Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   ACLV7H_RS07835 Genome accession   NZ_OZ217340
Coordinates   1517528..1519429 (-) Length   633 a.a.
NCBI ID   WP_411866842.1    Uniprot ID   -
Organism   Streptococcus oralis isolate S. oralis A22     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1512528..1524429
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7H_RS07815 (SORA22_15730) - 1513661..1514935 (-) 1275 WP_411866840.1 hydroxymethylglutaryl-CoA reductase, degradative -
  ACLV7H_RS07820 (SORA22_15740) - 1514935..1516107 (-) 1173 WP_411866841.1 hydroxymethylglutaryl-CoA synthase -
  ACLV7H_RS07825 (SORA22_15750) - 1516226..1516681 (-) 456 WP_045590460.1 threonine/serine exporter family protein -
  ACLV7H_RS07830 (SORA22_15760) - 1516683..1517441 (-) 759 WP_045590459.1 threonine/serine exporter family protein -
  ACLV7H_RS07835 (SORA22_15770) stkP 1517528..1519429 (-) 1902 WP_411866842.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ACLV7H_RS07840 (SORA22_15780) - 1519426..1520166 (-) 741 WP_411866843.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACLV7H_RS07845 (SORA22_15790) rsmB 1520182..1521495 (-) 1314 WP_411866844.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ACLV7H_RS07850 (SORA22_15800) fmt 1521488..1522423 (-) 936 WP_411866845.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 68908.06 Da        Isoelectric Point: 8.2222

>NTDB_id=1169973 ACLV7H_RS07835 WP_411866842.1 1517528..1519429(-) (stkP) [Streptococcus oralis isolate S. oralis A22]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHHPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLSDRYQSVSEMYVDLSTSLSYNRRNEPKLVFDDASKADTKTLPKVPQSTLTSIPKAPAQEERPQSK
KPTQPMAEPAPAPKSAKKRKFKARYMILLASILLVAASLIWILSRTPATIDIPDVAGQTVAEAKEALKKSKFEAGEEKSE
TSDTVAEGRVIRTDPEAGSGRKEGTKVNLIVSSGKQSFQLSNYVGRKYTDVVAELKEKKVPENLIKMEEEESSESEPGTV
LRQTPASGSTYDLSKATTITLIVAKKVTSVSMPNYIGSSLEFTNNNLTQIVGVKEANIEVVEVSTAPEGTAEGTVVSQTP
RAGELVDLASTRIKISIYKPKTPPSTSSSNPAQRGNQGSTSTPNQGNQQGNQQGNTPSSSSSNHEGSHESSRD

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=1169973 ACLV7H_RS07835 WP_411866842.1 1517528..1519429(-) (stkP) [Streptococcus oralis isolate S. oralis A22]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAGCAGATTGGTCGGGGAGGCATGGCAGATGTTTA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTGGCGGTCAAGGTCCTGAGGACCAACTACCAGACGGACCCTATTG
CTGTGGCACGTTTCCAGCGTGAAGCAAGAGCCATGGCGGATCTGGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGATGGTCAACAGTACCTAGCTATGGAGTACGTAGCAGGGCTTGACCTTAAGCGTTATATCAAAGAACACCATCC
TCTTTCAAATGAAGAAGCAGTTCGAATCATGGGACAAATCCTCTTGGCCATGCGCTTAGCCCATACTAGAGGCATCGTTC
ACCGCGATTTGAAACCACAAAATATCCTACTAACCCCTGATGGCACAGCCAAGGTCACTGACTTTGGGATTGCGGTAGCC
TTTGCGGAGACCAGTCTGACTCAGACAAACTCGATGCTGGGCTCTGTTCATTATTTGTCACCTGAACAAGCGCGTGGTTC
TAAAGCGACCTTCCAGAGTGATATCTATGCAATGGGGATTATCTTCTATGAAATGCTGACGGGACATATCCCTTATGATG
GGGATAGCGCGGTGACCATTGCCCTCCAGCATTTCCAGAAGCCACTTCCGTCCGTCATAGCTGAAAACCCATCTGTCCCT
CAGGCTTTAGAAAATGTTGTCATCAAGGCAACTGCTAAGAAGCTGTCAGATCGTTATCAGTCTGTTTCGGAAATGTATGT
GGACTTGTCAACTAGCTTGTCTTATAATCGTCGGAATGAACCGAAACTGGTCTTTGACGATGCGAGTAAGGCAGACACTA
AGACTTTGCCTAAAGTTCCACAAAGTACACTGACGTCCATTCCTAAAGCTCCGGCGCAAGAAGAACGCCCTCAGTCAAAG
AAACCAACTCAACCGATGGCAGAGCCGGCTCCAGCGCCAAAATCAGCCAAGAAACGGAAGTTTAAGGCTCGCTATATGAT
TCTTTTGGCTAGTATTCTATTGGTTGCAGCCTCTTTGATTTGGATTTTGTCAAGAACACCAGCAACGATTGATATTCCTG
ACGTAGCTGGACAAACCGTTGCAGAGGCTAAGGAAGCTCTTAAAAAATCCAAGTTTGAAGCCGGTGAAGAAAAGTCAGAG
ACCAGCGATACAGTAGCAGAGGGACGTGTTATTCGAACGGATCCAGAAGCTGGTAGCGGCCGAAAAGAAGGAACCAAGGT
CAATTTGATTGTTTCTTCTGGGAAGCAATCTTTCCAATTGAGTAATTACGTCGGACGCAAGTATACGGATGTTGTAGCCG
AACTCAAGGAGAAGAAGGTTCCTGAAAATCTAATCAAGATGGAAGAGGAAGAATCCAGCGAAAGCGAACCTGGAACCGTC
CTTAGACAGACTCCTGCTTCGGGTTCGACTTATGATCTCTCAAAAGCTACTACGATTACCTTAATAGTAGCTAAGAAGGT
GACTAGTGTCAGCATGCCGAACTACATTGGTTCAAGCCTCGAGTTTACAAACAATAACTTGACTCAGATTGTCGGTGTGA
AGGAAGCAAATATTGAGGTTGTTGAAGTATCGACTGCTCCTGAAGGAACGGCAGAAGGAACTGTTGTAAGTCAAACGCCA
AGAGCAGGAGAACTGGTTGATCTTGCAAGTACGCGTATCAAGATTTCGATTTACAAACCGAAAACACCGCCGTCAACTTC
ATCCTCTAACCCTGCTCAACGAGGGAACCAGGGTTCTACATCAACACCAAATCAAGGGAACCAGCAAGGAAATCAACAAG
GGAACACTCCTTCTAGCAGTTCATCCAATCATGAAGGATCTCACGAAAGTTCTCGAGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(371-432)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

78.559

92.101

0.724
  stkP Streptococcus pneumoniae D39

78.216

92.101

0.72
  stkP Streptococcus pneumoniae R6

78.216

92.101

0.72
  stkP Streptococcus pneumoniae Rx1

78.045

92.101

0.719
  pknB Streptococcus mutans UA159

56.326

91.153

0.513
  stkP/pknB Streptococcus salivarius strain HSISS4

53.242

92.575

0.493

Multiple sequence alignment