Detailed information NTG1170312

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ACLV7A_RS09455
• Genome accession: NZ_OZ217344
• Coordinates: 1951218..1953371 (+)
• Length: 717 a.a.
• NCBI ID: WP_411864157.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis E22
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1946218..1958371

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7A_RS09425 (SMIE22_18830)	-	1946789..1947775 (-)	987	WP_261013052.1	rhodanese-related sulfurtransferase	-
ACLV7A_RS09430 (SMIE22_18840)	-	1947971..1949164 (-)	1194	WP_411864156.1	OFA family MFS transporter	-
ACLV7A_RS09435 (SMIE22_18850)	blpZ	1949703..1949951 (-)	249	WP_112444786.1	immunity protein BlpZ	-
ACLV7A_RS09440 (SMIE22_18860)	-	1950031..1950249 (-)	219	WP_173213201.1	hypothetical protein	-
ACLV7A_RS09445 (SMIE22_18870)	-	1950255..1950629 (-)	375	WP_173213199.1	immunity protein	-
ACLV7A_RS09450 (SMIE22_18880)	-	1950681..1950908 (-)	228	WP_164226314.1	Blp family class II bacteriocin	-
ACLV7A_RS09455 (SMIE22_18890)	comA/nlmT	1951218..1953371 (+)	2154	WP_411864157.1	peptide cleavage/export ABC transporter BlpA	Regulator
ACLV7A_RS09460 (SMIE22_18900)	-	1953382..1954743 (+)	1362	WP_411864158.1	bacteriocin secretion accessory protein	-
ACLV7A_RS09465 (SMIE22_18910)	blpC	1954800..1954940 (+)	141	WP_173249818.1	quorum-sensing system pheromone BlpC	-
ACLV7A_RS09470 (SMIE22_18920)	-	1955047..1956381 (-)	1335	WP_218757325.1	sensor histidine kinase	-
ACLV7A_RS09475 (SMIE22_18930)	comE/blpR	1956385..1957134 (-)	750	WP_173253425.1	response regulator transcription factor	Regulator
ACLV7A_RS09480 (SMIE22_18940)	-	1957131..1957478 (-)	348	WP_112444768.1	LytTR family DNA-binding domain-containing protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80822.79 Da
• Isoelectric Point: 7.4329

>NTDB_id=1170312 ACLV7A_RS09455 WP_411864157.1 1951218..1953371(+) (comA/nlmT) [Streptococcus mitis isolate S. mitis E22]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNDLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMRSTLGIISVGLVITYILQQVMGFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQAPENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGSGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=1170312 ACLV7A_RS09455 WP_411864157.1 1951218..1953371(+) (comA/nlmT) [Streptococcus mitis isolate S. mitis E22]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCTAGAGACTGCGGTGTTGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGAACGACTGCCCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGATCTACTAAGCTTCCTTCCTCTG
ATTTTCAAGCAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTA
TTATCTCCAAGGAATCTTGGATGAATACATCCCAAATCAGATGAGATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TCACCTATATCCTCCAACAAGTCATGGGTTTCTCCAGAGATTATCTCCTAACTGTTCTGAGTCAGAGATTAAGCATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGGGGAGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAACTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGTGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTCTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAGTTCCAAGCCCCAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTCAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGACATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCTCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAG
CCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGATCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAATCTCCT
GTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTCAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGA
AAATCATTGAAGTGGGTAGTCATCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-649)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.748	99.721	0.715
comA	Streptococcus mitis NCTC 12261	66.339	99.442	0.66
comA	Streptococcus mitis SK321	65.778	99.442	0.654
comA	Streptococcus pneumoniae Rx1	65.778	99.442	0.654
comA	Streptococcus pneumoniae D39	65.778	99.442	0.654
comA	Streptococcus pneumoniae R6	65.778	99.442	0.654
comA	Streptococcus pneumoniae TIGR4	65.498	99.442	0.651
comA	Streptococcus gordonii str. Challis substr. CH1	64.763	100	0.649