Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   DYB47_RS08355 Genome accession   NZ_UHFV01000002
Coordinates   1662408..1664639 (+) Length   743 a.a.
NCBI ID   WP_115277017.1    Uniprot ID   -
Organism   Streptococcus macacae NCTC 11558     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1657408..1669639
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DYB47_RS08305 (NCTC11558_01686) - 1657870..1658145 (-) 276 WP_003078485.1 Blp family class II bacteriocin -
  DYB47_RS08310 (NCTC11558_01687) - 1658600..1658764 (-) 165 WP_003080849.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  DYB47_RS08315 (NCTC11558_01688) - 1658800..1658979 (-) 180 WP_003078582.1 Blp family class II bacteriocin -
  DYB47_RS08320 (NCTC11558_01689) - 1659431..1659595 (-) 165 WP_003080849.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  DYB47_RS08325 (NCTC11558_01690) - 1659635..1659826 (-) 192 WP_115277053.1 Blp family class II bacteriocin -
  DYB47_RS08335 (NCTC11558_01691) - 1660178..1660363 (-) 186 WP_002276162.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  DYB47_RS08340 (NCTC11558_01692) - 1660501..1660662 (-) 162 WP_003078564.1 Blp family class II bacteriocin -
  DYB47_RS08345 (NCTC11558_01693) - 1660704..1660958 (-) 255 WP_050584916.1 Blp family class II bacteriocin -
  DYB47_RS08350 (NCTC11558_01694) - 1661382..1661663 (+) 282 WP_003078881.1 hypothetical protein -
  DYB47_RS08355 (NCTC11558_01695) comA/nlmT 1662408..1664639 (+) 2232 WP_115277017.1 peptide cleavage/export ABC transporter Regulator
  DYB47_RS08360 (NCTC11558_01696) comB 1664652..1665659 (+) 1008 WP_003080055.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  DYB47_RS08365 (NCTC11558_01697) - 1665918..1666061 (-) 144 WP_003078833.1 bacteriocin -
  DYB47_RS08375 (NCTC11558_01698) - 1666353..1667399 (-) 1047 WP_003080585.1 thiol reductase thioredoxin -
  DYB47_RS08385 (NCTC11558_01699) - 1668218..1668514 (-) 297 WP_003080053.1 bacteriocin immunity protein -
  DYB47_RS08390 (NCTC11558_01700) - 1668514..1668726 (-) 213 WP_003079955.1 leucocin A/sakacin P family class II bacteriocin -
  DYB47_RS08395 (NCTC11558_01701) - 1669296..1669484 (-) 189 WP_003079001.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 743 a.a.        Molecular weight: 83429.80 Da        Isoelectric Point: 6.7843

>NTDB_id=1171336 DYB47_RS08355 WP_115277017.1 1662408..1664639(+) (comA/nlmT) [Streptococcus macacae NCTC 11558]
MRKVEVMLDSFKSALQQFAASIRFKFKSLRSYKYVPQIDSRDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGI
VEAAKKMKFETRAIKADMSLFDVEDIPYPFIVHIVKDGKLQHYYVVYGQEKEKVIIGDPDPTVKITKMSKSQFAEEWTGV
AIFLAPEPSYEPHKDEKNGLSSFFPLILKQKALLSYIIMASLMVTLIDIAGSYYLQGILDEYIPNQLISTLGIISIGLII
TYIIQQMMEFAKGYLLVVLSQRLVIDVILSYIRHIFTLPMSFFATRRTGEITSRFSDANSIIDAVASTIFSIFLDLTMLI
LVGSVLLIQNGNLFLLTLISIPIYTVIIFVFMKPFEKMNQEVMQSNSMVSSAIIEDINGIETIKSLTSETARYQNIDSEF
VDYLDKSFKLHKYETLQTSLKKGAQLILNVVILWCGAQLVMDDKISVGQLITYNSLLTYFSNPIENIINLQTKLQSARVA
NNRLNEVYLVESEFNDTGTLSDSDFLAGDITFEDLSYKYGFGRDTLSDINLRIKKNDKVSIVGVSGSGKTTLAKMIVHFY
DPYKGHIRINGNDLKTIDKTTLRQYINYLPQQAYIFSGTIFENLTLGAKEGISQADVLKACEIAEIRSDIEQMPMGYQTE
LSDGAGLSGGQKQRVALARALLTKSPVLILDEATSSLDVLTEKKIMDNLLQMADKTVIFVAHRLSISQRTNRVIVMDKGK
IIEEGTHSELIAANGFYHHLFNK

Nucleotide


Download         Length: 2232 bp        

>NTDB_id=1171336 DYB47_RS08355 WP_115277017.1 1662408..1664639(+) (comA/nlmT) [Streptococcus macacae NCTC 11558]
ATGAGAAAGGTAGAGGTTATGTTAGATTCCTTCAAATCTGCTTTACAGCAGTTCGCCGCCAGCATACGCTTTAAGTTCAA
ATCATTACGATCTTATAAATATGTTCCGCAGATAGACTCCAGGGATTGTGGGGTCGCTGCCTTGGCTTCCATCGCCAAAT
ATTATGGCTCGGATTATTCATTAGCTCACTTGCGAGAACTGGCTAAAACCAACAAGGAAGGTACAACTGCACTGGGTATT
GTGGAAGCGGCCAAAAAGATGAAATTTGAAACACGCGCTATTAAAGCCGATATGTCTCTCTTTGATGTAGAGGATATTCC
TTATCCTTTTATCGTCCATATCGTCAAAGATGGCAAGTTGCAGCACTACTACGTTGTCTACGGTCAGGAAAAAGAAAAAG
TAATCATTGGCGACCCTGATCCTACTGTTAAAATAACAAAAATGTCCAAATCGCAATTTGCAGAAGAATGGACAGGTGTT
GCTATTTTTCTGGCACCTGAACCTAGTTATGAACCGCATAAAGACGAAAAGAATGGCTTATCTAGTTTTTTCCCTCTCAT
ATTAAAGCAAAAAGCACTTCTTAGTTACATTATCATGGCCAGTTTAATGGTGACACTGATTGATATCGCAGGTTCCTATT
ATCTACAAGGTATTCTGGATGAATATATCCCTAATCAGCTCATTTCAACACTGGGTATTATCTCTATTGGCTTAATTATC
ACCTATATCATCCAACAGATGATGGAGTTTGCCAAAGGTTACTTACTGGTGGTCCTAAGTCAGCGTCTTGTTATTGATGT
TATCCTTTCTTATATTAGACACATCTTTACCCTGCCGATGTCTTTTTTTGCTACAAGAAGAACAGGGGAAATTACCTCAC
GTTTCTCTGATGCTAATTCCATTATTGATGCCGTGGCTTCAACCATTTTTTCTATCTTTTTGGACCTTACCATGCTTATT
TTAGTCGGCAGTGTCCTATTGATACAAAATGGCAACCTTTTCCTGCTTACACTCATTTCAATTCCTATCTATACAGTGAT
TATCTTTGTTTTCATGAAACCTTTTGAAAAAATGAATCAGGAAGTCATGCAGAGCAATTCGATGGTTTCTTCTGCCATCA
TTGAAGATATCAATGGTATTGAAACCATTAAATCTTTAACCAGTGAAACTGCCCGTTATCAAAATATTGACAGTGAATTT
GTGGATTATTTGGACAAATCTTTCAAACTCCATAAATATGAAACGCTGCAAACATCACTTAAAAAAGGGGCTCAATTGAT
TCTCAACGTTGTCATTTTGTGGTGCGGTGCTCAATTGGTTATGGATGATAAAATATCGGTCGGCCAGCTCATTACTTATA
ATTCTTTATTAACCTACTTTTCTAATCCTATTGAAAATATTATCAACCTGCAAACCAAACTGCAGTCTGCCAGAGTGGCT
AATAATCGTTTAAATGAAGTTTATCTTGTCGAATCAGAATTTAACGATACTGGAACTTTATCAGACAGTGACTTCCTTGC
TGGAGATATTACTTTTGAAGACTTATCTTATAAGTATGGTTTTGGAAGAGACACTTTATCAGATATTAATTTAAGGATCA
AAAAAAATGATAAAGTCAGTATCGTTGGTGTCAGCGGATCTGGAAAGACCACTCTAGCGAAAATGATTGTTCATTTTTAT
GACCCTTATAAGGGACATATTCGAATTAATGGCAATGACTTAAAAACAATTGACAAAACCACTTTGCGGCAATATATCAA
TTATCTGCCGCAGCAGGCTTATATCTTTAGTGGAACTATCTTTGAAAACCTAACATTAGGAGCTAAAGAAGGCATTAGTC
AGGCAGATGTTCTAAAGGCTTGTGAAATTGCTGAAATTCGCTCAGATATTGAACAAATGCCTATGGGCTATCAAACAGAA
CTCTCTGACGGAGCCGGTCTATCAGGCGGACAAAAACAGCGGGTTGCTTTAGCACGTGCACTTTTAACAAAGTCTCCTGT
TTTAATTCTTGATGAAGCTACCAGCAGTCTTGATGTCCTTACTGAGAAAAAAATTATGGATAACCTGCTGCAGATGGCAG
ACAAGACTGTTATCTTTGTTGCTCATAGACTCAGTATCTCTCAGCGGACCAATAGAGTTATTGTTATGGATAAAGGAAAA
ATTATTGAAGAAGGTACACATAGTGAACTTATTGCAGCAAATGGTTTTTATCATCACTTATTTAACAAATAG

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(32-168)

ABC transporter transmembrane region (ABC_membrane)

(196-463)

ABC transporter (ABC_tran)

(526-675)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

78.401

95.962

0.752
  comA Streptococcus mitis NCTC 12261

66.056

95.559

0.631
  comA Streptococcus mitis SK321

65.634

95.559

0.627
  comA Streptococcus pneumoniae D39

65.493

95.559

0.626
  comA Streptococcus pneumoniae Rx1

65.493

95.559

0.626
  comA Streptococcus pneumoniae R6

65.493

95.559

0.626
  comA Streptococcus gordonii str. Challis substr. CH1

65.035

96.231

0.626
  comA Streptococcus pneumoniae TIGR4

65.211

95.559

0.623

Multiple sequence alignment