Detailed information NTG1154325

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: AD178_RS06215
• Genome accession: NZ_OX244288
• Coordinates: 1229470..1230318 (-)
• Length: 282 a.a.
• NCBI ID: WP_000705325.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PT8105 isolate 2RLC4
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1224470..1235318

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AD178_RS06200 (SAMEA1463109_01252)	-	1224754..1225113 (-)	360	WP_001220357.1	YbaN family protein	-
AD178_RS06205 (SAMEA1463109_01253)	topA	1225334..1227421 (-)	2088	WP_000179635.1	type I DNA topoisomerase	-
AD178_RS06210 (SAMEA1463109_01254)	-	1227588..1228631 (-)	1044	WP_001812710.1	TIGR00341 family protein	-
AD178_RS06215 (SAMEA1463109_01255)	dprA/cilB/dalA	1229470..1230318 (-)	849	WP_000705325.1	DNA-processing protein DprA	Machinery gene
AD178_RS06220 (SAMEA1463109_01256)	-	1230414..1231103 (-)	690	WP_000643970.1	sugar phosphate nucleotidyltransferase	-
AD178_RS06225 (SAMEA1463109_01257)	-	1231115..1231993 (-)	879	WP_000837609.1	DMT family transporter	-
AD178_RS06230 (SAMEA1463109_01258)	licA	1231983..1232852 (-)	870	WP_000411207.1	choline kinase LicA	-
AD178_RS06235 (SAMEA1463109_01259)	-	1232869..1233891 (-)	1023	WP_000609888.1	ribitol-5-phosphate dehydrogenase	-
AD178_RS06240 (SAMEA1463109_01260)	-	1233896..1234603 (-)	708	WP_000638482.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31164.81 Da
• Isoelectric Point: 5.2061

>NTDB_id=1154325 AD178_RS06215 WP_000705325.1 1229470..1230318(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
MKITNYEIYKLKKSSLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKTVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPDSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=1154325 AD178_RS06215 WP_000705325.1 1229470..1230318(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAAGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGACAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGATAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	98.936	100	0.989
dprA/cilB/dalA	Streptococcus pneumoniae D39	98.936	100	0.989
dprA/cilB/dalA	Streptococcus pneumoniae R6	98.936	100	0.989
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	98.936	100	0.989
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	97.518	100	0.975
dprA/cilB/dalA	Streptococcus mitis SK321	96.809	100	0.968
dprA	Streptococcus mutans UA159	62.5	99.291	0.621
dprA	Lactococcus lactis subsp. cremoris KW2	54.643	99.291	0.543
dprA	Staphylococcus aureus N315	37.102	100	0.372