Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   ACLV7H_RS05520 Genome accession   NZ_OZ217340
Coordinates   1057272..1058621 (-) Length   449 a.a.
NCBI ID   WP_045591275.1    Uniprot ID   A0A0F2D2S1
Organism   Streptococcus oralis isolate S. oralis A22     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1052272..1063621
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7H_RS05500 (SORA22_11050) - 1053386..1055104 (+) 1719 WP_411866590.1 phospho-sugar mutase -
  ACLV7H_RS05505 (SORA22_11060) - 1055216..1055563 (+) 348 WP_411866591.1 thioredoxin -
  ACLV7H_RS05510 (SORA22_11070) - 1055596..1056375 (-) 780 WP_411866592.1 potassium channel family protein -
  ACLV7H_RS05515 (SORA22_11080) vicX 1056461..1057270 (-) 810 WP_001289486.1 MBL fold metallo-hydrolase Regulator
  ACLV7H_RS05520 (SORA22_11090) micB 1057272..1058621 (-) 1350 WP_045591275.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ACLV7H_RS05525 (SORA22_11100) micA 1058614..1059321 (-) 708 WP_045591274.1 response regulator YycF Regulator
  ACLV7H_RS05530 (SORA22_11110) mutY 1059397..1060557 (-) 1161 WP_045591272.1 A/G-specific adenine glycosylase -
  ACLV7H_RS05535 (SORA22_11120) pta 1060640..1061614 (-) 975 WP_411866593.1 phosphate acetyltransferase -
  ACLV7H_RS05540 (SORA22_11130) - 1061658..1062554 (-) 897 WP_411866594.1 RluA family pseudouridine synthase -
  ACLV7H_RS05545 (SORA22_11140) - 1062551..1063369 (-) 819 WP_045591267.1 NAD kinase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51549.87 Da        Isoelectric Point: 4.5770

>NTDB_id=1169962 ACLV7H_RS05520 WP_045591275.1 1057272..1058621(-) (micB) [Streptococcus oralis isolate S. oralis A22]
MIEDIRQTILTSDFIFILILLGFILVVTLLLLENRRDNIRLKEINQKVKDLIAGDYSQVLDLQGSTEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILSYMTDGVLATNRRGQITMINDMAKKQLGVQKEDVLNKSILELLKIEDEYELRDLITQIPE
LTIDSQDVNGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSQLDVELINFTAFITFILNRFDKMRSQDDEKKYELVRDYPINSVW
IEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDDQMVLSIKDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEIWEDEIED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1169962 ACLV7H_RS05520 WP_045591275.1 1057272..1058621(-) (micB) [Streptococcus oralis isolate S. oralis A22]
ATGATTGAAGATATTAGACAAACTATTCTGACCAGCGATTTTATCTTTATCTTGATTTTACTTGGTTTTATCCTGGTGGT
GACCTTGCTCTTACTGGAAAATCGTCGGGATAATATCCGTCTGAAGGAGATAAATCAAAAGGTTAAGGACTTGATTGCAG
GTGATTATTCTCAAGTTTTGGACTTGCAAGGAAGTACAGAAATCACCAATATCACCAATAATCTGAACGATTTATCAGAA
GTAATTCGTTTGACCCAAGAAAATCTGGAACAAGAGAGTAAACGATTGAACAGTATTCTTTCTTACATGACAGATGGCGT
TCTTGCGACCAATCGCCGTGGCCAGATTACTATGATCAACGATATGGCCAAGAAACAGCTCGGTGTGCAGAAAGAAGATG
TTCTGAATAAAAGCATCCTCGAATTACTCAAGATAGAAGATGAGTATGAGCTACGTGATCTGATTACACAGATTCCTGAG
TTGACGATTGACTCCCAGGATGTAAATGGTGAATACCTAAGCCTTCGTGTACGTTTTGCTCTGGTTCGTCGTGAGTCAGG
TTTCATCTCTGGTTTGGTTGCCGTTTTACATGATACGACCGAGCAGGAGAAGGAAGAGCGTGAGCGAAGACTCTTTGTTT
CGAACGTGAGTCATGAGTTGCGGACTCCTTTGACCAGTGTCAAGTCTTATCTCGAAGCCTTGGACGAGGGAGCATTGTAT
GATCCTGTTGCTCCTGATTTTATCAAGGTTTCGCTTGATGAAACCAACCGTATGATGCGGATGGTGACAGATCTCTTACA
TCTCTCTCGTATTGATAATGCGACAAGTCAGCTAGATGTGGAATTGATTAATTTTACAGCCTTTATCACCTTTATTCTCA
ACCGCTTTGATAAGATGAGAAGCCAGGATGACGAGAAAAAATATGAACTTGTTAGAGATTACCCAATCAATTCAGTTTGG
ATCGAGATTGATACCGATAAAATGACTCAGGTGGTTGATAATATTCTCAATAATGCCATCAAGTACTCACCAGATGGTGG
CAAAATTACTGTCAGCATGAAGACCACTGATGACCAGATGGTTTTATCCATCAAAGACCAAGGTTTAGGTATTCCAAAGC
AAGATTTGCCTAAGATTTTTGACCGTTTCTACCGTGTGGATCGTGCAAGAAGCCGGGCTCAAGGTGGAACTGGTCTAGGT
CTAGCCATCGCAAAAGAAATCATTAAACAACACAATGGCTTTATTTGGGCCAAAAGTGAATATGGTAAGGGTTCAACCTT
TACCATCGTGCTCCCTTATGATAAGGATGCCGTAAAAGAAGAAATATGGGAGGACGAAATAGAAGACTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F2D2S1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

89.522

97.773

0.875
  vicK Streptococcus mutans UA159

70.398

89.532

0.63

Multiple sequence alignment