Detailed information NTG0118034

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: STAB1101_RS04160
• Genome accession: NZ_CP007240
• Coordinates: 834125..834961 (+)
• Length: 278 a.a.
• NCBI ID: WP_038431356.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 7F7
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 829125..839961

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STAB1101_RS04130 (STAB1101_04130)	-	829607..830047 (+)	441	WP_009880949.1	hypothetical protein	-
STAB1101_RS04135 (STAB1101_04135)	-	830097..831008 (-)	912	WP_038431354.1	diacylglycerol/lipid kinase family protein	-
STAB1101_RS04140 (STAB1101_04140)	trhA	831125..831775 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
STAB1101_RS04145 (STAB1101_04145)	-	831772..832212 (-)	441	WP_002984627.1	DUF1836 domain-containing protein	-
STAB1101_RS04150 (STAB1101_04150)	ylqF	832431..833279 (+)	849	WP_038431355.1	ribosome biogenesis GTPase YlqF	-
STAB1101_RS04155 (STAB1101_04155)	-	833269..834060 (+)	792	WP_002995007.1	ribonuclease HII	-
STAB1101_RS04160 (STAB1101_04160)	dprA	834125..834961 (+)	837	WP_038431356.1	DNA-processing protein DprA	Machinery gene
STAB1101_RS04165 (STAB1101_04165)	topA	835068..837197 (+)	2130	WP_002984618.1	type I DNA topoisomerase	-
STAB1101_RS04170 (STAB1101_04170)	trmFO	837332..838678 (+)	1347	WP_021733693.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30982.96 Da
• Isoelectric Point: 8.8230

>NTDB_id=118034 STAB1101_RS04160 WP_038431356.1 834125..834961(+) (dprA) [Streptococcus pyogenes strain 7F7]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDIGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=118034 STAB1101_RS04160 WP_038431356.1 834125..834961(+) (dprA) [Streptococcus pyogenes strain 7F7]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATATCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363