Detailed information NTG1171337

Bioinformatically predicted

Overview

• Name: comB
• Type: Regulator
• Locus tag: DYB47_RS08360
• Genome accession: NZ_UHFV01000002
• Coordinates: 1664652..1665659 (+)
• Length: 335 a.a.
• NCBI ID: WP_003080055.1
• Uniprot ID: G5JUW9
• Organism: Streptococcus macacae NCTC 11558
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1659652..1670659

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DYB47_RS08335 (NCTC11558_01691)	-	1660178..1660363 (-)	186	WP_002276162.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
DYB47_RS08340 (NCTC11558_01692)	-	1660501..1660662 (-)	162	WP_003078564.1	Blp family class II bacteriocin	-
DYB47_RS08345 (NCTC11558_01693)	-	1660704..1660958 (-)	255	WP_050584916.1	Blp family class II bacteriocin	-
DYB47_RS08350 (NCTC11558_01694)	-	1661382..1661663 (+)	282	WP_003078881.1	hypothetical protein	-
DYB47_RS08355 (NCTC11558_01695)	comA/nlmT	1662408..1664639 (+)	2232	WP_115277017.1	peptide cleavage/export ABC transporter	Regulator
DYB47_RS08360 (NCTC11558_01696)	comB	1664652..1665659 (+)	1008	WP_003080055.1	HlyD family efflux transporter periplasmic adaptor subunit	Regulator
DYB47_RS08365 (NCTC11558_01697)	-	1665918..1666061 (-)	144	WP_003078833.1	bacteriocin	-
DYB47_RS08375 (NCTC11558_01698)	-	1666353..1667399 (-)	1047	WP_003080585.1	thiol reductase thioredoxin	-
DYB47_RS08385 (NCTC11558_01699)	-	1668218..1668514 (-)	297	WP_003080053.1	bacteriocin immunity protein	-
DYB47_RS08390 (NCTC11558_01700)	-	1668514..1668726 (-)	213	WP_003079955.1	leucocin A/sakacin P family class II bacteriocin	-
DYB47_RS08395 (NCTC11558_01701)	-	1669296..1669484 (-)	189	WP_003079001.1	Blp family class II bacteriocin	-
DYB47_RS08400 (NCTC11558_01702)	-	1669495..1669722 (-)	228	WP_003081384.1	Blp family class II bacteriocin	-
DYB47_RS08405 (NCTC11558_01703)	-	1670164..1670592 (-)	429	WP_003078653.1	hypothetical protein	-

Sequence

Protein

• Length: 335 a.a.
• Molecular weight: 38193.87 Da
• Isoelectric Point: 10.7877

>NTDB_id=1171337 DYB47_RS08360 WP_003080055.1 1664652..1665659(+) (comB) [Streptococcus macacae NCTC 11558]
MNPNLFKSAEFYRRRYHNFATVLIIPLVCLLVFLFIFLLFAKKEVTVLSNGEISPLKVIDVIQSKSDYPISENNLTDNRA
VKKGDVLIQYVNPAANTRQGGNNQNQSQNKQNKNQQQNNKNQKNGNQGQKNQNQNQNKKDQKNNNQSQQNKQGQKKTNQS
QNQQNKNQNKNQSQNKQNGNQNQNNWNQNNQNDKVTASQDGVIHTNPKYEGENLIPRGTEIAQLYPDINKTRQVLITYYV
SSKDVTRLKQGQKTRLALTKVGNDQISIRGKINSIASAATTTKKGNVFKVTAKAKVSKKDSQTIKYGLQGKTITVVEKKT
FFDYYKDKLLNKNQK

Nucleotide

• Length: 1008 bp

>NTDB_id=1171337 DYB47_RS08360 WP_003080055.1 1664652..1665659(+) (comB) [Streptococcus macacae NCTC 11558]
ATGAACCCAAATTTATTTAAAAGCGCTGAATTCTACCGAAGACGCTATCATAATTTTGCTACAGTTCTTATTATTCCTTT
GGTTTGTTTACTTGTATTTTTATTTATCTTTCTATTATTTGCTAAAAAAGAGGTCACTGTCTTATCTAATGGCGAGATCT
CTCCCCTTAAAGTAATTGATGTTATTCAATCTAAAAGCGACTATCCCATTTCTGAAAATAATTTAACAGATAATCGCGCC
GTTAAAAAAGGGGATGTTCTCATCCAATATGTTAATCCAGCAGCAAATACAAGACAGGGCGGAAATAATCAGAATCAATC
TCAAAACAAGCAAAATAAGAATCAGCAGCAAAACAATAAGAATCAAAAGAACGGCAATCAAGGTCAAAAAAATCAAAATC
AGAACCAAAATAAAAAGGATCAGAAAAACAATAACCAATCTCAGCAAAACAAGCAAGGACAAAAGAAAACTAATCAATCC
CAAAATCAGCAGAATAAGAATCAAAATAAAAACCAATCTCAAAACAAACAAAATGGGAATCAAAACCAAAATAACTGGAA
TCAGAATAATCAAAATGATAAAGTCACAGCCAGCCAAGATGGTGTTATCCATACCAACCCCAAATATGAAGGTGAAAACT
TAATTCCTCGGGGGACTGAAATCGCACAGCTCTATCCAGATATTAACAAAACAAGACAAGTTCTGATCACTTATTACGTC
TCCTCTAAAGATGTCACCCGCCTCAAACAAGGCCAAAAGACTCGTCTTGCTTTAACCAAGGTAGGAAATGATCAAATTTC
CATTAGAGGAAAAATTAATAGTATCGCTTCAGCTGCTACAACGACGAAAAAAGGCAATGTCTTTAAAGTGACAGCTAAAG
CAAAAGTTTCTAAAAAAGACAGCCAAACCATTAAATACGGCCTCCAAGGTAAAACCATCACAGTTGTTGAAAAAAAGACT
TTCTTTGATTATTATAAAGATAAACTGTTAAATAAAAATCAAAAATAA

Domains

Predicted by InterproScan.

• HlyD family secretion protein (HlyD_3) (194-307)

3D structure

• AlphaFold DB: G5JUW9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB	Streptococcus mutans UA159	97.923	100	0.985
comB/nlmE	Streptococcus mutans UA159	51.205	99.104	0.507