Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | QOR49_RS01130 | Genome accession | NZ_OX460938 |
| Coordinates | 190461..191435 (+) | Length | 324 a.a. |
| NCBI ID | WP_001008574.1 | Uniprot ID | A0AAV3JGK6 |
| Organism | Streptococcus agalactiae isolate MRI Z2-318 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 190676..241234 | 190461..191435 | flank | -759 |
Gene organization within MGE regions
Location: 190461..241234
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QOR49_RS01130 | comYH | 190461..191435 (+) | 975 | WP_001008574.1 | N-6 DNA methylase | Machinery gene |
| QOR49_RS01135 | - | 191467..192660 (+) | 1194 | WP_000047534.1 | acetate kinase | - |
| QOR49_RS01140 | - | 192812..193018 (+) | 207 | WP_000798241.1 | helix-turn-helix transcriptional regulator | - |
| QOR49_RS01145 | - | 193077..193214 (+) | 138 | WP_001865900.1 | hypothetical protein | - |
| QOR49_RS01150 | - | 193255..193710 (+) | 456 | WP_000905673.1 | hypothetical protein | - |
| QOR49_RS01155 | - | 193779..194444 (+) | 666 | WP_000008113.1 | type II CAAX endopeptidase family protein | - |
| QOR49_RS01160 | proC | 194465..195235 (-) | 771 | WP_001865901.1 | pyrroline-5-carboxylate reductase | - |
| QOR49_RS01165 | pepA | 195305..196372 (-) | 1068 | WP_001281323.1 | glutamyl aminopeptidase | - |
| QOR49_RS01170 | - | 196557..196796 (-) | 240 | WP_000660180.1 | hypothetical protein | - |
| QOR49_RS01175 | - | 196957..197241 (+) | 285 | WP_000791272.1 | DUF4651 domain-containing protein | - |
| QOR49_RS01180 | - | 197238..197561 (+) | 324 | WP_000602781.1 | thioredoxin family protein | - |
| QOR49_RS01185 | ytpR | 197594..198220 (+) | 627 | WP_000578328.1 | YtpR family tRNA-binding protein | - |
| QOR49_RS01190 | - | 198274..198990 (-) | 717 | WP_000186185.1 | class I SAM-dependent methyltransferase | - |
| QOR49_RS01195 | ssbA | 199071..199466 (+) | 396 | WP_000282447.1 | single-stranded DNA-binding protein | Machinery gene |
| QOR49_RS01200 | - | 199590..200234 (+) | 645 | WP_000416612.1 | HAD family hydrolase | - |
| QOR49_RS01205 | - | 200261..202006 (+) | 1746 | WP_000930334.1 | LytS/YhcK type 5TM receptor domain-containing protein | - |
| QOR49_RS01210 | - | 201987..202727 (+) | 741 | WP_000697630.1 | LytTR family transcriptional regulator DNA-binding domain-containing protein | - |
| QOR49_RS01215 | - | 202897..203352 (+) | 456 | WP_000683316.1 | CidA/LrgA family protein | - |
| QOR49_RS01220 | lrgB | 203354..204082 (+) | 729 | WP_000421726.1 | antiholin-like protein LrgB | - |
| QOR49_RS01225 | - | 204325..205953 (+) | 1629 | WP_000170504.1 | ABC transporter substrate-binding protein | - |
| QOR49_RS01230 | - | 206066..207043 (+) | 978 | WP_000680645.1 | ABC transporter permease | - |
| QOR49_RS01235 | - | 207040..207861 (+) | 822 | WP_000603397.1 | ABC transporter permease | - |
| QOR49_RS01240 | - | 207873..208676 (+) | 804 | WP_000140984.1 | ABC transporter ATP-binding protein | - |
| QOR49_RS01245 | - | 208660..209286 (+) | 627 | WP_000171311.1 | ABC transporter ATP-binding protein | - |
| QOR49_RS01250 | treP | 209569..211599 (+) | 2031 | WP_000434616.1 | PTS system trehalose-specific EIIBC component | - |
| QOR49_RS01255 | treC | 211821..213446 (+) | 1626 | WP_000151017.1 | alpha,alpha-phosphotrehalase | - |
| QOR49_RS01260 | - | 213662..215698 (+) | 2037 | WP_000228180.1 | BglG family transcription antiterminator | - |
| QOR49_RS01265 | - | 215701..215985 (+) | 285 | WP_000944235.1 | PTS sugar transporter subunit IIB | - |
| QOR49_RS01270 | - | 215998..217353 (+) | 1356 | WP_000677351.1 | PTS ascorbate transporter subunit IIC | - |
| QOR49_RS01275 | - | 217356..218213 (+) | 858 | WP_283572702.1 | transketolase | - |
| QOR49_RS01280 | - | 218210..219139 (+) | 930 | WP_001203821.1 | transketolase C-terminal domain-containing protein | - |
| QOR49_RS01285 | - | 219248..220507 (+) | 1260 | WP_001203071.1 | ferric reductase-like transmembrane domain-containing protein | - |
| QOR49_RS01290 | rpsO | 220595..220864 (+) | 270 | WP_001018249.1 | 30S ribosomal protein S15 | - |
| QOR49_RS01295 | pnp | 221245..223374 (+) | 2130 | WP_000043850.1 | polyribonucleotide nucleotidyltransferase | - |
| QOR49_RS01300 | - | 223376..224128 (+) | 753 | WP_000204782.1 | SseB family protein | - |
| QOR49_RS01305 | cysE | 224137..224721 (+) | 585 | WP_000539954.1 | serine O-acetyltransferase | - |
| QOR49_RS01310 | - | 224731..224913 (+) | 183 | WP_000656476.1 | lipoprotein | - |
| QOR49_RS01315 | cysS | 224910..226253 (+) | 1344 | WP_000591125.1 | cysteine--tRNA ligase | - |
| QOR49_RS01320 | - | 226246..226632 (+) | 387 | WP_000568029.1 | Mini-ribonuclease 3 | - |
| QOR49_RS01325 | rlmB | 226735..227490 (+) | 756 | WP_000178026.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| QOR49_RS01330 | - | 227487..228005 (+) | 519 | WP_000716636.1 | NYN domain-containing protein | - |
| QOR49_RS01335 | - | 228098..228958 (+) | 861 | WP_000143135.1 | DegV family protein | - |
| QOR49_RS01340 | - | 229495..229614 (+) | 120 | Protein_208 | helix-turn-helix domain-containing protein | - |
| QOR49_RS01345 | rplM | 229839..230285 (+) | 447 | WP_001865567.1 | 50S ribosomal protein L13 | - |
| QOR49_RS01350 | rpsI | 230306..230698 (+) | 393 | WP_000035940.1 | 30S ribosomal protein S9 | - |
| QOR49_RS01355 | - | 230826..231980 (-) | 1155 | WP_000022165.1 | site-specific integrase | - |
| QOR49_RS01360 | - | 232044..232634 (-) | 591 | WP_000181098.1 | helix-turn-helix transcriptional regulator | - |
| QOR49_RS01365 | - | 232789..233094 (+) | 306 | WP_000331954.1 | hypothetical protein | - |
| QOR49_RS01370 | - | 233230..233508 (+) | 279 | WP_000134670.1 | hypothetical protein | - |
| QOR49_RS01375 | - | 233519..233749 (+) | 231 | WP_000360142.1 | hypothetical protein | - |
| QOR49_RS01380 | - | 233762..234088 (+) | 327 | WP_000384270.1 | replication initiator protein A | - |
| QOR49_RS01385 | - | 234092..234721 (+) | 630 | WP_283572703.1 | hypothetical protein | - |
| QOR49_RS01390 | - | 235034..235909 (+) | 876 | WP_000770113.1 | hypothetical protein | - |
| QOR49_RS01395 | - | 235945..236379 (+) | 435 | WP_001220479.1 | hypothetical protein | - |
| QOR49_RS01400 | mobV | 236695..237951 (+) | 1257 | WP_000122832.1 | MobV family relaxase | - |
| QOR49_RS01405 | - | 238119..238589 (+) | 471 | WP_000130119.1 | hypothetical protein | - |
| QOR49_RS01410 | - | 238894..239229 (-) | 336 | WP_000384858.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| QOR49_RS01415 | - | 239219..239506 (-) | 288 | WP_000255538.1 | hypothetical protein | - |
| QOR49_RS01420 | - | 239909..241129 (-) | 1221 | WP_000156558.1 | site-specific integrase | - |
Sequence
Protein
Download Length: 324 a.a. Molecular weight: 37046.02 Da Isoelectric Point: 4.5224
>NTDB_id=1159018 QOR49_RS01130 WP_001008574.1 190461..191435(+) (comYH) [Streptococcus agalactiae isolate MRI Z2-318]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDMVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPVGYYPNDGIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIK
Nucleotide
Download Length: 975 bp
>NTDB_id=1159018 QOR49_RS01130 WP_001008574.1 190461..191435(+) (comYH) [Streptococcus agalactiae isolate MRI Z2-318]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATGGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCTGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAGTTGG
CTATTATCCTAATGATGGTATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
67.302 |
97.222 |
0.654 |
| comYH | Streptococcus mutans UA140 |
67.302 |
97.222 |
0.654 |