AP1     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context


Location: 849685..859873
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPAP1_RS10590 (SPAP1_04405) - 849742..849864 (+) 123 WP_015055953.1 hypothetical protein -
  SPAP1_RS04425 (SPAP1_04410) - 849878..850201 (+) 324 WP_015055952.1 hypothetical protein -
  SPAP1_RS04430 (SPAP1_04415) - 850201..850533 (+) 333 WP_011285562.1 phage holin -
  SPAP1_RS04435 (SPAP1_04420) - 850535..851299 (+) 765 WP_011285561.1 CHAP domain-containing protein -
  SPAP1_RS04440 (SPAP1_04425) - 851311..851913 (+) 603 WP_011054796.1 hypothetical protein -
  SPAP1_RS04445 (SPAP1_04430) - 851924..852697 (+) 774 WP_011054795.1 hypothetical protein -
  SPAP1_RS04450 (SPAP1_04435) - 852707..852928 (+) 222 WP_009880241.1 hypothetical protein -
  SPAP1_RS04455 (SPAP1_04440) - 852928..853587 (+) 660 WP_009880240.1 hypothetical protein -
  SPAP1_RS04460 (SPAP1_04445) speA 853709..854464 (-) 756 WP_009880239.1 streptococcal pyrogenic exotoxin SpeA -
  SPAP1_RS04465 (SPAP1_04450) prx 854685..854873 (+) 189 WP_011285559.1 hypothetical protein Regulator
  SPAP1_RS04470 (SPAP1_04455) - 855464..856078 (+) 615 WP_011285558.1 TVP38/TMEM64 family protein -
  SPAP1_RS04475 (SPAP1_04460) - 856205..856990 (-) 786 WP_010922378.1 hypothetical protein -
  SPAP1_RS04480 (SPAP1_04465) - 857000..857698 (-) 699 WP_002984437.1 ABC transporter ATP-binding protein -
  SPAP1_RS04485 (SPAP1_04470) - 857698..858069 (-) 372 WP_010922377.1 GntR family transcriptional regulator -

Sequence


Protein


Download         Length: 62 a.a.        Molecular weight: 7290.41 Da        Isoelectric Point: 4.3313

>NTDB_id=120629 SPAP1_RS04465 WP_011285559.1 854685..854873(+) (prx) [Streptococcus pyogenes strain AP1]
MLYIDEFKEAIDKGYILGDTVAIVRKNGKIFDYVLPHEKVRDDEVVTVERVEEVMVELDYIK

Nucleotide


Download         Length: 189 bp        

>NTDB_id=120629 SPAP1_RS04465 WP_011285559.1 854685..854873(+) (prx) [Streptococcus pyogenes strain AP1]
ATGTTATATATAGATGAGTTTAAAGAAGCGATTGATAAGGGGTATATTTTAGGTGACACAGTAGCGATAGTGCGTAAAAA
CGGAAAGATATTTGATTATGTGTTACCACACGAAAAAGTGAGAGATGATGAAGTTGTGACGGTAGAGAGAGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

95.161

0.952

  prx Streptococcus pyogenes MGAS315

79.032

100

0.79

  prx Streptococcus pyogenes MGAS8232

76.271

95.161

0.726

  prx Streptococcus pyogenes MGAS315

76.271

95.161

0.726

  prx Streptococcus pyogenes MGAS315

74.576

95.161

0.71

  prx Streptococcus pyogenes MGAS315

69.492

95.161

0.661

  prx Streptococcus pyogenes MGAS315

82.927

66.129

0.548


Multiple sequence alignment