Detailed information NTG1170330

Bioinformatically predicted

Overview

• Name: comB
• Type: Regulator
• Locus tag: ACLV7D_RS00295
• Genome accession: NZ_OZ217345
• Coordinates: 52910..54259 (+)
• Length: 449 a.a.
• NCBI ID: WP_218764150.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis F22
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 47910..59259

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7D_RS00255 (SMIF22_00460)	-	48339..48467 (+)	129	WP_000658224.1	smi_0059.1 family bacteriocin-like peptide	-
ACLV7D_RS00260 (SMIF22_00470)	-	48479..48634 (+)	156	WP_001004584.1	hypothetical protein	-
ACLV7D_RS00265 (SMIF22_00480)	-	48669..48845 (+)	177	WP_000180820.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ACLV7D_RS00270 (SMIF22_00500)	-	49077..49247 (+)	171	WP_000067699.1	H354_08695 family bacteriocin-like peptide	-
ACLV7D_RS00275 (SMIF22_00510)	-	49287..49466 (+)	180	WP_033675650.1	hypothetical protein	-
ACLV7D_RS00280 (SMIF22_00520)	-	49545..49751 (+)	207	WP_173219508.1	bacteriocin immunity protein	-
ACLV7D_RS00285 (SMIF22_00530)	-	50246..50434 (+)	189	WP_033680983.1	hypothetical protein	-
ACLV7D_RS00290 (SMIF22_00540)	comA	50744..52897 (+)	2154	WP_218764149.1	peptide cleavage/export ABC transporter ComA	Regulator
ACLV7D_RS00295 (SMIF22_00550)	comB	52910..54259 (+)	1350	WP_218764150.1	competence pheromone export protein ComB	Regulator
ACLV7D_RS00300 (SMIF22_00560)	purC	54429..55136 (+)	708	WP_218764151.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
ACLV7D_RS00305	-	55138..55281 (+)	144	WP_119946632.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
ACLV7D_RS00310 (SMIF22_00570)	-	55338..59063 (+)	3726	WP_218764152.1	phosphoribosylformylglycinamidine synthase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 49822.76 Da
• Isoelectric Point: 5.5749

>NTDB_id=1170330 ACLV7D_RS00295 WP_218764150.1 52910..54259(+) (comB) [Streptococcus mitis isolate S. mitis F22]
MKPEFLESAEFYNRRYHNFSSRVIVPMSLLLVFLLGFATFAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGELLVQYQEGAEGVQAEAYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYLSQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYKSQGEENPQAKSQAVAQVEAQLS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLDQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSTMVAEGALLAQLYPSLEKEGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAKNQLFLDSTITSIDTTATKTEK
GNFFKIEAETTLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide

• Length: 1350 bp

>NTDB_id=1170330 ACLV7D_RS00295 WP_218764150.1 52910..54259(+) (comB) [Streptococcus mitis isolate S. mitis F22]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTGTACCCAT
GTCCCTTCTGCTTGTGTTTTTACTTGGATTTGCAACATTTGCAGAGAAGGAGATGAGTTTGTCTACTAGAGCTACTGTCG
AGCCTAGTCGAATCCTTGCAAATATCCAGTCAACTAGCAACAATCGCATTCTTGTCAATCATCTGGAAGAAAATAAGCTG
GTTAAAAAGGGAGAACTGTTGGTTCAATATCAGGAAGGGGCGGAGGGTGTCCAAGCGGAGGCCTATGCTAGTCAGTTGGA
CATGCTCAAGGATCAAAAAAAGCAATTGGAGTATTTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACCTCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGCCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATGGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTACTCTCTCT
ACCAGTCTTATAAGTCTCAGGGTGAGGAAAATCCGCAAGCTAAATCCCAGGCAGTTGCGCAGGTTGAAGCACAGCTTTCT
CAGTTAGAATCCAGTCTTGCTACTTACCGTGTTCAGTATGCGGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGCTTAAG
CAGTCAATTGGAGTCCCTTAAATCCCAACACTTAGCAAAGGTTGGTCAGGAATTGACCCTTCTAGACCAGAAAATATTGG
AGGCAGAGTCGGGTAAGAAGGTTCAGGGGAATCTTCTAGATAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGACTCTACCATGGTAGCAGAAGGCGCCTTACTAGCCCAACTCTATCCGTCCTTGGAAAAAGA
AGGAAAAGCCAAACTAACAGCTTATCTTAGTTCAAAAGATGTAGCAAGGATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCAAGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATACGACAGCTACTAAGACTGAAAAA
GGGAATTTCTTTAAAATTGAGGCGGAAACTACTCTAACTTCGGAGCAGGCTGAAAAACTTCGGTATGGGGTGGAAGGTCG
CCTGCAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB	Streptococcus mitis SK321	96.882	100	0.969
comB	Streptococcus pneumoniae TIGR4	95.768	100	0.958
comB	Streptococcus mitis NCTC 12261	95.768	100	0.958
comB	Streptococcus pneumoniae R6	95.546	100	0.955
comB	Streptococcus pneumoniae Rx1	95.546	100	0.955
comB	Streptococcus pneumoniae D39	95.546	100	0.955
comB	Streptococcus gordonii str. Challis substr. CH1	55.778	100	0.559