Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ACLV7Z_RS08435 Genome accession   NZ_OZ217343
Coordinates   1689463..1690200 (-) Length   245 a.a.
NCBI ID   WP_218774472.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis G22     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1684463..1695200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Z_RS08420 (SMIG22_16590) - 1686493..1687854 (+) 1362 WP_218774475.1 bacteriocin secretion accessory protein -
  ACLV7Z_RS08425 (SMIG22_16600) blpC 1687911..1688066 (+) 156 WP_218774474.1 quorum-sensing system pheromone BlpC -
  ACLV7Z_RS08430 (SMIG22_16610) - 1688109..1689449 (-) 1341 WP_218774473.1 sensor histidine kinase -
  ACLV7Z_RS08435 (SMIG22_16620) comE/blpR 1689463..1690200 (-) 738 WP_218774472.1 response regulator transcription factor Regulator
  ACLV7Z_RS08440 (SMIG22_16630) - 1690205..1690543 (-) 339 WP_150922867.1 LytTR family DNA-binding domain-containing protein -
  ACLV7Z_RS08445 (SMIG22_16640) - 1690902..1691153 (+) 252 WP_001130045.1 hypothetical protein -
  ACLV7Z_RS08450 (SMIG22_16650) - 1691182..1691505 (+) 324 WP_000131861.1 hypothetical protein -
  ACLV7Z_RS08455 (SMIG22_16660) - 1691568..1692617 (-) 1050 WP_218774471.1 ABC transporter permease -
  ACLV7Z_RS08460 (SMIG22_16670) pptA 1692614..1693345 (-) 732 WP_218774470.1 ABC transporter ATP-binding protein Regulator
  ACLV7Z_RS08465 (SMIG22_16680) - 1693413..1693823 (+) 411 WP_001278317.1 HIT family protein -
  ACLV7Z_RS08470 (SMIG22_16690) - 1693833..1694120 (+) 288 WP_218774469.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28792.85 Da        Isoelectric Point: 5.7987

>NTDB_id=1170223 ACLV7Z_RS08435 WP_218774472.1 1689463..1690200(-) (comE/blpR) [Streptococcus mitis isolate S. mitis G22]
MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSRFAQFQYPFKEVYY
LETSPKSHHVILYTETDRLEFTASLEEILKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEV
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1170223 ACLV7Z_RS08435 WP_218774472.1 1689463..1690200(-) (comE/blpR) [Streptococcus mitis isolate S. mitis G22]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAGACTAGGATTGAAACGACGATTGAGAAACTCTTGAAAGAACA
TCATATTACTCCGAGTTCTTTTGAAGTTTTTGGTAAGCCAGACCAACTGCTAGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAAGGCCTAGAGGTGGCTAGAAAGATTCGGGATCGGGAT
CCTTATGCTCTGATTGTCTTTGTGACGACTCACTCAGAGTTTATGCCCCTGTCCTTCCGCTACCAAGTGTCTGCTTTGGA
CTACATTGATAAGGCCTTGTCAGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTTCTCTATGCCAATAGTCAAGATA
GTAAAAGTCTGGCGGAAGATTGCTTTTATTTTAAATCAAGATTTGCTCAATTTCAGTATCCTTTTAAAGAAGTTTACTAT
CTCGAAACGTCGCCCAAATCTCATCATGTCATTCTCTATACCGAGACGGACAGACTGGAATTTACAGCGAGTTTAGAGGA
GATTCTCAAGCAGGAGCCTCGTCTCCTGCAGTGCCATCGCTCTTTTCTTATCAATCCAGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGCTGTCTAATTGCGCGTTATAAGGTCAGGGAAGTGTCTGAAGTT
ATCAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

55.144

99.184

0.547
  comE/comE1 Streptococcus equinus JB1

42.194

96.735

0.408
  comE/comE2 Streptococcus equinus JB1

37.603

98.776

0.371

Multiple sequence alignment