Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   ACLV65_RS10115 Genome accession   NZ_OZ217342
Coordinates   2064715..2065377 (-) Length   220 a.a.
NCBI ID   WP_411865179.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis B22     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2059715..2070377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV65_RS10095 (SMIB22_19920) - 2060229..2061407 (-) 1179 WP_411865176.1 acetyl-CoA C-acetyltransferase -
  ACLV65_RS10100 (SMIB22_19930) - 2061425..2062270 (-) 846 WP_411865177.1 3-hydroxybutyryl-CoA dehydrogenase -
  ACLV65_RS10105 (SMIB22_19940) - 2062352..2063560 (-) 1209 WP_050242834.1 acyl-CoA dehydrogenase family protein -
  ACLV65_RS10110 (SMIB22_19950) hpf 2064087..2064635 (-) 549 WP_411865178.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ACLV65_RS10115 (SMIB22_19960) comFC/cflB 2064715..2065377 (-) 663 WP_411865179.1 ComF family protein Machinery gene
  ACLV65_RS10120 (SMIB22_19970) comFA/cflA 2065374..2066672 (-) 1299 WP_411865180.1 DEAD/DEAH box helicase Machinery gene
  ACLV65_RS10125 (SMIB22_19980) - 2066729..2067364 (+) 636 WP_411865181.1 YigZ family protein -
  ACLV65_RS10130 (SMIB22_19990) cysK 2067650..2068576 (+) 927 WP_000029881.1 cysteine synthase A -
  ACLV65_RS10135 (SMIB22_20010) tsf 2068698..2069738 (-) 1041 WP_173234333.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25276.23 Da        Isoelectric Point: 7.3688

>NTDB_id=1170154 ACLV65_RS10115 WP_411865179.1 2064715..2065377(-) (comFC/cflB) [Streptococcus mitis isolate S. mitis B22]
MKCLLCEQTMKTVLTFSSLLLLKNGASCLCLDCDSTFERIGEENCPNCMKIGLSTKCQDCQFWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFSSFLSEELKKYKEYQFVVIPLSKERYADRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLATELPFFVKSGVTIPKKILLIDDIYTTGTTINRVKKLLEEAGAEDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1170154 ACLV65_RS10115 WP_411865179.1 2064715..2065377(-) (comFC/cflB) [Streptococcus mitis isolate S. mitis B22]
ATGAAGTGCTTGTTATGTGAGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAAGAATGGTGCCTC
CTGTCTTTGTTTAGATTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAACTGTATGAAAATAGGATTGT
CAACAAAGTGTCAAGATTGTCAATTTTGGTGTAAGGAAGGAGTTGAGGTCAGTCATAGAGCGATTTTCACTTACAATCAA
GCTATGAAGGATTTTTTTAGTCGATATAAATTTGATGGAGACTTCCTTTTAAGAAAAGTTTTTTCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTACCAATTTGTAGTCATTCCATTAAGTAAGGAGAGATATGCTGATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAATATCTGGATTTATTAGAGAAAAGAGAAGAGCGGGCCAGTTCTTCC
AAAAATCGTTCAGAACGCTTGGCAACAGAACTTCCTTTCTTTGTCAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACTGGAACAACTATAAATCGTGTGAAGAAACTGTTGGAAGAAGCTGGTGCTGAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(150-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

92.727

100

0.927
  comFC/cflB Streptococcus pneumoniae Rx1

92.273

100

0.923
  comFC/cflB Streptococcus pneumoniae D39

92.273

100

0.923
  comFC/cflB Streptococcus pneumoniae R6

92.273

100

0.923
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

89.545

100

0.895
  comFC Bacillus subtilis subsp. subtilis str. 168

35.088

100

0.364

Multiple sequence alignment