Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   ACLV7D_RS04710 Genome accession   NZ_OZ217345
Coordinates   984489..985337 (+) Length   282 a.a.
NCBI ID   WP_164226200.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis F22     
Function   ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology)   
DNA processing Competence regulation

Genomic Context

Location: 979489..990337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7D_RS04710 (SMIF22_09250) dprA/cilB/dalA 984489..985337 (+) 849 WP_164226200.1 DNA-processing protein DprA Machinery gene
  ACLV7D_RS04715 - 985932..986084 (+) 153 WP_031222468.1 hypothetical protein -
  ACLV7D_RS04720 (SMIF22_09260) - 986153..987196 (+) 1044 WP_050083959.1 TIGR00341 family protein -
  ACLV7D_RS04725 (SMIF22_09270) topA 987362..989449 (+) 2088 WP_173269656.1 type I DNA topoisomerase -
  ACLV7D_RS04730 - 989547..989693 (+) 147 WP_000693333.1 hypothetical protein -
  ACLV7D_RS04735 (SMIF22_09280) - 989706..990065 (+) 360 WP_001237210.1 YbaN family protein -

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31066.72 Da        Isoelectric Point: 5.4047

>NTDB_id=1170368 ACLV7D_RS04710 WP_164226200.1 984489..985337(+) (dprA/cilB/dalA) [Streptococcus mitis isolate S. mitis F22]
MKITNYEIYKLKKSGLTNQQVLKVLEYGENFDQELLLGDIADISGCRNPAVFMERYFQIDDAHLEKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEG
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide


Download         Length: 849 bp        

>NTDB_id=1170368 ACLV7D_RS04710 WP_164226200.1 984489..985337(+) (dprA/cilB/dalA) [Streptococcus mitis isolate S. mitis F22]
ATGAAAATCACAAACTATGAAATCTATAAGTTGAAAAAATCAGGTTTGACCAATCAACAGGTTTTGAAGGTCCTAGAATA
TGGCGAAAATTTCGATCAAGAACTGTTGTTAGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGGAGAAGGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGACGACTGT
TATCCTTGGGATTTGAGTGAAATATACGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCTTGAAATTCCC
GAAGGTAGCGGTTGTGGGTAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAGGGCTTGGAAA
ATGAACTAGTTATCGTCAGTGGATTAGCCAAGGGGATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGGACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGTTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTTAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGCGTGATTGTAGCAGAGGCCAAGATGCGCTCAGGTAGTCTTATTACCTGTGAGAGAGCAATGGAAGGA
GGGCGTGATGTTTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGGGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

98.582

100

0.986
  dprA/cilB/dalA Streptococcus pneumoniae D39

98.582

100

0.986
  dprA/cilB/dalA Streptococcus pneumoniae R6

98.582

100

0.986
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

98.582

100

0.986
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

98.582

100

0.986
  dprA/cilB/dalA Streptococcus mitis SK321

97.163

100

0.972
  dprA Streptococcus mutans UA159

62.5

99.291

0.621
  dprA Lactococcus lactis subsp. cremoris KW2

55.714

99.291

0.553
  dprA Haemophilus influenzae Rd KW20

38.202

94.681

0.362

Multiple sequence alignment