Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   AB3222_RS07740 Genome accession   NZ_OZ064360
Coordinates   1524873..1526012 (-) Length   379 a.a.
NCBI ID   WP_150280855.1    Uniprot ID   -
Organism   Leuconostoc carnosum isolate Leuconostoc carnosum A1b-VegA     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1519873..1531012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3222_RS07715 mutY 1519961..1520983 (-) 1023 WP_014974928.1 A/G-specific adenine glycosylase -
  AB3222_RS07720 - 1521107..1521250 (+) 144 WP_014974929.1 hypothetical protein -
  AB3222_RS07725 - 1521390..1522787 (+) 1398 WP_014974930.1 DHA2 family efflux MFS transporter permease subunit -
  AB3222_RS07730 thiD 1522853..1523662 (-) 810 WP_150280854.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  AB3222_RS07735 rlmH 1523740..1524219 (-) 480 WP_014974932.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  AB3222_RS07740 htrA 1524873..1526012 (-) 1140 WP_150280855.1 S1C family serine protease Regulator
  AB3222_RS07745 yycI 1526076..1526861 (-) 786 WP_150280856.1 two-component system regulatory protein YycI -
  AB3222_RS07750 yycH 1526892..1528196 (-) 1305 WP_150280857.1 two-component system activity regulator YycH -
  AB3222_RS07755 walK 1528186..1530057 (-) 1872 WP_014974936.1 cell wall metabolism sensor histidine kinase WalK -
  AB3222_RS07760 yycF 1530189..1530896 (-) 708 WP_014974937.1 response regulator YycF -

Sequence

Protein


Download         Length: 379 a.a.        Molecular weight: 39575.01 Da        Isoelectric Point: 9.6237

>NTDB_id=1166492 AB3222_RS07740 WP_150280855.1 1524873..1526012(-) (htrA) [Leuconostoc carnosum isolate Leuconostoc carnosum A1b-VegA]
MKQYSLTKIVLTGIIAGVIGGGALLYGQRGVENLQTSTQKVNTKASETSTIPKNATATTAYDKISDAVVSVLNFSQTGQR
RYEESSEGSGVIYKKAGDSAYIVTNNHVISGASKIQVMMHDGKKVEASLVGKDIMTDLAVLKMDAKNVTATASFGDSNKI
QVGQKVLAIGSPLGSQYASSVTQGIISAKKRLVEASSENGQSYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
SSSSGTSVEGMGFAIPSDQVVNIVNELVKNGKITRPAIGISLVELSEITVDDQKALLKIPETVTGGVVVMGTTDNGPAAK
AGLKKYDVITAIEGKTVAGQADLREELYKHKLGDTISVTYYHQATKHTVNIKLTQKLGS

Nucleotide


Download         Length: 1140 bp        

>NTDB_id=1166492 AB3222_RS07740 WP_150280855.1 1524873..1526012(-) (htrA) [Leuconostoc carnosum isolate Leuconostoc carnosum A1b-VegA]
ATGAAACAATATTCATTAACAAAAATCGTATTAACTGGTATCATCGCCGGTGTTATCGGTGGTGGCGCATTATTATATGG
GCAACGCGGTGTTGAAAATTTGCAAACATCGACACAAAAGGTTAACACAAAGGCTAGTGAAACTAGTACTATCCCCAAAA
ACGCTACAGCCACAACGGCTTATGATAAAATCTCTGATGCTGTTGTTTCAGTATTAAATTTTTCACAAACTGGTCAGAGA
CGCTATGAAGAGTCATCTGAAGGTTCTGGTGTGATTTACAAGAAAGCCGGCGATTCAGCCTATATCGTGACCAATAATCA
CGTGATTAGCGGTGCCTCTAAGATTCAAGTAATGATGCATGATGGTAAAAAGGTTGAAGCATCATTAGTCGGCAAAGATA
TCATGACTGATTTAGCTGTTTTAAAAATGGATGCCAAAAATGTGACGGCAACGGCATCATTTGGTGATTCAAATAAAATC
CAAGTTGGTCAAAAGGTGTTAGCTATCGGTTCTCCCCTGGGTTCACAGTACGCCTCTTCAGTGACTCAAGGTATCATTTC
TGCCAAAAAACGTTTAGTTGAGGCGAGCTCTGAAAACGGGCAAAGTTATGGTGGATCAACAGTTATTCAAACAGATGCTG
CCATTAATCCTGGTAACTCAGGTGGACCACTGATTAATTTTGCAGGTCAAGTCATTGGTATTAACTCAATGAAGTTATCC
TCCTCCTCATCTGGTACGAGCGTTGAAGGGATGGGATTTGCAATACCTTCAGATCAGGTGGTTAACATTGTCAATGAACT
GGTGAAGAATGGTAAAATCACAAGGCCGGCTATTGGTATTAGCTTAGTCGAACTTTCCGAAATAACGGTTGATGACCAAA
AAGCTTTACTGAAAATTCCAGAAACTGTAACAGGTGGTGTCGTGGTCATGGGCACGACGGATAATGGGCCGGCAGCTAAA
GCTGGTTTGAAGAAGTACGACGTGATTACTGCTATTGAAGGTAAAACAGTGGCTGGTCAAGCAGACTTGCGTGAGGAGCT
CTACAAGCATAAATTAGGAGACACAATCAGCGTAACCTACTATCACCAAGCAACCAAGCACACAGTCAATATTAAATTAA
CACAGAAATTAGGAAGCTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(276-373)

Peptidase family M50 (Peptidase_M50)

(41-375)

Trypsin-like peptidase domain (Trypsin_2)

(88-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

47.044

100

0.483
  htrA Streptococcus mutans UA159

52.059

89.71

0.467
  htrA Streptococcus gordonii str. Challis substr. CH1

46.438

100

0.464
  htrA Streptococcus pneumoniae TIGR4

50.729

90.501

0.459
  htrA Streptococcus pneumoniae D39

50.729

90.501

0.459
  htrA Streptococcus pneumoniae Rx1

50.729

90.501

0.459
  htrA Streptococcus pneumoniae R6

50.729

90.501

0.459

Multiple sequence alignment