Detailed information NTG1170411

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: ACLV7W_RS00210
• Genome accession: NZ_OZ217346
• Coordinates: 36570..38723 (+)
• Length: 717 a.a.
• NCBI ID: WP_411865221.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis D22
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 31570..43723

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7W_RS00175 (SMID22_00330)	recO	32447..33217 (+)	771	WP_411865219.1	DNA repair protein RecO	-
ACLV7W_RS00180 (SMID22_00340)	plsX	33214..34206 (+)	993	WP_411865220.1	phosphate acyltransferase PlsX	-
ACLV7W_RS00185 (SMID22_00350)	-	34212..34448 (+)	237	WP_000136444.1	acyl carrier protein	-
ACLV7W_RS00190 (SMID22_00360)	-	34893..35069 (+)	177	WP_125453304.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACLV7W_RS00195 (SMID22_00370)	-	35301..35471 (+)	171	WP_007522555.1	H354_08695 family bacteriocin-like peptide	-
ACLV7W_RS00200 (SMID22_00380)	-	35511..35690 (+)	180	WP_125453302.1	hypothetical protein	-
ACLV7W_RS00205 (SMID22_00390)	-	36069..36257 (+)	189	WP_000757184.1	hypothetical protein	-
ACLV7W_RS00210 (SMID22_00400)	comA	36570..38723 (+)	2154	WP_411865221.1	peptide cleavage/export ABC transporter ComA	Regulator
ACLV7W_RS00215 (SMID22_00410)	comB	38736..40085 (+)	1350	WP_045610806.1	competence pheromone export protein ComB	Regulator
ACLV7W_RS00220 (SMID22_00420)	purC	40255..40962 (+)	708	WP_045610807.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
ACLV7W_RS00225	-	40964..41107 (+)	144	WP_080890703.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80230.32 Da
• Isoelectric Point: 6.6494

>NTDB_id=1170411 ACLV7W_RS00210 WP_411865221.1 36570..38723(+) (comA) [Streptococcus mitis isolate S. mitis D22]
MKFGKRHYRPQVDQMDCGVASLAMIFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVTGQDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKDQKNGLLSFIPI
LVKQRGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHIFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVDYLKKSFTYSRAESQQKALKKVAHL
LLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSLM
KGDMTFKQVSYKYGYGRDVLSDINLTIPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKTLRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQKDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=1170411 ACLV7W_RS00210 WP_411865221.1 36570..38723(+) (comA) [Streptococcus mitis isolate S. mitis D22]
ATGAAATTTGGGAAACGTCACTATCGTCCGCAGGTGGATCAGATGGACTGCGGTGTAGCTTCATTGGCCATGATTTTTGG
CTACTATGGTAGTTACTATTCTTTGGCTCACTTGCGTGAATTAGCCAAGACGACCATGGATGGGACGACGGCTTTGGGCT
TGGTCAAGGTGGCAGAGGAGATTGGCTTTGAGACGCGAGCGATCAAGGCGGATATGACACTCTTTGACTTGCCAGATTTG
ACCTTTCCTTTTGTTGCCCATGTGCTTAAGGAAGGGAAATTGCTCCACTACTATGTGGTGACTGGGCAGGATAAGGACAG
CATTCATATTGCTGATCCAGATCCTGGGGTGAAATTGACCAAACTGCCACGTGAGCGTTTTGCGGAAGAATGGACAGGAG
TGACTCTGTTTATGGCACCTAGTCCAGACTACAAGCCTCATAAGGATCAAAAGAATGGCCTGCTTTCTTTTATCCCTATA
TTAGTGAAGCAGCGTGGCTTGATTGCCAATATCGTTTTGGCGACACTCTTGGTAACCTTGATTAATATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACCTATGTACCAGATCAGATGCGTTCGACGCTGGGGATCATTTCTATTGGGCTGGTGA
TTGTTTATATTCTTCAGCAGATCTTGTCTTACGCTCAGGAGTATCTCTTACTTGTTTTGGGGCAACGCCTGTCGATTGAC
GTGATTTTATCCTATATCAAGCATATTTTTCACCTGCCTATGTCCTTCTTTGCGACACGCAGAACAGGGGAAATCGTGTC
TCGTTTTACAGATGCTAACAGTATTATCGATGCGCTGGCTTCGACCATTCTTTCGATTTTCCTAGATGTGTCAACGGTTG
TCATTATTTCCCTTGTTTTATTTTCACAAAATACCAATCTCTTTTTCATGACTTTATTGGCACTTCCTATCTATACAGTG
ATTATCTTTGCCTTTATGAAGCCGTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATCGAGGACATCAACGGTATTGAGACTATCAAGTCCTTGACCAGTGAAAGTTCACGCTACCAAAAGATTGACAAGGAAT
TTGTGGATTATCTGAAAAAATCCTTTACCTATAGTCGAGCAGAGAGTCAGCAAAAGGCTCTGAAAAAAGTTGCCCATCTC
TTGCTCAATGTCGGCATTCTCTGGATGGGAGCTGTTCTGGTCATGGATGGCAAGATGAGTTTAGGGCAGTTGATTACCTA
TAATACCTTGCTTGTTTACTTTACAAATCCTTTGGAAAATATCATCAACCTACAAACCAAACTTCAGACAGCGCAGGTCG
CCAATAACCGTCTGAATGAGGTTTATCTGGTAGCTTCGGAGTTTGAGGAGAAGAAAACGGTTGAGGATTTGAGTTTGATG
AAGGGAGATATGACCTTCAAGCAGGTTTCCTACAAGTATGGCTATGGTCGAGACGTCTTGTCAGATATCAATTTGACCAT
TCCCCAAGGTTCTAAGGTGGCTTTTGTGGGGATTTCGGGGTCAGGTAAGACGACCTTGGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAGACTCTGCGCCAGTATATT
AACTATCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTCCTTGGAGCCAAGGAAGGGACGAC
TCAAAAGGATATCTTACGGGCGGTCGAATTGGCAGAGATTCGGGAGGACATTGAGCGCATGCCACTGAATTACCAGACAG
AATTGACTTCGGATGGGGCAGGGATCTCAGGTGGTCAACGTCAGAGAATTGCTCTGGCGCGTGCTCTCTTGACAGATGCG
CCGGTCTTGATTTTGGATGAGGCAACTAGCAGTTTGGATATTTTAACAGAGAAGCGGATTGTCGATAATCTCATGGCTTT
AGACAAGACCTTGATTTTCATTGCTCACCGCTTGACCATTGCAGAGCGGACAGAGAAGGTGGTTGTTTTGGATCAGGGCA
AGATTGTTGAAGAAGGAAAACATGCTGATTTGCTTGCACAGGGTGGTTTTTACGCACATTTGGTGAATAGCTAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-650)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	98.745	100	0.987
comA	Streptococcus mitis SK321	98.326	100	0.983
comA	Streptococcus pneumoniae Rx1	98.326	100	0.983
comA	Streptococcus pneumoniae D39	98.326	100	0.983
comA	Streptococcus pneumoniae R6	98.326	100	0.983
comA	Streptococcus pneumoniae TIGR4	97.908	100	0.979
comA	Streptococcus gordonii str. Challis substr. CH1	80.614	100	0.806
comA/nlmT	Streptococcus mutans UA159	65.132	100	0.651