Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   MD993_RS05640 Genome accession   NZ_OV648025
Coordinates   1200810..1201682 (+) Length   290 a.a.
NCBI ID   WP_031786943.1    Uniprot ID   -
Organism   Staphylococcus argenteus isolate 20S00001-1_long     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1164214..1246584 1200810..1201682 within 0


Gene organization within MGE regions


Location: 1164214..1246584
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MD993_RS05475 - 1164369..1164572 (-) 204 WP_001198027.1 TM2 domain-containing protein -
  MD993_RS05480 - 1164873..1165361 (+) 489 WP_031787794.1 peptide deformylase -
  MD993_RS05485 fmt 1165354..1166289 (+) 936 WP_000161302.1 methionyl-tRNA formyltransferase -
  MD993_RS05490 rsmB 1166286..1167593 (+) 1308 WP_031787795.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  MD993_RS05495 rlmN 1167596..1168690 (+) 1095 WP_000626892.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  MD993_RS05500 - 1168697..1169440 (+) 744 WP_000888496.1 protein-serine/threonine phosphatase Stp1 -
  MD993_RS05505 pknB 1169437..1171431 (+) 1995 WP_031787796.1 serine/threonine protein kinase Stk1 -
  MD993_RS05510 rsgA 1171698..1172573 (+) 876 WP_000847920.1 ribosome small subunit-dependent GTPase A -
  MD993_RS05515 rpe 1172574..1173218 (+) 645 WP_237792744.1 ribulose-phosphate 3-epimerase -
  MD993_RS05520 - 1173225..1173869 (+) 645 WP_031787798.1 thiamine diphosphokinase -
  MD993_RS05525 rpmB 1174119..1174307 (-) 189 WP_000517908.1 50S ribosomal protein L28 -
  MD993_RS05530 - 1174751..1175125 (+) 375 WP_031787799.1 Asp23/Gls24 family envelope stress response protein -
  MD993_RS05535 fakA 1175140..1176786 (+) 1647 WP_031787800.1 fatty acid kinase catalytic subunit FakA -
  MD993_RS05540 recG 1176960..1179020 (+) 2061 WP_031787801.1 ATP-dependent DNA helicase RecG -
  MD993_RS05545 fapR 1179425..1179997 (+) 573 WP_072292002.1 transcription factor FapR -
  MD993_RS05550 plsX 1180002..1180988 (+) 987 WP_000239751.1 phosphate acyltransferase PlsX -
  MD993_RS05555 fabD 1180981..1181907 (+) 927 WP_031787802.1 ACP S-malonyltransferase -
  MD993_RS05560 fabG 1181900..1182634 (+) 735 WP_000167268.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  MD993_RS05565 - 1183104..1183337 (+) 234 WP_000426914.1 acyl carrier protein -
  MD993_RS05570 rnc 1183453..1184184 (+) 732 WP_000043235.1 ribonuclease III -
  MD993_RS05575 smc 1184316..1187885 (+) 3570 WP_031788253.1 chromosome segregation protein SMC -
  MD993_RS05580 ftsY 1187882..1189132 (+) 1251 WP_031788254.1 signal recognition particle-docking protein FtsY -
  MD993_RS05585 - 1189119..1189451 (+) 333 WP_000531321.1 putative DNA-binding protein -
  MD993_RS05590 ffh 1189476..1190843 (+) 1368 WP_000863483.1 signal recognition particle protein -
  MD993_RS05595 rpsP 1191172..1191447 (+) 276 WP_000268754.1 30S ribosomal protein S16 -
  MD993_RS05600 rimM 1191634..1192137 (+) 504 WP_001261978.1 ribosome maturation factor RimM -
  MD993_RS05605 trmD 1192137..1192874 (+) 738 WP_031786939.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  MD993_RS05610 rplS 1192977..1193327 (+) 351 WP_000181404.1 50S ribosomal protein L19 -
  MD993_RS05615 - 1193569..1196175 (-) 2607 WP_031786940.1 YfhO family protein -
  MD993_RS05620 ylqF 1196575..1197459 (+) 885 WP_031786941.1 ribosome biogenesis GTPase YlqF -
  MD993_RS05625 - 1197443..1198210 (+) 768 WP_031786942.1 ribonuclease HII -
  MD993_RS05630 sucC 1198319..1199485 (+) 1167 WP_001020805.1 ADP-forming succinate--CoA ligase subunit beta -
  MD993_RS05635 sucD 1199507..1200415 (+) 909 WP_000110253.1 succinate--CoA ligase subunit alpha -
  MD993_RS05640 dprA 1200810..1201682 (+) 873 WP_031786943.1 DNA-processing protein DprA Machinery gene
  MD993_RS05645 topA 1201856..1203931 (+) 2076 WP_072324151.1 type I DNA topoisomerase -
  MD993_RS05650 trmFO 1204087..1205394 (+) 1308 WP_000195261.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  MD993_RS05655 xerC 1205809..1206705 (+) 897 WP_031786945.1 tyrosine recombinase XerC -
  MD993_RS05660 hslV 1206702..1207247 (+) 546 WP_000072683.1 ATP-dependent protease subunit HslV -
  MD993_RS05665 hslU 1207312..1208715 (+) 1404 WP_000381629.1 ATP-dependent protease ATPase subunit HslU -
  MD993_RS05670 codY 1208740..1209513 (+) 774 WP_000055333.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  MD993_RS05675 rpsB 1209790..1210557 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  MD993_RS05680 - 1210609..1210704 (+) 96 WP_225995268.1 hypothetical protein -
  MD993_RS05685 tsf 1210739..1211620 (+) 882 WP_031786946.1 translation elongation factor Ts -
  MD993_RS05690 pyrH 1211757..1212479 (+) 723 WP_000057330.1 UMP kinase -
  MD993_RS05695 frr 1212498..1213052 (+) 555 WP_001280034.1 ribosome recycling factor -
  MD993_RS05700 - 1213413..1214183 (+) 771 WP_000473698.1 isoprenyl transferase -
  MD993_RS05705 - 1214190..1214972 (+) 783 WP_000868415.1 phosphatidate cytidylyltransferase -
  MD993_RS05710 rseP 1215183..1216469 (+) 1287 WP_031786947.1 RIP metalloprotease RseP -
  MD993_RS05715 - 1216489..1218192 (+) 1704 WP_031786948.1 proline--tRNA ligase -
  MD993_RS05720 - 1218466..1222776 (+) 4311 WP_078097697.1 PolC-type DNA polymerase III -
  MD993_RS05725 rimP 1223052..1223519 (+) 468 WP_031786950.1 ribosome maturation factor RimP -
  MD993_RS05730 nusA 1223540..1224715 (+) 1176 WP_000097470.1 transcription termination factor NusA -
  MD993_RS05735 rnpM 1224736..1225020 (+) 285 WP_031786951.1 RNase P modulator RnpM -
  MD993_RS05740 - 1225017..1225334 (+) 318 WP_000021269.1 YlxQ family RNA-binding protein -
  MD993_RS05745 infB 1225339..1227465 (+) 2127 WP_000043647.1 translation initiation factor IF-2 -
  MD993_RS05750 rbfA 1227794..1228144 (+) 351 WP_000097321.1 30S ribosome-binding factor RbfA -
  MD993_RS05755 truB 1228316..1229233 (+) 918 WP_000282309.1 tRNA pseudouridine(55) synthase TruB -
  MD993_RS05760 ribF 1229248..1230219 (+) 972 WP_031786952.1 riboflavin biosynthesis protein RibF -
  MD993_RS05765 rpsO 1230334..1230603 (+) 270 WP_001018327.1 30S ribosomal protein S15 -
  MD993_RS05770 pnp 1230970..1233066 (+) 2097 WP_000076680.1 polyribonucleotide nucleotidyltransferase -
  MD993_RS05775 rnjB 1233309..1234982 (+) 1674 WP_000052592.1 ribonuclease J2 -
  MD993_RS05780 - 1235254..1237626 (+) 2373 WP_031786953.1 DNA translocase FtsK -
  MD993_RS05785 - 1237630..1238343 (+) 714 WP_001293301.1 GntR family transcriptional regulator -
  MD993_RS05790 yfmF 1238374..1239639 (+) 1266 WP_031786954.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  MD993_RS05795 yfmH 1239639..1240925 (+) 1287 WP_031786955.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  MD993_RS05800 ymfI 1240925..1241629 (+) 705 WP_000646238.1 elongation factor P 5-aminopentanone reductase -
  MD993_RS05805 - 1241737..1242564 (+) 828 WP_031786956.1 DUF3388 domain-containing protein -
  MD993_RS05810 - 1242589..1242981 (+) 393 WP_000859442.1 RodZ family helix-turn-helix domain-containing protein -
  MD993_RS05815 pgsA 1243013..1243591 (+) 579 WP_031786957.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MD993_RS05820 - 1243833..1244984 (+) 1152 WP_031786958.1 CinA family nicotinamide mononucleotide deamidase-related protein -
  MD993_RS05825 recA 1245149..1246192 (+) 1044 WP_000368169.1 recombinase RecA Machinery gene
  MD993_RS12955 - 1246374..1246519 (-) 146 Protein_1142 ISL3 family transposase -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33128.01 Da        Isoelectric Point: 9.3910

>NTDB_id=1151890 MD993_RS05640 WP_031786943.1 1200810..1201682(+) (dprA) [Staphylococcus argenteus isolate 20S00001-1_long]
MLNQILLKLIWSHFTTSQIHQLFNKFPNFLEVDELEQNYLLRKFVLNNSNENLSIKNEVYSRISFDEIMSNIQQSKLNFI
TCFDKGYPSYLKEIYDYPFVLFYKGSINILSSPKALAVVGSRVSSNYTTKALNHLFYSFQQSNLTIVSGLAQGADAMAHQ
TALKYNLPTIAVLAFGHQTHYPKSTRALRNKIEEKGLVISEYPPHTPIARYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDILEDYFI

Nucleotide


Download         Length: 873 bp        

>NTDB_id=1151890 MD993_RS05640 WP_031786943.1 1200810..1201682(+) (dprA) [Staphylococcus argenteus isolate 20S00001-1_long]
ATGTTAAATCAAATTCTACTTAAATTAATTTGGAGTCATTTTACAACTTCGCAAATTCACCAGCTATTTAATAAATTTCC
AAACTTTTTAGAAGTAGATGAACTTGAACAAAATTATCTACTACGCAAATTTGTTTTAAATAATTCAAATGAGAATCTTT
CGATTAAAAATGAGGTTTATAGTCGAATTTCTTTTGATGAAATAATGTCAAATATCCAACAAAGCAAATTGAACTTTATA
ACTTGTTTTGATAAAGGGTATCCTAGTTACTTAAAAGAAATTTACGACTATCCATTTGTTTTATTTTATAAAGGGAGTAT
TAATATCCTCAGTTCTCCTAAAGCATTAGCTGTAGTTGGTTCGAGAGTTTCAAGCAATTATACAACAAAAGCATTGAACC
ATCTTTTCTATTCGTTCCAACAATCAAATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ACAGCATTAAAATACAATCTCCCTACAATAGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACACGAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTGATATCCGAATATCCACCGCATACACCAATTGCTAGATATAGATTTC
CAGAACGAAATAGAATTATCAGTGGGTTGTCAAAAGGGGTTCTAATAACAGAAGCTAAAGAACAAAGTGGTAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAACAGAAATGTTTATGTTTTACCAGGATCAATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGAGCTAAGGTAGTTTTAAACGCTAATGATATATTAGAAGATTACTTTATTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

67.123

100

0.676
  dprA Staphylococcus aureus N315

67.123

100

0.676
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

37.722

96.897

0.366
  dprA/cilB/dalA Streptococcus pneumoniae D39

37.722

96.897

0.366
  dprA/cilB/dalA Streptococcus pneumoniae R6

37.722

96.897

0.366
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

37.722

96.897

0.366
  dprA/cilB/dalA Streptococcus mitis SK321

37.722

96.897

0.366
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

37.367

96.897

0.362

Multiple sequence alignment