Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   QOR49_RS01105 Genome accession   NZ_OX460938
Coordinates   187843..188886 (+) Length   347 a.a.
NCBI ID   WP_283572726.1    Uniprot ID   -
Organism   Streptococcus agalactiae isolate MRI Z2-318     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 182843..193886
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QOR49_RS01095 - 186440..186805 (+) 366 WP_000285373.1 DUF1033 family protein -
  QOR49_RS01100 comYA 186978..187949 (+) 972 WP_000250805.1 competence type IV pilus ATPase ComGA Machinery gene
  QOR49_RS01105 comYB 187843..188886 (+) 1044 WP_283572726.1 competence type IV pilus assembly protein ComGB Machinery gene
  QOR49_RS01110 comYD 188883..189311 (+) 429 WP_000793382.1 competence type IV pilus minor pilin ComGD Machinery gene
  QOR49_RS01115 comGE 189283..189582 (+) 300 WP_000234804.1 competence type IV pilus minor pilin ComGE -
  QOR49_RS01120 comGF 189536..189997 (+) 462 WP_001878820.1 competence type IV pilus minor pilin ComGF -
  QOR49_RS01125 comGG 189975..190346 (+) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG -
  QOR49_RS01130 comYH 190461..191435 (+) 975 WP_001008574.1 N-6 DNA methylase Machinery gene
  QOR49_RS01135 - 191467..192660 (+) 1194 WP_000047534.1 acetate kinase -
  QOR49_RS01140 - 192812..193018 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  QOR49_RS01145 - 193077..193214 (+) 138 WP_001865900.1 hypothetical protein -
  QOR49_RS01150 - 193255..193710 (+) 456 WP_000905673.1 hypothetical protein -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39935.66 Da        Isoelectric Point: 9.9643

>NTDB_id=1159016 QOR49_RS01105 WP_283572726.1 187843..188886(+) (comYB) [Streptococcus agalactiae isolate MRI Z2-318]
MDKWISWLKKDISVRNRHKSKKLSLKKQRKVVQLFNNLFASGFSLTDMVTFLKRSKLLSDCYTDSMNKALLEGKDLSKML
GELGFSDTVITQVALADLHGNISRSLLKIESYLANLLLVRKKVIEVATYPLILLSFLVLIMIGLRNYLMPQLGENNFATR
LITNVPNIFLLLLAVVLIFSLIFYIIQKRLSRIKVACFLTTIPLVGSYVKLYLTAYYAREWGNLLSQGIELNQIVKVMQN
QKSKLFREIGYDMEEGFLSGKAFHQKVLDYPFFLTELSLMIEYGQVKAKLGTELDIYADEKWEDFFTKLARATQLIQPVI
FIFVALIIVMIYAAMLLPMYQNMEILS

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=1159016 QOR49_RS01105 WP_283572726.1 187843..188886(+) (comYB) [Streptococcus agalactiae isolate MRI Z2-318]
ATAGACAAGTGGATATCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAA
ACAACGGAAAGTAGTCCAACTTTTTAATAATCTTTTTGCTAGTGGTTTTTCTTTAACTGATATGGTCACCTTCTTAAAGA
GGAGTAAGTTATTGTCTGATTGTTATACAGATAGTATGAATAAGGCATTATTAGAGGGAAAAGATTTATCAAAAATGTTA
GGAGAGTTAGGTTTTTCTGACACTGTTATCACACAGGTTGCATTAGCTGATTTGCATGGTAACATTTCAAGGAGCCTACT
AAAGATTGAGTCTTATTTAGCTAATCTTTTGTTAGTTAGAAAAAAAGTAATAGAAGTAGCTACTTACCCATTGATATTAT
TGTCTTTTCTGGTGCTAATTATGATTGGCCTTAGGAATTATTTAATGCCCCAATTAGGAGAAAATAATTTTGCAACTAGA
CTGATTACAAATGTGCCGAATATTTTCTTATTACTTTTAGCAGTTGTACTTATTTTTAGTTTAATATTTTATATTATTCA
AAAGCGATTGTCGCGCATTAAAGTAGCTTGTTTTTTAACAACAATTCCCTTAGTTGGATCATATGTTAAGCTTTATTTAA
CTGCTTACTATGCCCGTGAGTGGGGAAATTTATTAAGTCAAGGTATTGAATTGAACCAAATTGTTAAAGTAATGCAAAAT
CAGAAATCCAAACTTTTTAGGGAAATAGGATATGACATGGAAGAAGGTTTTCTATCAGGTAAAGCATTTCACCAAAAAGT
ATTAGACTATCCGTTTTTCTTAACTGAGCTTAGTTTAATGATTGAATATGGCCAAGTTAAGGCGAAATTAGGAACAGAGT
TAGATATATATGCTGATGAGAAGTGGGAGGATTTTTTTACAAAATTAGCTAGAGCGACCCAGTTAATCCAACCCGTTATT
TTTATTTTTGTAGCTCTTATCATTGTTATGATTTATGCAGCAATGCTGTTACCAATGTATCAAAATATGGAGATATTATC
ATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(34-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

62.17

98.271

0.611
  comYB Streptococcus mutans UA159

61.877

98.271

0.608
  comYB Streptococcus gordonii str. Challis substr. CH1

56.305

98.271

0.553
  comGB/cglB Streptococcus mitis NCTC 12261

55.224

96.542

0.533
  comGB/cglB Streptococcus mitis SK321

54.627

96.542

0.527
  comGB/cglB Streptococcus pneumoniae Rx1

53.731

96.542

0.519
  comGB/cglB Streptococcus pneumoniae D39

53.731

96.542

0.519
  comGB/cglB Streptococcus pneumoniae R6

53.731

96.542

0.519
  comGB/cglB Streptococcus pneumoniae TIGR4

53.731

96.542

0.519
  comGB Lactococcus lactis subsp. cremoris KW2

50.148

97.118

0.487

Multiple sequence alignment