Detailed information NTG1170222

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ACLV7Z_RS08415
• Genome accession: NZ_OZ217343
• Coordinates: 1684329..1686482 (+)
• Length: 717 a.a.
• NCBI ID: WP_218774476.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis G22
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1679329..1691482

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7Z_RS08380 (SMIG22_16500)	ccrZ	1679645..1680439 (-)	795	WP_218774479.1	cell cycle regulator CcrZ	-
ACLV7Z_RS08385	-	1680601..1680756 (-)	156	Protein_1604	type II CAAX prenyl endopeptidase Rce1 family protein	-
ACLV7Z_RS08390 (SMIG22_16530)	-	1681453..1681662 (-)	210	WP_176139343.1	Blp family class II bacteriocin	-
ACLV7Z_RS08395 (SMIG22_16540)	-	1681678..1681926 (-)	249	WP_176139344.1	Blp family class II bacteriocin	-
ACLV7Z_RS08400 (SMIG22_16550)	-	1682184..1683221 (-)	1038	WP_218774478.1	thioredoxin domain-containing protein	-
ACLV7Z_RS08405 (SMIG22_16560)	-	1683387..1683791 (-)	405	WP_218774477.1	immunity protein	-
ACLV7Z_RS08410 (SMIG22_16570)	-	1683811..1684047 (-)	237	WP_050390361.1	Blp family class II bacteriocin	-
ACLV7Z_RS08415 (SMIG22_16580)	comA/nlmT	1684329..1686482 (+)	2154	WP_218774476.1	peptide cleavage/export ABC transporter BlpA	Regulator
ACLV7Z_RS08420 (SMIG22_16590)	-	1686493..1687854 (+)	1362	WP_218774475.1	bacteriocin secretion accessory protein	-
ACLV7Z_RS08425 (SMIG22_16600)	blpC	1687911..1688066 (+)	156	WP_218774474.1	quorum-sensing system pheromone BlpC	-
ACLV7Z_RS08430 (SMIG22_16610)	-	1688109..1689449 (-)	1341	WP_218774473.1	sensor histidine kinase	-
ACLV7Z_RS08435 (SMIG22_16620)	comE/blpR	1689463..1690200 (-)	738	WP_218774472.1	response regulator transcription factor	Regulator
ACLV7Z_RS08440 (SMIG22_16630)	-	1690205..1690543 (-)	339	WP_150922867.1	LytTR family DNA-binding domain-containing protein	-
ACLV7Z_RS08445 (SMIG22_16640)	-	1690902..1691153 (+)	252	WP_001130045.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80718.72 Da
• Isoelectric Point: 7.6966

>NTDB_id=1170222 ACLV7Z_RS08415 WP_218774476.1 1684329..1686482(+) (comA/nlmT) [Streptococcus mitis isolate S. mitis G22]
MTSYKHTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLVIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMRSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFL
MGDIAFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILKACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=1170222 ACLV7Z_RS08415 WP_218774476.1 1684329..1686482(+) (comA/nlmT) [Streptococcus mitis isolate S. mitis G22]
ATGACTTCTTATAAACATACATTTGTTCCTCAAATAGATGCGAGAGACTGCGGTGTTGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAAACCAATAAAGAAGGAACAACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGGTTATTGGTGATCCTGACCCTTCTGTAAAAATCACCAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGCCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTAGTCACGATTATCAATATAGGTGGTTCTTA
TTATCTCCAAGGAATCTTGGATGAATACATCCCAAATCAGATGAGATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGGGGAGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAGTATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTCTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTTG
CTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGCATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTCAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGACATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATC
AATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAATTTAACTTTGGGCGGTAATCATATGATTAG
CCAAGAAGATATTCTAAAAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAACAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCTCCT
GTTTTAATACTAGACGAAGCCACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGGGGA
AAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTGTTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-649)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.011	99.163	0.714
comA	Streptococcus mitis NCTC 12261	66.48	99.442	0.661
comA	Streptococcus pneumoniae Rx1	65.919	99.442	0.656
comA	Streptococcus pneumoniae D39	65.919	99.442	0.656
comA	Streptococcus pneumoniae R6	65.919	99.442	0.656
comA	Streptococcus mitis SK321	65.919	99.442	0.656
comA	Streptococcus pneumoniae TIGR4	65.638	99.442	0.653
comA	Streptococcus gordonii str. Challis substr. CH1	65.042	100	0.651