Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   AD178_RS00520 Genome accession   NZ_OX244288
Coordinates   83481..84830 (+) Length   449 a.a.
NCBI ID   WP_000801591.1    Uniprot ID   A0A4V0IRK4
Organism   Streptococcus pneumoniae strain PT8105 isolate 2RLC4     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 78481..89830
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AD178_RS00490 (SAMEA1463109_00102) plsX 78599..79591 (+) 993 WP_000717458.1 phosphate acyltransferase PlsX -
  AD178_RS00495 (SAMEA1463109_00103) - 79597..79830 (+) 234 WP_000136449.1 acyl carrier protein -
  AD178_RS00500 - 79876..80167 (+) 292 Protein_92 IS5/IS1182 family transposase -
  AD178_RS00505 (SAMEA1463109_00104) blpU 80370..80600 (+) 231 WP_001093075.1 bacteriocin-like peptide BlpU -
  AD178_RS00510 (SAMEA1463109_00105) - 80603..80728 (+) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  AD178_RS00515 (SAMEA1463109_00106) comA 81315..83468 (+) 2154 WP_000668294.1 peptide cleavage/export ABC transporter ComA Regulator
  AD178_RS00520 (SAMEA1463109_00107) comB 83481..84830 (+) 1350 WP_000801591.1 competence pheromone export protein ComB Regulator
  AD178_RS00525 (SAMEA1463109_00108) purC 85000..85707 (+) 708 WP_000043304.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  AD178_RS11095 - 85718..85852 (+) 135 WP_000429436.1 hypothetical protein -
  AD178_RS00530 (SAMEA1463109_00109) - 85909..89634 (+) 3726 WP_000361217.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49694.60 Da        Isoelectric Point: 5.5684

>NTDB_id=1154302 AD178_RS00520 WP_000801591.1 83481..84830(+) (comB) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
MKPEFLESAEFYNRRYHNFSSRVIVPMSLLLVFLLGFATFAEKEISLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGEENPQIKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1154302 AD178_RS00520 WP_000801591.1 83481..84830(+) (comB) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTGTACCCAT
GTCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACATTTGCGGAGAAGGAGATAAGTTTATCAACTAGAGCTACTGTCG
AGCCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAAGAAAATCCCCAAATTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACATTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0IRK4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

98.441

100

0.984
  comB Streptococcus pneumoniae D39

98.218

100

0.982
  comB Streptococcus pneumoniae R6

98.218

100

0.982
  comB Streptococcus pneumoniae Rx1

98.218

100

0.982
  comB Streptococcus mitis SK321

95.546

100

0.955
  comB Streptococcus mitis NCTC 12261

94.655

100

0.947
  comB Streptococcus gordonii str. Challis substr. CH1

55.778

100

0.559

Multiple sequence alignment