Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   ACLV7Q_RS00355 Genome accession   NZ_OZ217341
Coordinates   60201..61550 (+) Length   449 a.a.
NCBI ID   WP_218757516.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis C22     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 55201..66550
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Q_RS00320 (SMIC22_00590) - 56341..56529 (+) 189 WP_218757513.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  ACLV7Q_RS00325 (SMIC22_00600) - 56550..56717 (+) 168 WP_060805139.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  ACLV7Q_RS00330 (SMIC22_00610) - 56727..56897 (+) 171 WP_218757514.1 hypothetical protein -
  ACLV7Q_RS00335 (SMIC22_00620) - 56947..57135 (+) 189 WP_218757513.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  ACLV7Q_RS00340 (SMIC22_00630) - 57156..57323 (+) 168 WP_060805139.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  ACLV7Q_RS00345 (SMIC22_00640) - 57688..57876 (+) 189 WP_033680983.1 hypothetical protein -
  ACLV7Q_RS00350 (SMIC22_00650) comA 58035..60188 (+) 2154 WP_218757515.1 peptide cleavage/export ABC transporter ComA Regulator
  ACLV7Q_RS00355 (SMIC22_00660) comB 60201..61550 (+) 1350 WP_218757516.1 competence pheromone export protein ComB Regulator
  ACLV7Q_RS00360 (SMIC22_00670) purC 61826..62533 (+) 708 WP_000043295.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  ACLV7Q_RS00365 - 62535..62678 (+) 144 WP_078353133.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  ACLV7Q_RS00370 (SMIC22_00680) - 62733..66458 (+) 3726 WP_218757517.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49859.81 Da        Isoelectric Point: 5.5773

>NTDB_id=1170001 ACLV7Q_RS00355 WP_218757516.1 60201..61550(+) (comB) [Streptococcus mitis isolate S. mitis C22]
MKPEFLESAEFYNRRYHNFSSRVIVPMSLLLVFLLGFATFAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGELLVQYQEGAEGVQAEAYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYLSQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLASQNLAYSLYQSYKSQGEENPQAKAQAVAQVEAQLS
QLESSLATYRIQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLDQKILEAESGKKVQGNLLEKGKITASEDGVLH
LNPETSDSTMVAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARIKVGDSVRYTTTHDAKNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1170001 ACLV7Q_RS00355 WP_218757516.1 60201..61550(+) (comB) [Streptococcus mitis isolate S. mitis C22]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTGTCCCCAT
GTCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACATTTGCAGAGAAGGAGATGAGTTTATCAACTAGAGCTACTGTCG
AGCCTAGTCGAATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATCTGGAAGAAAATAAGCTG
GTTAAAAAGGGGGAGCTTCTGGTTCAATATCAGGAAGGGGCAGAGGGTGTCCAAGCAGAGGCCTATGCTAGTCAGTTGGA
CATGCTTAAGGATCAAAAAAAGCAATTGGAGTATTTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAATTTGGCTACCAAGCCACCTTTCGCGACTACCTCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGTCAAACCCAAGCTGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCTTACTCGCTCT
ATCAGTCCTATAAGTCTCAGGGTGAGGAAAATCCGCAAGCTAAGGCTCAGGCTGTTGCGCAGGTTGAAGCGCAGCTCTCT
CAGTTAGAATCCAGTCTTGCTACTTACCGTATTCAGTATGCAGGTTCAGGTACCCAGCAAGCTTATGCGTCAGGTTTAAG
CAGTCAATTGGAATCTCTTAAATCACAACACTTGGCTAAGGTTGGTCAGGAATTGACCCTTCTAGACCAGAAAATTTTGG
AGGCAGAATCGGGTAAGAAGGTTCAGGGAAATCTTTTAGAAAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTACCATGGTAGCAGAGGGGACTCTACTAGCCCAACTCTATCCGTCCTTGGAAAAAGA
AGGGAAAACCAAACTAACAGCTTATCTCAGTTCAAAGGATGTAGCAAGGATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCAAGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTCGGTACGGGGTGGAAGGTCG
TCTGCAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTAGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

97.327

100

0.973
  comB Streptococcus mitis NCTC 12261

95.991

100

0.96
  comB Streptococcus pneumoniae D39

95.768

100

0.958
  comB Streptococcus pneumoniae R6

95.768

100

0.958
  comB Streptococcus pneumoniae Rx1

95.768

100

0.958
  comB Streptococcus pneumoniae TIGR4

95.546

100

0.955
  comB Streptococcus gordonii str. Challis substr. CH1

56

100

0.561

Multiple sequence alignment