Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   NBW44_RS04490 Genome accession   NZ_OW724079
Coordinates   889395..890066 (-) Length   223 a.a.
NCBI ID   WP_250307378.1    Uniprot ID   -
Organism   Streptococcus sp. Marseille-Q3533     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 884395..895066
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NBW44_RS04470 rpiA 885611..886294 (-) 684 WP_250307374.1 ribose-5-phosphate isomerase RpiA -
  NBW44_RS04475 - 886399..887328 (-) 930 WP_250307375.1 peptidase U32 family protein -
  NBW44_RS04480 - 887764..888039 (+) 276 WP_250307376.1 DUF3270 family protein -
  NBW44_RS04485 ciaH 888068..889402 (-) 1335 WP_250307377.1 HAMP domain-containing sensor histidine kinase Regulator
  NBW44_RS04490 ciaR 889395..890066 (-) 672 WP_250307378.1 response regulator transcription factor Regulator
  NBW44_RS04495 - 890181..892727 (-) 2547 WP_250307379.1 M1 family metallopeptidase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25320.11 Da        Isoelectric Point: 4.3880

>NTDB_id=1152601 NBW44_RS04490 WP_250307378.1 889395..890066(-) (ciaR) [Streptococcus sp. Marseille-Q3533]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGISTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLTYGDLTVNLSTNEVKVQDASVELLGKEFELLIY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGSAFAENLQTLRSVGYILKHV

Nucleotide


Download         Length: 672 bp        

>NTDB_id=1152601 NBW44_RS04490 WP_250307378.1 889395..890066(-) (ciaR) [Streptococcus sp. Marseille-Q3533]
ATGATTAAAATTCTATTAGTGGAAGATGACCTAGGTCTGTCAAATTCAGTTTTTGATTTTTTGGATGATTTTGCGGATGT
CATGCAGGTTTTTGATGGCGAAGAAGGTCTCTACGAGGCTGAAAGTGGCGTTTATGACTTGATTCTCCTTGATTTAATGT
TACCTGAAAAAAATGGTTTCCAAGTCTTAAAAGAATTACGTGAAAAAGGCATTTCGACCCCTGTTCTCATCATGACAGCC
AAGGAAAGTCTCGATGACAAAGGACATGGCTTTGAGCTTGGGGCTGATGATTATCTAACCAAACCATTCTACCTAGAAGA
ACTCAAGATGCGTATTCAGGCCCTTCTCAAACGTTCTGGGAAATTTAACGAAAATACCTTAACGTACGGTGATTTGACTG
TCAATCTATCTACTAATGAAGTTAAGGTTCAAGATGCCTCTGTTGAGCTGCTTGGTAAAGAATTTGAACTATTGATCTAT
TTCCTCCAAAACCAAAATGTCATCTTACCAAAAACCCAAATCTTTGATCGTTTATGGGGATTTGACAGTGACACAACCAT
CTCCGTTGTAGAAGTTTATGTATCAAAAGTTCGTAAGAAATTGAAAGGTTCAGCCTTTGCTGAAAACCTTCAAACTCTAC
GTAGTGTTGGGTATATTTTAAAACATGTTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae TIGR4

93.722

100

0.937
  ciaR Streptococcus pneumoniae D39

93.722

100

0.937
  ciaR Streptococcus pneumoniae R6

93.722

100

0.937
  ciaR Streptococcus pneumoniae Rx1

93.722

100

0.937
  ciaR Streptococcus mutans UA159

87.783

99.103

0.87
  vicR Streptococcus mutans UA159

36.052

100

0.377
  covR Lactococcus lactis subsp. lactis strain DGCC12653

36.444

100

0.368

Multiple sequence alignment