Detailed information NTG1161689

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: U8955_RS00480
• Genome accession: NZ_OY769914
• Coordinates: 70419..72572 (+)
• Length: 717 a.a.
• NCBI ID: WP_038804297.1
• Uniprot ID: A0A7T3E0M2
• Organism: Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 65419..77572

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U8955_RS00435 (SDENT7746_00435)	recO	65847..66617 (+)	771	WP_038804304.1	DNA repair protein RecO	-
U8955_RS00440 (SDENT7746_00440)	plsX	66614..67606 (+)	993	WP_038804303.1	phosphate acyltransferase PlsX	-
U8955_RS00445 (SDENT7746_00445)	-	67611..67847 (+)	237	WP_000136453.1	acyl carrier protein	-
U8955_RS00450 (SDENT7746_00450)	-	68293..68436 (+)	144	WP_038804302.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
U8955_RS00455 (SDENT7746_00455)	-	68452..68610 (+)	159	WP_038804301.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
U8955_RS00460 (SDENT7746_00465)	-	68994..69149 (+)	156	WP_000732133.1	hypothetical protein	-
U8955_RS00465 (SDENT7746_00470)	-	69188..69400 (+)	213	WP_038804300.1	hypothetical protein	-
U8955_RS00470 (SDENT7746_00475)	-	69481..69660 (+)	180	WP_038804299.1	hypothetical protein	-
U8955_RS00475 (SDENT7746_00480)	-	70059..70253 (+)	195	WP_038804298.1	hypothetical protein	-
U8955_RS00480 (SDENT7746_00485)	comA	70419..72572 (+)	2154	WP_038804297.1	peptide cleavage/export ABC transporter ComA	Regulator
U8955_RS00485 (SDENT7746_00490)	comB	72585..73934 (+)	1350	WP_038804296.1	competence pheromone export protein ComB	Regulator
U8955_RS00490 (SDENT7746_00495)	purC	74102..74809 (+)	708	WP_038804295.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80350.62 Da
• Isoelectric Point: 6.9424

>NTDB_id=1161689 U8955_RS00480 WP_038804297.1 70419..72572(+) (comA) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MKFGKKHYRPQVDQMDCGVASLAMIFSYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEELGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVTGQDKKTIHIADPDPGVKLTKISRERFAQEWTGVSLFMAPSPDYKPHKEKKQGLLSFLPI
LFKQRGLITNIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTILIISLVLFSQNMTLFFISLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVAYLKKSFTYSRAESQQKALKKLAQL
LLNVAVLWMGAVLVMDGKMSLGQLITYSTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSMM
KGDMTLKQVHYKYGYGRDVLSDINLTIPQDSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGNHADLLARGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=1161689 U8955_RS00480 WP_038804297.1 70419..72572(+) (comA) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGAAATTTGGGAAAAAACACTATCGTCCTCAGGTGGATCAGATGGATTGCGGCGTGGCTTCCTTGGCTATGATATTTAG
CTACTACGGTAGTTATTACTCCTTGGCTCATCTACGAGAGTTGGCCAAGACGACCATGGATGGGACGACTGCTTTGGGGC
TTGTAAAGGTGGCAGAGGAGCTTGGCTTTGAGACGCGGGCTATCAAGGCGGATATGACGCTCTTTGATCTGCCTGATTTG
ACTTTTCCTTTTGTAGCCCATGTGCTCAAGGAAGGGAAATTGCTCCACTACTATGTGGTGACAGGTCAGGATAAGAAGAC
CATCCATATCGCTGATCCAGATCCTGGTGTCAAGCTGACCAAGATTTCCCGTGAGCGATTTGCGCAAGAGTGGACAGGGG
TCAGTCTCTTTATGGCGCCATCTCCAGACTATAAACCTCATAAGGAGAAAAAACAGGGGCTCCTATCCTTCTTGCCCATC
TTATTCAAACAGCGTGGCTTAATTACCAATATCGTACTAGCGACACTCTTGGTAACCCTGATTAACATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACCTATGTGCCAGATCAGATGCGTTCGACGCTGGGTATCATCTCTATTGGTTTGGTCA
TCGTCTATATCCTCCAGCAAATTTTGTCCTACGCGCAGGAGTATCTCTTACTTGTTTTGGGGCAACGTCTGTCAATTGAT
GTGATTTTATCCTACATCAAGCATGTTTTTCACCTGCCAATGTCCTTTTTTGCGACACGCAGGACAGGGGAAATCGTGTC
TCGTTTCACGGATGCTAACAGTATCATTGACGCGCTAGCGTCGACCATTTTATCTATCTTTTTGGATGTGTCGACGATTC
TGATTATTTCGCTTGTCTTGTTTTCACAAAATATGACACTCTTTTTCATTAGTCTACTTGCGCTTCCCATCTATACAGTG
ATTATCTTTGCCTTTATGAAGCCTTTTGAAAAGATGAATCGGGACACTATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATCGAGGACATCAATGGTATTGAGACCATTAAGTCTTTGACCAGTGAAAGTTCACGCTATCAAAAGATTGACAAGGAAT
TTGTAGCTTATCTGAAAAAATCCTTTACCTATAGTCGAGCAGAAAGTCAACAAAAGGCTCTTAAAAAGCTTGCTCAGCTT
CTGCTCAATGTTGCTGTTCTCTGGATGGGAGCTGTTCTTGTCATGGATGGCAAGATGAGCTTGGGTCAGCTGATTACCTA
TAGCACCCTGCTTGTTTACTTTACCAATCCTTTGGAAAATATCATCAACCTACAAACCAAACTTCAGACAGCGCAGGTTG
CCAATAATCGCTTAAATGAGGTTTATCTAGTGGCTTCGGAGTTTGAGGAGAAGAAAACGGTAGAAGATTTGAGTATGATG
AAGGGGGATATGACCCTTAAACAAGTTCACTATAAGTATGGCTATGGTCGTGATGTCTTGTCGGATATCAATTTGACGAT
CCCACAAGATTCTAAAGTGGCTTTCGTGGGAATTTCAGGATCAGGCAAGACAACTTTGGCCAAGATGATGGTTAATTTTT
ACGATCCAAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTTAATCAGATTGATAAAAAGGCCCTGCGCCAGTACATC
AACTATCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTCCTTGGAGCCAAGGAGGGGACGAC
TCAGGAAGATATCTTACGGGCTGTTGAATTGGCCGAGATTCGGGAGGATATCGAGAGGATGCCACTGAATTACCAGACAG
AATTAACTTCGGATGGGGCAGGGATTTCTGGTGGGCAACGGCAACGAATCGCTCTGGCGCGTGCTCTCTTGACAGATGCG
CCTGTCTTGATATTGGATGAGGCGACCAGCAGTCTGGATATCTTGACAGAGAAGCGGATTGTGGATAATCTCATGGCTTT
AGACAAGACCTTGATTTTCATCGCCCACCGCTTGACCATCGCTGAGCGGACAGAGAAGGTTGTTGTCTTGGATCAGGGTA
AGATTGTCGAAGAAGGCAATCATGCTGATTTGCTTGCTCGAGGTGGATTTTACGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterProScan.

• Peptidase C39 family (Peptidase_C39) (6-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-650)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	95.119	100	0.951
comA	Streptococcus pneumoniae Rx1	94.7	100	0.947
comA	Streptococcus pneumoniae D39	94.7	100	0.947
comA	Streptococcus pneumoniae R6	94.7	100	0.947
comA	Streptococcus mitis SK321	94.421	100	0.944
comA	Streptococcus pneumoniae TIGR4	94.282	100	0.943
comA	Streptococcus gordonii str. Challis substr. CH1	80.753	100	0.808
comA/nlmT	Streptococcus mutans UA159	64.296	100	0.643