Detailed information NTG1171344

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: DYB47_RS09540
• Genome accession: NZ_UHFV01000002
• Coordinates: 1915607..1916812 (+)
• Length: 401 a.a.
• NCBI ID: WP_003081517.1
• Uniprot ID: G5JXJ8
• Organism: Streptococcus macacae NCTC 11558
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1910607..1921812

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DYB47_RS09505 (NCTC11558_01928)	-	1911355..1912980 (+)	1626	WP_003081086.1	ABC-F family ATP-binding cassette domain-containing protein	-
DYB47_RS09510 (NCTC11558_01929)	tnpA	1913222..1913617 (-)	396	WP_003080128.1	IS200/IS605 family transposase	-
DYB47_RS09530 (NCTC11558_01933)	-	1914223..1914894 (-)	672	WP_003082423.1	YoaK family protein	-
DYB47_RS09535 (NCTC11558_01934)	rlmH	1914959..1915438 (-)	480	WP_003079652.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
DYB47_RS09540 (NCTC11558_01935)	htrA	1915607..1916812 (+)	1206	WP_003081517.1	S1C family serine protease	Regulator
DYB47_RS09545 (NCTC11558_01936)	spo0J	1917026..1917793 (+)	768	WP_003078711.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 401 a.a.
• Molecular weight: 42908.51 Da
• Isoelectric Point: 9.1194

>NTDB_id=1171344 DYB47_RS09540 WP_003081517.1 1915607..1916812(+) (htrA) [Streptococcus macacae NCTC 11558]
MNNMKSNPFLKWFLPFLAVFLSFILGISAILIFNWVSGNGGKTNQKTTVSSVVYDINTETTKAVKNVKNSVVSVINYQKI
DNRYYNYDNASEGKNKSEDGLGVYGEGSGVIYRKSGNDAYVVTNNHVIKDAKKLEIMLANGKKVVGKLVGSDTYSDLAVI
KISSKQVTTVAEFADSDKLKVGEPAIAIGSPLGSDYANSVTEGIVSSLSRTVTSQNEEGETISTNAIQTDAAINPGNSGG
ALVNIKGQVIGINSSKIASSTGSKNGVAVEGMGFAIPANDVRSIINQLEENGEVIRPALGISMANLSEASTSDRDTLKIP
ENVTSGIVVLSTESGMPADNKLKKYDVITEIDGKKVASISDLQSALYKHKKGDKVKITFYRGNDKKNIEIELTKTSKDLN
H

Nucleotide

• Length: 1206 bp

>NTDB_id=1171344 DYB47_RS09540 WP_003081517.1 1915607..1916812(+) (htrA) [Streptococcus macacae NCTC 11558]
GTGAATAATATGAAATCAAATCCTTTTTTAAAATGGTTTTTGCCATTTTTAGCAGTATTCCTTAGTTTTATACTCGGAAT
TTCTGCAATACTTATTTTTAACTGGGTATCCGGTAATGGTGGAAAAACAAACCAAAAAACAACTGTCAGCAGTGTCGTTT
ATGATATTAATACTGAAACAACTAAAGCTGTCAAAAATGTTAAAAATTCTGTAGTCTCAGTTATTAATTATCAAAAAATA
GATAATCGCTACTATAATTACGATAATGCTTCTGAAGGAAAAAATAAATCAGAAGATGGGTTAGGTGTATACGGCGAAGG
GTCTGGCGTTATTTATAGAAAAAGTGGAAATGATGCTTACGTAGTCACCAATAATCATGTTATTAAAGATGCCAAAAAAT
TAGAAATTATGTTGGCTAATGGAAAAAAAGTTGTTGGTAAACTTGTGGGTTCAGATACATACTCAGATTTAGCTGTTATT
AAAATTTCTTCAAAACAAGTTACTACAGTAGCAGAATTTGCTGATTCTGATAAACTAAAAGTAGGAGAACCAGCCATTGC
AATTGGTAGTCCATTGGGTAGTGATTATGCTAATTCTGTTACAGAAGGTATTGTGTCCAGCCTCAGCCGTACCGTAACCT
CGCAAAATGAAGAAGGCGAAACTATTTCAACCAATGCTATCCAAACAGATGCTGCAATCAATCCTGGTAACTCAGGAGGT
GCTTTAGTCAATATCAAAGGACAAGTCATTGGAATTAATTCAAGTAAAATTGCATCAAGTACTGGCTCTAAAAATGGCGT
TGCTGTGGAAGGAATGGGATTTGCCATTCCCGCTAATGACGTTCGTTCCATTATCAATCAATTAGAAGAAAATGGTGAAG
TAATTCGCCCTGCCCTCGGTATTTCAATGGCTAATTTAAGTGAAGCTTCAACAAGTGATAGAGATACACTTAAAATCCCA
GAAAACGTTACAAGCGGTATTGTCGTTCTTTCGACAGAATCTGGCATGCCAGCCGATAACAAACTGAAGAAATATGATGT
CATTACGGAAATTGATGGTAAAAAAGTGGCTTCTATTAGTGACTTACAAAGTGCCCTTTACAAACATAAAAAAGGTGATA
AAGTGAAAATTACTTTCTATCGCGGTAATGATAAGAAAAACATTGAAATCGAGTTAACAAAAACAAGTAAAGATCTCAAT
CATTGA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (48-397)

• PDZ domain (PDZ_2) (297-392)

• Trypsin-like peptidase domain (Trypsin_2) (107-252)

3D structure

• AlphaFold DB: G5JXJ8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	83.333	100	0.835
htrA	Streptococcus gordonii str. Challis substr. CH1	56.281	99.252	0.559
htrA	Streptococcus pneumoniae Rx1	53.234	100	0.534
htrA	Streptococcus pneumoniae TIGR4	53.234	100	0.534
htrA	Streptococcus pneumoniae D39	53.234	100	0.534
htrA	Streptococcus pneumoniae R6	53.234	100	0.534
htrA	Streptococcus mitis NCTC 12261	53.807	98.254	0.529