Detailed information NTG1170065

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ACLV7Q_RS09795
• Genome accession: NZ_OZ217341
• Coordinates: 2019753..2021906 (+)
• Length: 717 a.a.
• NCBI ID: WP_411866009.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis C22
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2014753..2026906

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7Q_RS09765 (SMIC22_19320)	-	2015324..2016310 (-)	987	WP_175880376.1	rhodanese-related sulfurtransferase	-
ACLV7Q_RS09770 (SMIC22_19330)	-	2016506..2017699 (-)	1194	WP_218757233.1	OFA family MFS transporter	-
ACLV7Q_RS09775 (SMIC22_19340)	blpZ	2018238..2018486 (-)	249	WP_112444786.1	immunity protein BlpZ	-
ACLV7Q_RS09780 (SMIC22_19350)	-	2018566..2018784 (-)	219	WP_173213201.1	hypothetical protein	-
ACLV7Q_RS09785 (SMIC22_19360)	-	2018790..2019164 (-)	375	WP_173213199.1	immunity protein	-
ACLV7Q_RS09790 (SMIC22_19370)	-	2019216..2019443 (-)	228	WP_173220077.1	Blp family class II bacteriocin	-
ACLV7Q_RS09795 (SMIC22_19380)	comA/nlmT	2019753..2021906 (+)	2154	WP_411866009.1	peptide cleavage/export ABC transporter BlpA	Regulator
ACLV7Q_RS09800 (SMIC22_19390)	-	2021917..2023278 (+)	1362	WP_193550504.1	bacteriocin secretion accessory protein	-
ACLV7Q_RS09805 (SMIC22_19400)	blpC	2023335..2023475 (+)	141	WP_112444774.1	quorum-sensing system pheromone BlpC	-
ACLV7Q_RS09810 (SMIC22_19410)	-	2023582..2024916 (-)	1335	WP_218757325.1	sensor histidine kinase	-
ACLV7Q_RS09815 (SMIC22_19420)	comE/blpR	2024920..2025669 (-)	750	WP_173253425.1	response regulator transcription factor	Regulator
ACLV7Q_RS09820 (SMIC22_19430)	-	2025666..2026013 (-)	348	WP_218757326.1	LytTR family transcriptional regulator DNA-binding domain-containing protein	-
ACLV7Q_RS09825 (SMIC22_19440)	-	2026197..2026583 (+)	387	WP_225904702.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80759.82 Da
• Isoelectric Point: 7.6798

>NTDB_id=1170065 ACLV7Q_RS09795 WP_411866009.1 2019753..2021906(+) (comA/nlmT) [Streptococcus mitis isolate S. mitis C22]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLVIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
IFKQKSLIAYIVLSSLLITIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWLGAQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=1170065 ACLV7Q_RS09795 WP_411866009.1 2019753..2021906(+) (comA/nlmT) [Streptococcus mitis isolate S. mitis C22]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCTAGAGACTGCGGTGTTGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGAACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGGTTATTGGTGATCCTGACCCTTCTGTAAAAATCACCAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCTAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGATCACTATTATCAATATCGGTGGTTCTTA
TTATCTCCAAGGAATCTTGGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGA
TTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCTATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
CATTGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTAGAAAAATCCTTTAAGCTCAGTAAGTATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGCTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTCTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTTG
CTAATAACCGTTTGAACGAGGTCTATTTAGTCGAATCTGAATTTCAAGTTCAAGAAAATCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTCAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCTTACAAAGGACATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGATTAG
CCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCCGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTAGCTCGTGCTCTTTTAACTAAAGCTCCT
GTTCTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGGGGA
AAATCATTGAAGTTGGTAGTCATCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	71.888	99.721	0.717
comA	Streptococcus mitis NCTC 12261	66.62	99.442	0.662
comA	Streptococcus pneumoniae Rx1	66.059	99.442	0.657
comA	Streptococcus pneumoniae R6	66.059	99.442	0.657
comA	Streptococcus pneumoniae D39	66.059	99.442	0.657
comA	Streptococcus mitis SK321	66.059	99.442	0.657
comA	Streptococcus gordonii str. Challis substr. CH1	65.46	100	0.656
comA	Streptococcus pneumoniae TIGR4	65.778	99.442	0.654