Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   U8955_RS00485 Genome accession   NZ_OY769914
Coordinates   72585..73934 (+) Length   449 a.a.
NCBI ID   WP_038804296.1    Uniprot ID   -
Organism   Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 67585..78934
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U8955_RS00445 (SDENT7746_00445) - 67611..67847 (+) 237 WP_000136453.1 acyl carrier protein -
  U8955_RS00450 (SDENT7746_00450) - 68293..68436 (+) 144 WP_038804302.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  U8955_RS00455 (SDENT7746_00455) - 68452..68610 (+) 159 WP_038804301.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  U8955_RS00460 (SDENT7746_00465) - 68994..69149 (+) 156 WP_000732133.1 hypothetical protein -
  U8955_RS00465 (SDENT7746_00470) - 69188..69400 (+) 213 WP_038804300.1 hypothetical protein -
  U8955_RS00470 (SDENT7746_00475) - 69481..69660 (+) 180 WP_038804299.1 hypothetical protein -
  U8955_RS00475 (SDENT7746_00480) - 70059..70253 (+) 195 WP_038804298.1 hypothetical protein -
  U8955_RS00480 (SDENT7746_00485) comA 70419..72572 (+) 2154 WP_038804297.1 peptide cleavage/export ABC transporter ComA Regulator
  U8955_RS00485 (SDENT7746_00490) comB 72585..73934 (+) 1350 WP_038804296.1 competence pheromone export protein ComB Regulator
  U8955_RS00490 (SDENT7746_00495) purC 74102..74809 (+) 708 WP_038804295.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  U8955_RS00495 (SDENT7746_00500) - 74866..78591 (+) 3726 WP_038804294.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50047.09 Da        Isoelectric Point: 5.6366

>NTDB_id=1161690 U8955_RS00485 WP_038804296.1 72585..73934(+) (comB) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MQPEFLESAEFYNRRYHNFSSRVILPMSLLLVFLLGFAVFAEKEISLSTRATVEPSRIIANIQSTSNQRIVANYLEENKL
VKQGDLLVQYQQGAEAVQAEAYANQLEMFKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQANSLRSNVSQQN
ASISSQNAAASQSQSEIGNLIRQTQDKIRDYKTAKSAIEKGDQLDSQNPAYSFYQTYKNQAGEDPQAKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAYASGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSDSTMVAEGTLLAQLYPALERERKTKLTAYLSSKDVARLKVGDSIRFTTNKDANKELVLVSAITNIDATATKTEK
GNFFKIEAETSLAPEQAEKLRYGSEGRLTLITGKKSYLRYYLDQFLNRE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1161690 U8955_RS00485 WP_038804296.1 72585..73934(+) (comB) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGCAACCAGAATTTTTAGAAAGTGCGGAGTTTTACAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCGCTCCTACTCGTGTTTTTACTGGGATTTGCAGTTTTTGCAGAGAAGGAGATTAGTTTATCTACCAGAGCAACTGTCG
AACCTAGTCGGATTATTGCCAACATCCAGTCGACTAGCAATCAACGCATCGTGGCCAATTATCTAGAAGAAAACAAACTA
GTCAAGCAGGGGGATCTCCTCGTTCAGTACCAGCAAGGGGCGGAAGCTGTTCAAGCTGAAGCATACGCCAATCAGTTGGA
GATGTTTAAGGATCAAAAAAAACAGTTAGGTTATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAGGCAG
ATAAGTTTGGTTATCAGGAGATGTTTCGAGACTATCTCAGCCAAGCGAATAGTCTGAGGAGTAATGTTTCTCAGCAAAAT
GCCAGCATCTCCTCACAGAATGCGGCAGCAAGTCAGAGTCAGTCCGAGATTGGCAATCTTATCAGACAAACACAGGATAA
AATTCGAGATTACAAAACAGCTAAGTCAGCGATTGAAAAGGGAGATCAACTGGATAGTCAGAATCCAGCCTACTCTTTTT
ACCAGACCTATAAAAACCAAGCTGGAGAAGATCCGCAAGCTAAATCGCAAGTTATTGCACAGGTGGATGCTCAAATTGCC
CAGCTAGAGTCTAGTTTAGCTACTTATCGTGTACAGTATGCGGGATCTGGAGCTCAACAAGCCTACGCAAGTGGACTGGA
TAGTCAGCTTGAATCCCTTAAGTCCCAGCACCTAGTCAAAGTCGGTCAGGAATTAACCCTTTTGGATCAGAAAATTTTAG
AAGCGGAGTCGGGTAAGAAAGTCCAAGGAGGTCTCCTAGATAAGGGGAAGATTACAGCAAGCGAGGATGGGGTACTTCAC
CTTAATCCTGAGACCAGTGATTCTACCATGGTTGCAGAAGGAACCCTGCTAGCCCAACTCTACCCGGCCTTGGAACGAGA
AAGAAAAACCAAACTCACAGCTTATCTCAGTTCAAAAGATGTTGCAAGACTTAAGGTAGGTGATTCTATCCGTTTTACTA
CAAACAAGGATGCCAACAAAGAGCTCGTTCTTGTTTCTGCGATTACGAATATTGATGCGACAGCTACCAAGACTGAAAAG
GGAAATTTCTTTAAAATAGAGGCAGAGACAAGTCTGGCTCCTGAACAGGCAGAAAAACTTCGCTACGGTTCAGAAGGACG
TTTGACACTAATCACAGGAAAGAAAAGTTATCTGCGATATTACTTAGATCAATTTTTGAACAGAGAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae R6

80.178

100

0.802
  comB Streptococcus pneumoniae Rx1

80.178

100

0.802
  comB Streptococcus pneumoniae D39

80.178

100

0.802
  comB Streptococcus mitis SK321

79.955

100

0.8
  comB Streptococcus pneumoniae TIGR4

79.733

100

0.797
  comB Streptococcus mitis NCTC 12261

78.396

100

0.784
  comB Streptococcus gordonii str. Challis substr. CH1

54.889

100

0.55

Multiple sequence alignment