Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   QOR45_RS00425 Genome accession   NZ_OX460935
Coordinates   65397..66299 (+) Length   300 a.a.
NCBI ID   WP_000912098.1    Uniprot ID   A0AAD2WWZ7
Organism   Streptococcus agalactiae isolate MRI Z2-286     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 60397..71299
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QOR45_RS00400 - 60946..62118 (+) 1173 WP_001248533.1 hypothetical protein -
  QOR45_RS00405 - 62398..62769 (+) 372 WP_001872566.1 hypothetical protein -
  QOR45_RS00410 - 62736..63140 (+) 405 WP_228305700.1 DUF6261 family protein -
  QOR45_RS00415 - 63140..63949 (+) 810 WP_000982340.1 hypothetical protein -
  QOR45_RS00420 purB 63946..65244 (+) 1299 WP_000572889.1 adenylosuccinate lyase -
  QOR45_RS00425 comR 65397..66299 (+) 903 WP_000912098.1 helix-turn-helix domain-containing protein Regulator
  QOR45_RS00430 ruvB 66588..67586 (+) 999 WP_000196633.1 Holliday junction branch migration DNA helicase RuvB -
  QOR45_RS00435 - 67738..68175 (+) 438 WP_000754818.1 low molecular weight protein-tyrosine-phosphatase -
  QOR45_RS00440 - 68182..68562 (+) 381 WP_000787702.1 membrane protein -
  QOR45_RS00445 - 68559..70337 (+) 1779 WP_283572021.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 300 a.a.        Molecular weight: 35606.08 Da        Isoelectric Point: 6.5030

>NTDB_id=1158957 QOR45_RS00425 WP_000912098.1 65397..66299(+) (comR) [Streptococcus agalactiae isolate MRI Z2-286]
MLKHFGSKVRNLRVTRNITREDFCGDETELSVRQLARIESGQSIPNLTKAHYIAKQLNVKLDILTGGESLELPKRYKELK
YKLLRTPTYGDANRLAVREAYFDEIYEVFYEELPEDERLIIDCMQSKLDVHFSVNDNFGITILHDYFDQIKKKKEYTTND
FVMIDLYLLCFSINYGMKSLYSLENYHFIMSKLLEQDNLLPEDNFQLNNVLLNHVELAFQFKQKKYVQQIIHRSNAIMTE
IHDFQKRPILSLIEWKYLLIIEKDRTKAETCFKQSILFAELIGDLYLKGKLIEEWNKDLT

Nucleotide


Download         Length: 903 bp        

>NTDB_id=1158957 QOR45_RS00425 WP_000912098.1 65397..66299(+) (comR) [Streptococcus agalactiae isolate MRI Z2-286]
ATGTTAAAACATTTTGGTAGTAAAGTAAGAAATTTGAGAGTAACTAGAAATATTACTCGCGAAGATTTTTGTGGTGATGA
AACTGAGTTATCTGTAAGACAATTAGCTAGGATTGAAAGTGGACAGTCAATTCCAAACTTGACTAAAGCTCACTACATAG
CTAAACAATTGAATGTAAAATTGGATATTTTAACAGGAGGAGAGAGCTTAGAATTACCTAAACGGTATAAAGAGTTGAAG
TACAAATTGTTGCGTACCCCGACTTACGGAGATGCTAATAGACTTGCAGTTAGAGAAGCATATTTTGATGAAATCTATGA
AGTATTTTATGAGGAGCTCCCAGAAGATGAAAGACTAATTATTGATTGTATGCAATCAAAATTAGATGTTCATTTTTCTG
TTAATGATAATTTTGGAATCACTATTTTACATGACTACTTTGATCAAATTAAGAAAAAAAAGGAATATACCACAAATGAT
TTTGTTATGATAGATTTATATTTACTTTGCTTTTCTATTAACTATGGAATGAAGAGCTTGTATTCTTTAGAGAACTATCA
TTTTATTATGTCAAAATTGTTAGAGCAAGATAATTTACTTCCTGAGGATAATTTTCAATTGAACAACGTTTTATTAAATC
ATGTCGAATTAGCTTTTCAATTTAAGCAGAAAAAATATGTACAGCAAATTATTCATAGAAGTAATGCTATTATGACAGAA
ATCCATGATTTTCAAAAAAGACCAATACTAAGCTTAATAGAGTGGAAATATTTATTAATTATTGAAAAAGATAGAACAAA
AGCAGAAACATGTTTTAAACAATCAATTCTATTTGCAGAGTTAATAGGTGATCTATATTTAAAAGGAAAATTAATAGAGG
AGTGGAATAAAGATTTAACATGA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-295)

Helix-turn-helix (HTH_3)

(10-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

59.375

96

0.57
  comR Streptococcus mutans UA159

52.174

99.667

0.52
  comR Streptococcus pyogenes MGAS8232

50.166

100

0.503
  comR Streptococcus pyogenes MGAS315

47.667

100

0.477
  comR Streptococcus suis P1/7

40.067

99

0.397
  comR Streptococcus suis 05ZYH33

40.067

99

0.397
  comR Streptococcus suis D9

36.184

100

0.367

Multiple sequence alignment