Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ACLV7Q_RS08110 Genome accession   NZ_OZ217341
Coordinates   1678771..1679508 (-) Length   245 a.a.
NCBI ID   WP_218757137.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis C22     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1673771..1684508
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Q_RS08095 (SMIC22_15920) - 1675802..1677163 (+) 1362 WP_411866006.1 bacteriocin secretion accessory protein -
  ACLV7Q_RS08100 (SMIC22_15930) blpC 1677220..1677375 (+) 156 WP_218757135.1 quorum-sensing system pheromone BlpC -
  ACLV7Q_RS08105 (SMIC22_15940) - 1677417..1678757 (-) 1341 WP_218757136.1 sensor histidine kinase -
  ACLV7Q_RS08110 (SMIC22_15950) comE/blpR 1678771..1679508 (-) 738 WP_218757137.1 response regulator transcription factor Regulator
  ACLV7Q_RS08115 (SMIC22_15960) - 1679513..1679851 (-) 339 WP_218757138.1 LytTR family DNA-binding domain-containing protein -
  ACLV7Q_RS08120 (SMIC22_15970) - 1680210..1680461 (+) 252 WP_001130045.1 hypothetical protein -
  ACLV7Q_RS08125 (SMIC22_15980) - 1680490..1680813 (+) 324 WP_218757139.1 helicase BlpT -
  ACLV7Q_RS08130 (SMIC22_15990) pptB 1680875..1681924 (-) 1050 WP_218757140.1 ABC transporter permease Regulator
  ACLV7Q_RS08135 (SMIC22_16000) pptA 1681921..1682652 (-) 732 WP_023940790.1 ABC transporter ATP-binding protein Regulator
  ACLV7Q_RS08140 (SMIC22_16010) - 1682720..1683130 (+) 411 WP_218757141.1 HIT family protein -
  ACLV7Q_RS08145 (SMIC22_16020) - 1683140..1683427 (+) 288 WP_049487998.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28720.92 Da        Isoelectric Point: 6.4145

>NTDB_id=1170055 ACLV7Q_RS08110 WP_218757137.1 1678771..1679508(-) (comE/blpR) [Streptococcus mitis isolate S. mitis C22]
MRIFVLEDDFSQQARIETTIEKLLKDHHITPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEILKQEPRLLQCHRSFLINPANVIHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INKLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1170055 ACLV7Q_RS08110 WP_218757137.1 1678771..1679508(-) (comE/blpR) [Streptococcus mitis isolate S. mitis C22]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAAGCTAGAATTGAAACGACGATTGAGAAACTCTTGAAGGACCA
TCATATCACTCCCAGCTCTTTTGAGGTCTTTGGCAAACCAGACCAACTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGACATTGAGATTAGAAATGAGGAGATGAAGGGTCTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCTTATGCCCTCATCGTCTTTGTGACGACTCACTCAGAGTTTATGCCCCTGTCTTTTCGCTACCAAGTGTCTGCTTTGGA
CTACATTGATAAGGCCTTGTCAGCAGAGGAGTTTGAATCTCGGATCGAGACAGCCCTCCTCTATGCCAATGGTCAAGACA
GTAAAAGTCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTCCAGTATCCTTTTAAAGAGGTTTATTAT
CTTGAAACATCGCCCAGAGCCCATCGTGTTATTCTCTATACCAAGACAGACAGACTGGAATTTACAGCGAGTTTAGAGGA
GATTCTCAAGCAGGAGCCTCGTCTCCTGCAGTGTCATCGCTCTTTTCTCATCAATCCAGCCAATGTGATACATTTGGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCCCGTTATAAGGTCAGGGAAGTGTCTGAGGCC
ATCAATAAATTACACTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-241)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.846

100

0.543
  comE/comE1 Streptococcus equinus JB1

43.038

96.735

0.416
  comE/comE2 Streptococcus equinus JB1

37.19

98.776

0.367

Multiple sequence alignment