Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   ACLV7A_RS09770 Genome accession   NZ_OZ217344
Coordinates   2051849..2052511 (-) Length   220 a.a.
NCBI ID   WP_411864187.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis E22     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2046849..2057511
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7A_RS09750 (SMIE22_19520) - 2047365..2048543 (-) 1179 WP_411864186.1 acetyl-CoA C-acetyltransferase -
  ACLV7A_RS09755 (SMIE22_19530) - 2048561..2049406 (-) 846 WP_050242833.1 3-hydroxybutyryl-CoA dehydrogenase -
  ACLV7A_RS09760 (SMIE22_19540) - 2049488..2050696 (-) 1209 WP_050242834.1 acyl-CoA dehydrogenase family protein -
  ACLV7A_RS09765 (SMIE22_19550) hpf 2051221..2051769 (-) 549 WP_050073478.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ACLV7A_RS09770 (SMIE22_19560) comFC/cflB 2051849..2052511 (-) 663 WP_411864187.1 ComF family protein Machinery gene
  ACLV7A_RS09775 (SMIE22_19570) comFA/cflA 2052508..2053806 (-) 1299 WP_411864188.1 DEAD/DEAH box helicase Machinery gene
  ACLV7A_RS09780 (SMIE22_19580) - 2053863..2054498 (+) 636 WP_411864189.1 YigZ family protein -
  ACLV7A_RS09785 - 2054592..2054687 (+) 96 Protein_1892 PH domain-containing protein -
  ACLV7A_RS09790 (SMIE22_19590) cysK 2054784..2055710 (+) 927 WP_411864190.1 cysteine synthase A -
  ACLV7A_RS09795 (SMIE22_19610) tsf 2055832..2056872 (-) 1041 WP_000808091.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25307.38 Da        Isoelectric Point: 8.3145

>NTDB_id=1170319 ACLV7A_RS09770 WP_411864187.1 2051849..2052511(-) (comFC/cflB) [Streptococcus mitis isolate S. mitis E22]
MKCLLCGQTMKAVLTFSSLLLLKNDASCLCLDCDSTFERIGEEYCPNCMKIGLSTKCQDCQFWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFSSFLSEELKKYKEYQFVVIPLSKERYADRGFNQVEGLVNAAGFKYLDLLEKREERASSS
KSRSERLATELPFFIKSGVRIPKKILLIDDIYTTGTTINRVKKLLEEAGAEDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1170319 ACLV7A_RS09770 WP_411864187.1 2051849..2052511(-) (comFC/cflB) [Streptococcus mitis isolate S. mitis E22]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGGCTGTTTTAACTTTCAGTAGTCTCTTACTTCTGAAGAATGATGCCTC
CTGTCTTTGTTTAGATTGTGATTCTACTTTTGAGAGAATTGGAGAAGAGTACTGTCCAAACTGTATGAAAATAGGATTGT
CAACAAAGTGTCAAGATTGTCAATTTTGGTGTAAAGAAGGAGTTGAGGTCAGTCATAGAGCGATTTTCACTTACAATCAA
GCTATGAAGGATTTTTTTAGTCGATATAAATTTGATGGTGACTTCCTTTTAAGAAAAGTTTTTTCCTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTACCAATTTGTAGTCATTCCATTAAGTAAGGAGAGATATGCTGATAGAGGATTTAATC
AGGTTGAGGGCTTGGTCAATGCAGCAGGATTTAAGTACCTGGATTTGTTAGAGAAAAGAGAAGAACGAGCCAGTTCTTCT
AAAAGTCGCTCAGAGCGCTTGGCGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCCGCATTCCTAAGAAAATCCTACT
TATAGATGATATTTATACTACAGGAACAACTATAAATCGTGTGAAGAAACTGCTGGAAGAAGCTGGTGCTGAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(157-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis NCTC 12261

92.273

100

0.923
  comFC/cflB Streptococcus pneumoniae TIGR4

91.364

100

0.914
  comFC/cflB Streptococcus pneumoniae R6

90.909

100

0.909
  comFC/cflB Streptococcus pneumoniae D39

90.909

100

0.909
  comFC/cflB Streptococcus pneumoniae Rx1

90.909

100

0.909
  comFC/cflB Streptococcus mitis SK321

89.545

100

0.895
  comFC Bacillus subtilis subsp. subtilis str. 168

35.088

100

0.364

Multiple sequence alignment