Detailed information NTG1152600

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: NBW44_RS04485
• Genome accession: NZ_OW724079
• Coordinates: 888068..889402 (-)
• Length: 444 a.a.
• NCBI ID: WP_250307377.1
• Uniprot ID: -
• Organism: Streptococcus sp. Marseille-Q3533
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 883068..894402

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NBW44_RS04460	-	883814..884374 (-)	561	WP_250307372.1	DUF1697 domain-containing protein	-
NBW44_RS04465	-	884376..885587 (-)	1212	WP_250307373.1	phosphopentomutase	-
NBW44_RS04470	rpiA	885611..886294 (-)	684	WP_250307374.1	ribose-5-phosphate isomerase RpiA	-
NBW44_RS04475	-	886399..887328 (-)	930	WP_250307375.1	peptidase U32 family protein	-
NBW44_RS04480	-	887764..888039 (+)	276	WP_250307376.1	DUF3270 family protein	-
NBW44_RS04485	ciaH	888068..889402 (-)	1335	WP_250307377.1	HAMP domain-containing sensor histidine kinase	Regulator
NBW44_RS04490	ciaR	889395..890066 (-)	672	WP_250307378.1	response regulator transcription factor	Regulator
NBW44_RS04495	-	890181..892727 (-)	2547	WP_250307379.1	M1 family metallopeptidase	-

Sequence

Protein

• Length: 444 a.a.
• Molecular weight: 50855.47 Da
• Isoelectric Point: 9.2163

>NTDB_id=1152600 NBW44_RS04485 WP_250307377.1 888068..889402(-) (ciaH) [Streptococcus sp. Marseille-Q3533]
MFNKIRKNWYAEDFSYFVRNFGVFTLIFSAMTLIILQVMHSSLYTSVDEKLQSLSSKPQDVIQLALDRTTEDIKDLNNES
VAKSGDKKPTVSSNTEVILFDENLNQLITGNRFLGLDKITFNKKDLNHIRQLHIQNSFGQDEIYRVLLTEINFESVSTNI
KYAAVLINTSQLEQISQNHEQLIVVVMASFWILSLLASLYLARVSVKPLLESMQKQQSFVENASHELRTPLAVLQNRLET
LFRKPEATIMESSESIASSLEEVRNMRLLTTNLLNLARRDDGIKPDLGEVQPEFFNTIFTNYEMIATENHKVFRFENRIK
RTIITDKLLLKQLMTILFDNAVKYTEEDGEINFVITATDRNLYLTVSDDGIGIPQADKKKIFDRFYRVDKARTRQKGGFG
LGLSLAKQIVDALKGSISVKDNKPHGTIFEIKIAIQTPPKRKNK

Nucleotide

• Length: 1335 bp

>NTDB_id=1152600 NBW44_RS04485 WP_250307377.1 888068..889402(-) (ciaH) [Streptococcus sp. Marseille-Q3533]
ATGTTTAATAAAATAAGAAAGAATTGGTACGCAGAAGATTTCAGCTACTTTGTCCGTAACTTTGGTGTCTTTACGCTTAT
CTTCTCTGCTATGACCTTGATTATCTTGCAAGTTATGCACTCGAGTCTTTATACTTCAGTAGATGAAAAGTTGCAGAGCT
TAAGTAGCAAGCCTCAAGATGTGATTCAGTTGGCTTTAGATAGAACGACAGAGGATATAAAAGATCTGAACAATGAATCT
GTTGCAAAATCGGGGGATAAGAAACCTACTGTTAGTTCAAATACAGAAGTAATCCTGTTCGATGAAAATCTGAATCAATT
GATAACGGGGAATCGCTTTTTAGGTTTAGACAAAATTACCTTTAATAAAAAGGATTTAAATCATATCCGACAGCTTCATA
TTCAGAATAGTTTTGGACAGGATGAGATTTATCGAGTTCTCCTAACAGAAATAAATTTTGAGAGCGTTTCGACCAATATT
AAATACGCTGCCGTATTGATTAATACCAGTCAATTAGAGCAAATCAGTCAGAATCATGAACAGCTGATCGTTGTTGTAAT
GGCTAGTTTTTGGATTTTATCACTTCTAGCTAGTCTGTATCTTGCTAGAGTTAGTGTCAAACCTTTACTTGAAAGCATGC
AGAAACAACAAAGCTTTGTTGAGAATGCCAGTCATGAGCTTCGTACACCTTTAGCAGTTTTGCAAAATCGTTTGGAAACA
CTTTTTCGCAAACCTGAAGCTACCATTATGGAGTCTAGTGAGAGTATAGCTTCAAGTCTAGAAGAAGTGCGTAATATGCG
CCTTTTAACAACTAATCTTCTCAATCTAGCCCGTCGTGATGATGGGATTAAGCCGGATTTAGGTGAGGTTCAACCAGAAT
TTTTCAACACAATTTTTACAAACTATGAAATGATTGCAACTGAGAATCATAAAGTCTTTCGTTTTGAAAATAGAATCAAG
CGTACCATTATTACAGACAAGCTTCTCCTTAAGCAATTAATGACAATCCTCTTTGATAATGCTGTAAAGTATACAGAAGA
AGACGGAGAGATTAATTTTGTGATTACTGCAACAGATCGTAACTTGTACTTGACTGTATCGGATGACGGTATTGGTATAC
CACAAGCAGATAAAAAGAAAATATTTGATCGCTTTTACAGGGTTGATAAGGCCAGAACTAGACAAAAGGGTGGATTTGGT
CTTGGCTTATCCCTGGCTAAACAAATTGTCGATGCCCTCAAAGGATCCATCAGTGTTAAAGATAATAAACCTCATGGAAC
TATTTTTGAGATAAAAATCGCTATCCAAACACCGCCCAAACGTAAAAATAAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-433)

• His Kinase A (phospho-acceptor) domain (HisKA) (216-282)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus pneumoniae Rx1	80.813	99.775	0.806
ciaH	Streptococcus pneumoniae D39	80.813	99.775	0.806
ciaH	Streptococcus pneumoniae R6	80.813	99.775	0.806
ciaH	Streptococcus pneumoniae TIGR4	80.813	99.775	0.806
ciaH	Streptococcus mutans UA159	54.965	97.523	0.536