Detailed information NTG1170054

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ACLV7Q_RS08090
• Genome accession: NZ_OZ217341
• Coordinates: 1673638..1675791 (+)
• Length: 717 a.a.
• NCBI ID: WP_411866005.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis C22
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1668638..1680791

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7Q_RS08055 (SMIC22_15830)	ccrZ	1668953..1669747 (-)	795	WP_000362999.1	cell cycle regulator CcrZ	-
ACLV7Q_RS08060	-	1669910..1670065 (-)	156	Protein_1541	type II CAAX prenyl endopeptidase Rce1 family protein	-
ACLV7Q_RS08065 (SMIC22_15860)	-	1670763..1670972 (-)	210	WP_033684778.1	Blp family class II bacteriocin	-
ACLV7Q_RS08070 (SMIC22_15870)	-	1670988..1671236 (-)	249	WP_218757006.1	Blp family class II bacteriocin	-
ACLV7Q_RS08075 (SMIC22_15880)	-	1671494..1672531 (-)	1038	WP_218757007.1	thioredoxin domain-containing protein	-
ACLV7Q_RS08080 (SMIC22_15890)	-	1672697..1673101 (-)	405	WP_218757008.1	immunity protein	-
ACLV7Q_RS08085 (SMIC22_15900)	-	1673121..1673357 (-)	237	WP_033684811.1	Blp family class II bacteriocin	-
ACLV7Q_RS08090 (SMIC22_15910)	comA/nlmT	1673638..1675791 (+)	2154	WP_411866005.1	peptide cleavage/export ABC transporter BlpA	Regulator
ACLV7Q_RS08095 (SMIC22_15920)	-	1675802..1677163 (+)	1362	WP_411866006.1	bacteriocin secretion accessory protein	-
ACLV7Q_RS08100 (SMIC22_15930)	blpC	1677220..1677375 (+)	156	WP_218757135.1	quorum-sensing system pheromone BlpC	-
ACLV7Q_RS08105 (SMIC22_15940)	-	1677417..1678757 (-)	1341	WP_218757136.1	sensor histidine kinase	-
ACLV7Q_RS08110 (SMIC22_15950)	comE/blpR	1678771..1679508 (-)	738	WP_218757137.1	response regulator transcription factor	Regulator
ACLV7Q_RS08115 (SMIC22_15960)	-	1679513..1679851 (-)	339	WP_218757138.1	LytTR family DNA-binding domain-containing protein	-
ACLV7Q_RS08120 (SMIC22_15970)	-	1680210..1680461 (+)	252	WP_001130045.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80792.85 Da
• Isoelectric Point: 7.9869

>NTDB_id=1170054 ACLV7Q_RS08090 WP_411866005.1 1673638..1675791(+) (comA/nlmT) [Streptococcus mitis isolate S. mitis C22]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLVIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLNFLPL
IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMGFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMF
IIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKL
VLNILILWFGAQLVMSSKISIGQLITFNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFKVQENPVHSHFL
MGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHI
NYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 2154 bp

>NTDB_id=1170054 ACLV7Q_RS08090 WP_411866005.1 1673638..1675791(+) (comA/nlmT) [Streptococcus mitis isolate S. mitis C22]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCTAGAGACTGCGGTGTTGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGAACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTATTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGGTTATTGGTGATCCTGACCCTTCTGTAAAAATCACCAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAACTTCCTTCCTCTG
ATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACGATTATCAATATCGGTGGTTCTTA
TTATCTCCAAGGAATCTTGGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTA
TTACCTATATCCTCCAACAAGTCATGGGCTTCTCCAGAGATTATCTCCTAACTGTTCTGAGTCAGAGATTAAGTATTGAT
GTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCTATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTC
ACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCCATTCTGA
TTCTTGTAGGGGGCGTCTTACTAGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCTATTCCTATATACATGTTC
ATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCAT
TATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAAT
TTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTA
GTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTT
TAACACACTTCTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCG
CTAATAACCGCTTGAACGAGGTCTATCTAGTCGAATCTGAATTTAAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTG
ATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGAT
TAAACAAGGAGATAAGGTTAGTCTAGTTGGAGTCAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCT
TTGAACCCTACAAAGGACATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATT
AATTACCTACCTCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACTTTGGGAGGTAATCATATGATTAG
CCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTC
AGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAATCTCCT
GTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTCAC
TGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGA
AAATCATTGAAGTTGGTAGTCATCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-649)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.028	99.721	0.718
comA	Streptococcus mitis NCTC 12261	66.339	99.442	0.66
comA	Streptococcus pneumoniae Rx1	65.778	99.442	0.654
comA	Streptococcus pneumoniae R6	65.778	99.442	0.654
comA	Streptococcus pneumoniae D39	65.778	99.442	0.654
comA	Streptococcus mitis SK321	65.778	99.442	0.654
comA	Streptococcus gordonii str. Challis substr. CH1	65.181	100	0.653
comA	Streptococcus pneumoniae TIGR4	65.498	99.442	0.651