Detailed information NTG1170394

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ACLV7D_RS09765
• Genome accession: NZ_OZ217345
• Coordinates: 2026107..2028260 (+)
• Length: 717 a.a.
• NCBI ID: WP_173283258.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis F22
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2021107..2033260

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7D_RS09735 (SMIF22_19280)	-	2021679..2022665 (-)	987	WP_218764732.1	rhodanese-related sulfurtransferase	-
ACLV7D_RS09740 (SMIF22_19290)	-	2022860..2024053 (-)	1194	WP_033680873.1	OFA family MFS transporter	-
ACLV7D_RS09745 (SMIF22_19300)	blpZ	2024592..2024840 (-)	249	WP_112444786.1	immunity protein BlpZ	-
ACLV7D_RS09750 (SMIF22_19310)	-	2024920..2025138 (-)	219	WP_173213201.1	hypothetical protein	-
ACLV7D_RS09755 (SMIF22_19320)	-	2025144..2025518 (-)	375	WP_173213199.1	immunity protein	-
ACLV7D_RS09760 (SMIF22_19330)	-	2025570..2025797 (-)	228	WP_164226314.1	Blp family class II bacteriocin	-
ACLV7D_RS09765 (SMIF22_19340)	comA/nlmT	2026107..2028260 (+)	2154	WP_173283258.1	peptide cleavage/export ABC transporter BlpA	Regulator
ACLV7D_RS09770 (SMIF22_19350)	-	2028271..2029632 (+)	1362	WP_218764733.1	bacteriocin secretion accessory protein	-
ACLV7D_RS09775 (SMIF22_19360)	blpC	2029689..2029829 (+)	141	WP_164226699.1	quorum-sensing system pheromone BlpC	-
ACLV7D_RS09780 (SMIF22_19370)	-	2029936..2031270 (-)	1335	WP_218764734.1	sensor histidine kinase	-
ACLV7D_RS09785 (SMIF22_19380)	comE/blpR	2031274..2032023 (-)	750	WP_164226697.1	response regulator transcription factor	Regulator
ACLV7D_RS09790 (SMIF22_19390)	-	2032020..2032367 (-)	348	WP_112444768.1	LytTR family DNA-binding domain-containing protein	-
ACLV7D_RS09795 (SMIF22_19400)	-	2032551..2032937 (+)	387	WP_225904842.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80792.85 Da
• Isoelectric Point: 7.9874

>NTDB_id=1170394 ACLV7D_RS09765 WP_173283258.1 2026107..2028260(+) (comA/nlmT) [Streptococcus mitis isolate S. mitis F22]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAANEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIGYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTILSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=1170394 ACLV7D_RS09765 WP_173283258.1 2026107..2028260(+) (comA/nlmT) [Streptococcus mitis isolate S. mitis F22]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAGGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCAAATGAAATGGGATTTGAAACAAGACCTGTTCAAGCAGATAAAACTCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTGGTTACATTGTTCTCTCAAGCTTATTGGTCACGATTATCAATATCGGTGGTTCTTA
TTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TAACCTATATCCTCCAGCAAGTCATGAGTTTCTCCCGAGATTATCTCCTAACTATTCTGAGTCAGAGATTAAGCATTGAT
GTGATTTTATCCTATATCCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCTATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATTGGTCAGCTGATTACCTT
TAACACACTTCTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTCAGTGGTTCTGGTAAAACAACTTTAGCAAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGACATATTTCCATCAATCATCAGGATATCAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAG
CCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCTCCT
GTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTCAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGA
AAATCATTGAAGTTGGTAGCCACCAAGAGTTAATGCAGGCTCAAGGTTTCTACCATCATCTATTCAACAAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.028	99.721	0.718
comA	Streptococcus mitis NCTC 12261	66.48	99.442	0.661
comA	Streptococcus pneumoniae Rx1	65.919	99.442	0.656
comA	Streptococcus pneumoniae R6	65.919	99.442	0.656
comA	Streptococcus pneumoniae D39	65.919	99.442	0.656
comA	Streptococcus mitis SK321	65.919	99.442	0.656
comA	Streptococcus gordonii str. Challis substr. CH1	65.32	100	0.654
comA	Streptococcus pneumoniae TIGR4	65.638	99.442	0.653