Detailed information NTG1170205

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: ACLV7Z_RS04615
• Genome accession: NZ_OZ217343
• Coordinates: 937400..938248 (+)
• Length: 282 a.a.
• NCBI ID: WP_218774811.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis G22
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 932400..943248

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7Z_RS04590 (SMIG22_08960)	-	933123..933830 (+)	708	WP_000638495.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
ACLV7Z_RS04595 (SMIG22_08970)	-	933835..934857 (+)	1023	WP_218774809.1	ribitol-5-phosphate dehydrogenase	-
ACLV7Z_RS04600 (SMIG22_08980)	licA	934874..935743 (+)	870	WP_218774810.1	choline kinase LicA	-
ACLV7Z_RS04605 (SMIG22_08990)	-	935733..936611 (+)	879	WP_000791830.1	DMT family transporter	-
ACLV7Z_RS04610 (SMIG22_09000)	-	936623..937312 (+)	690	WP_000643974.1	sugar phosphate nucleotidyltransferase	-
ACLV7Z_RS04615 (SMIG22_09010)	dprA/cilB/dalA	937400..938248 (+)	849	WP_218774811.1	DNA-processing protein DprA	Machinery gene
ACLV7Z_RS04620 (SMIG22_09020)	-	938844..938969 (+)	126	WP_280630513.1	hypothetical protein	-
ACLV7Z_RS04625 (SMIG22_09030)	-	939022..940065 (+)	1044	WP_218774812.1	TIGR00341 family protein	-
ACLV7Z_RS04630 (SMIG22_09040)	topA	940231..942318 (+)	2088	WP_218774813.1	type I DNA topoisomerase	-
ACLV7Z_RS04635	-	942416..942562 (+)	147	WP_000693333.1	hypothetical protein	-
ACLV7Z_RS04640 (SMIG22_09050)	-	942575..942934 (+)	360	WP_050083961.1	YbaN family protein	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31118.79 Da
• Isoelectric Point: 5.2107

>NTDB_id=1170205 ACLV7Z_RS04615 WP_218774811.1 937400..938248(+) (dprA/cilB/dalA) [Streptococcus mitis isolate S. mitis G22]
MKITNYEIYKLKKSGLTNQQILNVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLEKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKAAVVGSRACSKQGAKSVEKIIQGLENELVIVSGLAKGIDTAAHMAVLQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGKDILAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=1170205 ACLV7Z_RS04615 WP_218774811.1 937400..938248(+) (dprA/cilB/dalA) [Streptococcus mitis isolate S. mitis G22]
ATGAAAATCACAAACTATGAAATCTATAAATTGAAAAAATCAGGTTTGACCAATCAACAGATTTTGAATGTCCTAGAATA
CGGTGAAAATGTCGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGAAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGGAGAAGGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGACGACTGT
TACCCTTGGGATTTGAGTGAAATATACGATGCACCTGTGCTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGCAGCAGTCGTAGGAAGTCGCGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAATTATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGCTTAGCCAAGGGTATCGATACAGCAGCTCATATGGCAGTTCTTCAAAATGGTGGAAAA
ACCATTGCAGTGATTGGAACAGGTCTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTATATTGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACCTGTGAGCGAGCAATGGAGGAA
GGGCGCGATGTTTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTTACAAGTGGGAAGGATATTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	97.518	100	0.975
dprA/cilB/dalA	Streptococcus pneumoniae D39	97.518	100	0.975
dprA/cilB/dalA	Streptococcus pneumoniae R6	97.518	100	0.975
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	97.518	100	0.975
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	97.163	100	0.972
dprA/cilB/dalA	Streptococcus mitis SK321	96.809	100	0.968
dprA	Streptococcus mutans UA159	64.286	99.291	0.638
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Haemophilus influenzae Rd KW20	39.326	94.681	0.372