Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   ACLV7W_RS10665 Genome accession   NZ_OZ217346
Coordinates   2187539..2188201 (-) Length   220 a.a.
NCBI ID   WP_004255321.1    Uniprot ID   A0A1E9GFS6
Organism   Streptococcus mitis isolate S. mitis D22     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2182539..2193201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7W_RS10640 (SMID22_21870) - 2182689..2182955 (-) 267 WP_001278169.1 Veg family protein -
  ACLV7W_RS10645 (SMID22_21880) dnaB 2182957..2184309 (-) 1353 WP_000852485.1 replicative DNA helicase -
  ACLV7W_RS10650 (SMID22_21890) rplI 2184353..2184805 (-) 453 WP_060627336.1 50S ribosomal protein L9 -
  ACLV7W_RS10655 (SMID22_21900) - 2184802..2186775 (-) 1974 WP_000715142.1 DHH family phosphoesterase -
  ACLV7W_RS10660 (SMID22_21910) hpf 2186911..2187459 (-) 549 WP_004255322.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ACLV7W_RS10665 (SMID22_21920) comFC/cflB 2187539..2188201 (-) 663 WP_004255321.1 ComF family protein Machinery gene
  ACLV7W_RS10670 (SMID22_21930) comFA/cflA 2188198..2189496 (-) 1299 WP_004255320.1 DEAD/DEAH box helicase Machinery gene
  ACLV7W_RS10675 (SMID22_21940) - 2189553..2190188 (+) 636 WP_411865918.1 YigZ family protein -
  ACLV7W_RS10680 - 2190282..2190377 (+) 96 Protein_2062 PH domain-containing protein -
  ACLV7W_RS10685 (SMID22_21950) cysK 2190474..2191400 (+) 927 WP_000029880.1 cysteine synthase A -
  ACLV7W_RS10690 (SMID22_21970) tsf 2191522..2192562 (-) 1041 WP_049499106.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25285.19 Da        Isoelectric Point: 6.0498

>NTDB_id=1170479 ACLV7W_RS10665 WP_004255321.1 2187539..2188201(-) (comFC/cflB) [Streptococcus mitis isolate S. mitis D22]
MKCLLCGQTMKAVLTFSSLLLLKNDDSCLCSDCDSTFERIGEENCPNCMKTGLSTKCQDCQFWCKEEVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASVLSEELKKYKEYQFVVIPLSPERLLERGFNQVEGLVEAAEFSLQDLLEKREERASSS
KNRSERLGTELPFFIKRGVTIPKKILLIDDIYTTGTTINRVKKLLEEAGAEDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1170479 ACLV7W_RS10665 WP_004255321.1 2187539..2188201(-) (comFC/cflB) [Streptococcus mitis isolate S. mitis D22]
ATGAAGTGCTTATTATGTGGGCAGACTATGAAGGCTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAAGAATGATGACTC
TTGTCTTTGTTCAGACTGTGACTCTACTTTTGAGAGGATTGGAGAAGAAAACTGCCCAAACTGTATGAAAACAGGTTTGT
CAACAAAGTGTCAAGATTGTCAATTTTGGTGTAAAGAAGAAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTTTTAAGAAAAGTTTTTGCTTCAGTTTTAAGTGA
GGAGTTAAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGAAAGATTGCTCGAGAGGGGATTTAACC
AGGTTGAAGGTTTAGTTGAAGCAGCAGAGTTCTCTTTGCAAGACTTACTAGAGAAGAGAGAAGAGCGGGCCAGTTCTTCC
AAAAATCGTTCAGAACGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGGGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGACATTTATACTACTGGAACAACTATAAATCGTGTGAAGAAGCTGTTGGAAGAAGCTGGTGCTGAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(180-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E9GFS6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis SK321

95

100

0.95
  comFC/cflB Streptococcus mitis NCTC 12261

93.182

100

0.932
  comFC/cflB Streptococcus pneumoniae TIGR4

92.273

100

0.923
  comFC/cflB Streptococcus pneumoniae Rx1

91.818

100

0.918
  comFC/cflB Streptococcus pneumoniae D39

91.818

100

0.918
  comFC/cflB Streptococcus pneumoniae R6

91.818

100

0.918
  comFC Bacillus subtilis subsp. subtilis str. 168

35.965

100

0.373

Multiple sequence alignment