Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   ACLV7H_RS05525 Genome accession   NZ_OZ217340
Coordinates   1058614..1059321 (-) Length   235 a.a.
NCBI ID   WP_045591274.1    Uniprot ID   A0A0F2D710
Organism   Streptococcus oralis isolate S. oralis A22     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1053614..1064321
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7H_RS05505 (SORA22_11060) - 1055216..1055563 (+) 348 WP_411866591.1 thioredoxin -
  ACLV7H_RS05510 (SORA22_11070) - 1055596..1056375 (-) 780 WP_411866592.1 potassium channel family protein -
  ACLV7H_RS05515 (SORA22_11080) vicX 1056461..1057270 (-) 810 WP_001289486.1 MBL fold metallo-hydrolase Regulator
  ACLV7H_RS05520 (SORA22_11090) micB 1057272..1058621 (-) 1350 WP_045591275.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACLV7H_RS05525 (SORA22_11100) micA 1058614..1059321 (-) 708 WP_045591274.1 response regulator YycF Regulator
  ACLV7H_RS05530 (SORA22_11110) mutY 1059397..1060557 (-) 1161 WP_045591272.1 A/G-specific adenine glycosylase -
  ACLV7H_RS05535 (SORA22_11120) pta 1060640..1061614 (-) 975 WP_411866593.1 phosphate acetyltransferase -
  ACLV7H_RS05540 (SORA22_11130) - 1061658..1062554 (-) 897 WP_411866594.1 RluA family pseudouridine synthase -
  ACLV7H_RS05545 (SORA22_11140) - 1062551..1063369 (-) 819 WP_045591267.1 NAD kinase -
  ACLV7H_RS05550 (SORA22_11150) - 1063353..1064024 (-) 672 WP_411866595.1 GTP pyrophosphokinase family protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26990.84 Da        Isoelectric Point: 4.6707

>NTDB_id=1169963 ACLV7H_RS05525 WP_045591274.1 1058614..1059321(-) (micA) [Streptococcus oralis isolate S. oralis A22]
MKKILIVDDEKPISDIIKFNMAKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTNLVSVDSQESDEKKSQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=1169963 ACLV7H_RS05525 WP_045591274.1 1058614..1059321(-) (micA) [Streptococcus oralis isolate S. oralis A22]
ATGAAAAAAATATTAATTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTTAATATGGCCAAGGAAGGTTATGA
AGTTGTTACAGCCTTCAATGGTCGTGAGGCAATCGAGCTATTTGAAGCAGAGCAACCAGATATTATTATCCTCGACTTGA
TGCTACCTGAAATTGATGGTTTAGAAGTTGCTAAAGCTATTCGTAAGACTAGTAGCGTTCCGATTATCATGCTATCAGCT
AAGGATAGCGAGTTTGACAAGGTTATTGGTTTAGAATTAGGTGCAGATGATTATGTTACAAAACCTTTCTCAAACCGTGA
GTTGCAAGCACGTGTTAAAGCCCTGCTTCGTCGTACCAACCTAGTTTCAGTTGATAGTCAAGAGTCTGACGAGAAGAAAT
CCCAGCCACTTCAGATTGGTGATTTGGAAATTGTCCCAGATGCTTACGTGGCAAAGAAATATGGTGAGGAATTAGATTTA
ACCCACCGTGAGTTTGAACTCTTGTATCACTTGGCATCTCATATTGGTCAAGTGATTACGCGTGAACACTTGCTTGAGAC
TGTATGGGGTTATGACTATTTTGGTGATGTTCGTACAGTGGACGTGACCATTAGACGCTTGCGTGAGAAAATAGAAGACA
CTCCAAGTCGTCCAGAGTACATTCTCACACGTCGTGGTGTTGGATACTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F2D710

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

92.308

99.574

0.919
  vicR Streptococcus mutans UA159

77.447

100

0.774
  covR Streptococcus salivarius strain HSISS4

43.59

99.574

0.434
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.29

98.298

0.426
  scnR Streptococcus mutans UA159

37.179

99.574

0.37

Multiple sequence alignment